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Hexammineruthenium(III) ion interactions with Z‐DNA

Hexammineruthenium(III) ion interactions with Z‐DNA The hexamer duplex d(CGCGCA)·d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 Å resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A·T base pairing is disrupted. This structural study may be relevant to metal toxicity. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Crystallographica Section F Wiley

Hexammineruthenium(III) ion interactions with Z‐DNA

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References (34)

Publisher
Wiley
Copyright
Copyright © 2007 Wiley Subscription Services, Inc., A Wiley Company
ISSN
1744-3091
eISSN
1744-3091
DOI
10.1107/S1744309107047781
pmid
18084080
Publisher site
See Article on Publisher Site

Abstract

The hexamer duplex d(CGCGCA)·d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 Å resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A·T base pairing is disrupted. This structural study may be relevant to metal toxicity.

Journal

Acta Crystallographica Section FWiley

Published: Dec 1, 2007

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