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General approach for regioselective synthesis of fused phosphono substituted‐oxadiazines

General approach for regioselective synthesis of fused phosphono substituted‐oxadiazines A series of fused 1,3,4‐oxadiazines were regioselectively prepared in reasonable yields as major products from the reactions of the corresponding α‐carbonyl hydrazones with tetraethyl 1,3‐dithietane‐2,4‐diylidene‐bis(cyanomethylphosphonate) (1). Side products were also observed wherein the dimeric products 8 or 17 and/or different types of N‐heterocycles such as pyrazole 24 or pyridazines 28 or 29 were isolated and identified. A comparative study on the chemistry of 1 toward α‐aminonitrile 30 is also described. © 2000 John Wiley & Sons, Inc. Heteroatom Chem 11:196–204, 2000 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Heteroatom Chemistry Wiley

General approach for regioselective synthesis of fused phosphono substituted‐oxadiazines

Heteroatom Chemistry , Volume 11 (3) – Jan 1, 2000

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References (23)

Publisher
Wiley
Copyright
Copyright © 2000 John Wiley & Sons, Inc.
ISSN
1042-7163
eISSN
1098-1071
DOI
10.1002/(SICI)1098-1071(2000)11:3<196::AID-HC6>3.0.CO;2-H
Publisher site
See Article on Publisher Site

Abstract

A series of fused 1,3,4‐oxadiazines were regioselectively prepared in reasonable yields as major products from the reactions of the corresponding α‐carbonyl hydrazones with tetraethyl 1,3‐dithietane‐2,4‐diylidene‐bis(cyanomethylphosphonate) (1). Side products were also observed wherein the dimeric products 8 or 17 and/or different types of N‐heterocycles such as pyrazole 24 or pyridazines 28 or 29 were isolated and identified. A comparative study on the chemistry of 1 toward α‐aminonitrile 30 is also described. © 2000 John Wiley & Sons, Inc. Heteroatom Chem 11:196–204, 2000

Journal

Heteroatom ChemistryWiley

Published: Jan 1, 2000

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