Access the full text.
Sign up today, get DeepDyve free for 14 days.
H. Gelbard-Sagiv, R. Mukamel, M. Harel, R. Malach, I. Fried (2008)
Internally Generated Reactivation of Single Neurons in Human Hippocampus During Free RecallScience, 322
B. Givens (1996)
Stimulus‐evoked resetting of the dentate theta rhythm: relation to working memoryNeuroReport, 8
S. Mizumori, David Smith, C. Puryear (2007)
Hippocampal and neocortical interactions during context discrimination: Electrophysiological evidence from the ratHippocampus, 17
P. Kennedy, M. Shapiro (2009)
Motivational states activate distinct hippocampal representations to guide goal-directed behaviorsProceedings of the National Academy of Sciences, 106
Pastalkova Pastalkova, Itskov Itskov, Amarasingham Amarasingham, Buzsaki Buzsaki (2008)
Internally generated cell assembly sequences in the rat hippocampusScience, 321
M. Jarvis, P. Mitra (2000)
Sampling Properties of the Spectrum and Coherency of Sequences of Action PotentialsNeural Computation, 13
David Smith, S. Mizumori (2006)
Hippocampal place cells, context, and episodic memoryHippocampus, 16
E. Wood, Paul Dudchenko, R. Robitsek, H. Eichenbaum (2000)
Hippocampal Neurons Encode Information about Different Types of Memory Episodes Occurring in the Same LocationNeuron, 27
M. Eckardt (1980)
The Hippocampus as a Cognitive MapJournal of Nervous and Mental Disease, 168
(2003)
Hippocampal neurons develop context-specific firing patterns during spatial learning
O. Yeshenko, A. Guazzelli, S. Mizumori (2004)
Context-dependent reorganization of spatial and movement representations by simultaneously recorded hippocampal and striatal neurons during performance of allocentric and egocentric tasks.Behavioral neuroscience, 118 4
Mathew Wilson, B. McNaughton (1994)
Reactivation of hippocampal ensemble memories during sleep.Science, 265 5172
Muneyoshi Takahashi, J. Lauwereyns, Y. Sakurai, M. Tsukada (2009)
Behavioral state-dependent episodic representations in rat CA1 neuronal activity during spatial alternationCognitive Neurodynamics, 3
G. Dragoi, G. Buzsáki (2006)
Temporal Encoding of Place Sequences by Hippocampal Cell AssembliesNeuron, 50
B. Bland, D. Derie-Gillespie, P. Mestek, Jd Jackson, R. Crooks, A. Cormican (2007)
To move or not: Previous experience in a runway avoidance task determines the appearance of hippocampal Type 2 sensory processing thetaBehavioural Brain Research, 179
David Smith (2008)
The hippocampus , context processing and episodic memory
L. Squire, S. Zola-Morgan (1991)
The medial temporal lobe memory systemScience, 253
E. Markus, Yu Qin, B. Leonard, W. Skaggs, B. McNaughton, C. Barnes (1995)
Interactions between location and task affect the spatial and directional firing of hippocampal neurons, 15
B. Bland (1986)
The physiology and pharmacology of hippocampal formation theta rhythmsProgress in Neurobiology, 26
K. Diba, G. Buzsáki (2007)
Forward and reverse hippocampal place-cell sequences during ripplesNature Neuroscience, 10
H. Eichenbaum (2008)
Faculty Opinions recommendation of Internally generated cell assembly sequences in the rat hippocampus.
W. Levy, A. Sanyal, Xiangbao Wu, P. Rodríguez, D. Sullivan (2005)
The formation of neural codes in the hippocampus: trace conditioning as a prototypical paradigm for studying the random recoding hypothesisBiological Cybernetics, 92
David Smith, S. Mizumori (2006)
Learning-Related Development of Context-Specific Neuronal Responses to Places and Events: The Hippocampal Role in Context ProcessingThe Journal of Neuroscience, 26
J. Ferbinteanu, M. Shapiro (2003)
Prospective and Retrospective Memory Coding in the HippocampusNeuron, 40
(2000)
pocampal
J. Ainge, Matthijs Meer, R. Langston, E. Wood (2007)
Exploring the role of context‐dependent hippocampal activity in spatial alternation behaviorHippocampus, 17
David Smith (2008)
Chapter 4.4 The hippocampus, context processing and episodic memoryHandbook of Behavioral Neuroscience, 18
M. Seager, Lynn Johnson, Elizabeth Chabot, Y. Asaka, S. Berry (2002)
Oscillatory brain states and learning: Impact of hippocampal theta-contingent trainingProceedings of the National Academy of Sciences of the United States of America, 99
S. Funahashi, C. Bruce, P. Goldman-Rakic (1989)
Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex.Journal of neurophysiology, 61 2
R. Morris, P. Garrud, J. Rawlins, J. O’Keefe (1982)
Place navigation impaired in rats with hippocampal lesionsNature, 297
B. McNaughton, J. O’Keefe, C. Barnes (1983)
The stereotrode: A new technique for simultaneous isolation of several single units in the central nervous system from multiple unit recordsJournal of Neuroscience Methods, 8
W. Skaggs, B. McNaughton (1998)
Spatial Firing Properties of Hippocampal CA1 Populations in an Environment Containing Two Visually Identical RegionsThe Journal of Neuroscience, 18
D. Ji, M. Wilson (2007)
Coordinated memory replay in the visual cortex and hippocampus during sleepNature Neuroscience, 10
Several recent studies have shown that hippocampal neurons fire during the delay period in between trials and that these firing patterns differ when different behaviors are required, suggesting that the neuronal responses may be involved in maintaining the memories needed for the upcoming trial. In particular, one study found that hippocampal neurons reliably fired at particular times, referred to as “episode fields” (EFs), during the delay period of a spatial alternation task (Pastalkova et al. (2008) Science 321:1322–1327). The firing of these neurons resulted in distinct sequential firing patterns on left and right turn trials, and these firing patterns could be used to predict the upcoming behavioral response. In this study, we examined neuronal firing during the delay period of a hippocampus‐dependent plus maze task, which involved learning to approach two different reward locations (east and west), and we examined the development of these firing patterns with learning. As in the previous study, hippocampal neurons exhibited discrete periods of elevated firing during the delay (EFs) and the firing patterns were distinct on the east and west trials. Moreover, these firing patterns emerged and began to differentiate the east and west conditions during the first training session and continued to develop as the rats learned the task. The finding of similar firing patterns in different tasks suggests that the EFs are a robust phenomenon, which may occur whenever subjects must maintain distinct memory representations during a delay period. Additionally, in the previous study (Pastalkova et al. (2008) Science 321:1322–1327), the distinct firing patterns could have been due to the differing goal locations, behavioral responses (left or right turns), or trajectories. In this study, neuronal firing varied with the goal location regardless of the trajectories or responses, suggesting that the firing patterns encode the behavioral context rather than specific behaviors. ©2010 Wiley Periodicals, Inc.
Hippocampus – Wiley
Published: Nov 1, 2011
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.