Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Genetic studies on hybrid populations I. Individual estimates of ancestry and their relation to quantitative traits

Genetic studies on hybrid populations I. Individual estimates of ancestry and their relation to... Genetic studies on hybrid populations I. Individual estimates of ancestry and their relation to quantitative traits BY CHARLES J. MACLEAN Human Genetics Branch, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20014 PETER L. WORKMAN Division of Medical Genetics, M t Sinai School of Medicine, New York, New York 10029 AND 1NTRODUCTION Any two human populations may be assumed t o differ genetically, in the relative frequencies of alleles present in both populations, and, possibly, in the types of alleles represented a t a locus. For qualitative traits the differences can be demonstrated simply by a comparison of the frequencies of the alleles a t one or more loci. However, for heritable quantitative traits, especially those whose environmental component of variation is in part the result of cultural factors, there appears to be no direct method for interpopulation comparisons. The genes controlling variation in such traits cannot be identified, and the effects of differing physical and cultural environments, the complications of social heredity, and genotype-environment interactions, all make the prospect for such comparisons poor. Thus, as discussed by Thoday (1969), there appears t o be no direct answer to the question of whether there are http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

Genetic studies on hybrid populations I. Individual estimates of ancestry and their relation to quantitative traits

Loading next page...
 
/lp/wiley/genetic-studies-on-hybrid-populations-i-individual-estimates-of-7NKZW0WWsa

References (17)

Publisher
Wiley
Copyright
Copyright © 1973 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1111/j.1469-1809.1973.tb00596.x
Publisher site
See Article on Publisher Site

Abstract

Genetic studies on hybrid populations I. Individual estimates of ancestry and their relation to quantitative traits BY CHARLES J. MACLEAN Human Genetics Branch, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20014 PETER L. WORKMAN Division of Medical Genetics, M t Sinai School of Medicine, New York, New York 10029 AND 1NTRODUCTION Any two human populations may be assumed t o differ genetically, in the relative frequencies of alleles present in both populations, and, possibly, in the types of alleles represented a t a locus. For qualitative traits the differences can be demonstrated simply by a comparison of the frequencies of the alleles a t one or more loci. However, for heritable quantitative traits, especially those whose environmental component of variation is in part the result of cultural factors, there appears to be no direct method for interpopulation comparisons. The genes controlling variation in such traits cannot be identified, and the effects of differing physical and cultural environments, the complications of social heredity, and genotype-environment interactions, all make the prospect for such comparisons poor. Thus, as discussed by Thoday (1969), there appears t o be no direct answer to the question of whether there are

Journal

Annals of Human GeneticsWiley

Published: Jan 1, 1973

There are no references for this article.