Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Genomic sequencing in oncology: Considerations for integration in routine cancer care

Genomic sequencing in oncology: Considerations for integration in routine cancer care INTRODUCTIONIn the United Kingdom (UK), efforts to incorporate genome sequencing into clinical care were significantly boosted by implementation of the 100,000 Genomes Project in 2014. The UK now transitions to the next phase of delivering genomic sequencing within the National Health Service (NHS) via the Genomic Medicine Service (GMS). A National Genomic Test Directory has been developed to specify the genomic tests that can be ordered and funded by the NHS, including testing criteria, scope and technology. Mainstreaming of genomic sequencing is a key component of the GMS which enables multispecialty clinicians, including oncologists, to directly order specific genomic tests aimed at improving access to testing for their patients.In practice, how genomic sequencing will be adopted and used within oncology remains unclear. A systematic review of factors for successful implementation of genomic medicine in routine health care identified the need for practice reform, genomics education and training, validation of clinical utility and cost‐effectiveness, and adaptations to models of care (Pearce et al., 2019). In particular, the integration of genomics into mainstream oncology will require ‘… upskilling other healthcare professionals in genomics’ to manage genomic testing capacity, interpretation of results and implementation of changes in clinical care (Bancroft et al., 2020). Healthcare http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Cancer Care Wiley

Genomic sequencing in oncology: Considerations for integration in routine cancer care

Download PDF
4 pages

Loading next page...
 
/lp/wiley/genomic-sequencing-in-oncology-considerations-for-integration-in-0fPVX4txTp

References (27)

Publisher
Wiley
Copyright
© 2022 John Wiley & Sons Ltd
ISSN
0961-5423
eISSN
1365-2354
DOI
10.1111/ecc.13584
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONIn the United Kingdom (UK), efforts to incorporate genome sequencing into clinical care were significantly boosted by implementation of the 100,000 Genomes Project in 2014. The UK now transitions to the next phase of delivering genomic sequencing within the National Health Service (NHS) via the Genomic Medicine Service (GMS). A National Genomic Test Directory has been developed to specify the genomic tests that can be ordered and funded by the NHS, including testing criteria, scope and technology. Mainstreaming of genomic sequencing is a key component of the GMS which enables multispecialty clinicians, including oncologists, to directly order specific genomic tests aimed at improving access to testing for their patients.In practice, how genomic sequencing will be adopted and used within oncology remains unclear. A systematic review of factors for successful implementation of genomic medicine in routine health care identified the need for practice reform, genomics education and training, validation of clinical utility and cost‐effectiveness, and adaptations to models of care (Pearce et al., 2019). In particular, the integration of genomics into mainstream oncology will require ‘… upskilling other healthcare professionals in genomics’ to manage genomic testing capacity, interpretation of results and implementation of changes in clinical care (Bancroft et al., 2020). Healthcare

Journal

European Journal of Cancer Care – Wiley

Published: May 1, 2022

Keywords: clinical practice; genome sequencing; genomic medicine; oncology; routine care

There are no references for this article.