Access the full text.
Sign up today, get DeepDyve free for 14 days.
E. Ziegel (2002)
Generalized Linear ModelsTechnometrics, 44
D. Rabinowitz, N. Laird (2000)
A Unified Approach to Adjusting Association Tests for Population Admixture with Arbitrary Pedigree Structure and Arbitrary Missing Marker InformationHuman Heredity, 50
D. Falush, M. Stephens, J. Pritchard (2003)
Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies.Genetics, 164 4
A. Morris, J. Whittaker, R. Curnow (1997)
A likelihood ratio test for detecting patterns of disease‐marker associationAnnals of Human Genetics, 61
M. Boehnke, C. Langefeld (1998)
Genetic association mapping based on discordant sib pairs: the discordant-alleles test.American journal of human genetics, 62 4
R. Spielman, W. Ewens (1998)
A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test.American journal of human genetics, 62 2
(1999)
c) Using exact p values to compare the power between the RCTDT and the STDT
P. Sham, D. Curtis (1995)
Monte Carlo tests for associations between disease and alleles at highly polymorphic lociAnnals of Human Genetics, 59
J. Pritchard, M. Stephens, N. Rosenberg, P. Donnelly (2000)
Association mapping in structured populations.American journal of human genetics, 67 1
J. Pritchard, Matthew Stephens, P. Donnelly (2000)
Inference of population structure using multilocus genotype data.Genetics, 155 2
P. Sham, D. Curtis (1995)
An extended transmission/disequilibrium test (TDT) for multi‐allele marker lociAnnals of Human Genetics, 59
R. Curnow, Andrew Morris, John Whittaker (2002)
Locating genes involved in human diseasesJournal of the Royal Statistical Society: Series C (Applied Statistics), 47
(1997)
Genomewide TDT testing – consideration of the genotypic relative risks at disease loci
Daniel Rabinowitz (1997)
A transmission disequilibrium test for quantitative trait loci.Human heredity, 47 6
N. Lazar (2003)
Statistical Analysis With Missing DataTechnometrics, 45
I. Tu, A. Whittemore (1999)
Power of association and linkage tests when the disease alleles are unobserved.American journal of human genetics, 64 2
D. Fulker, D. Fulker, S. Cherny, S. Cherny, P. Sham, J. Hewitt (1999)
Combined linkage and association sib-pair analysis for quantitative traits.American journal of human genetics, 64 1
G. Abecasis, L. Cardon, W. Cookson (2000)
A general test of association for quantitative traits in nuclear families.American journal of human genetics, 66 1
S. Self, G. Longton, K. Kopecky, K. Liang (1991)
On estimating HLA/disease association with application to a study of aplastic anemia.Biometrics, 47 1
Genetic Analysis Workshop 11 : Analysis of genetic and environmental factors in common diseases
M. Bass, Norman Kaplan
Letter to the Editor Correcting for a Potential Bias in the Pedigree Disequilibrium Test
G. Abecasis, W. Cookson, L. Cardon (2000)
Pedigree tests of transmission disequilibriumEuropean Journal of Human Genetics, 8
D. Schaid, D. Schaid, Charles Rowland (1998)
Use of parents, sibs, and unrelated controls for detection of associations between genetic markers and disease.American journal of human genetics, 63 5
D. Curtis (1997)
Use of siblings as controls in case‐control association studiesAnnals of Human Genetics, 61
E. Martin, E. Martin, N. Kaplan, B. Weir (1997)
Tests for linkage and association in nuclear families.American journal of human genetics, 61 2
D. Schaid (1996)
General score tests for associations of genetic markers with disease using cases and their parentsGenetic Epidemiology, 13
M. McPeek, A. Strahs (1999)
Assessment of linkage disequilibrium by the decay of haplotype sharing, with application to fine-scale genetic mapping.American journal of human genetics, 65 3
R. Spielman, W. Ewens (1996)
The TDT and other family-based tests for linkage disequilibrium and association.American journal of human genetics, 59 5
J. Whittaker, A. Morris, R. Curnow (1998)
Using information from both parents when testing for association between marker and disease lociGenetic Epidemiology, 15
K. Lunetta, S. Faraone, S. Faraone, J. Biederman, N. Laird (2000)
Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions.American journal of human genetics, 66 2
Bobby Koeleman, Frank Dudbridge, Heather Cordell, John Todd (2000)
Adaptation of the extended transmission/disequilibrium test to distinguish disease associations of multiple loci: the Conditional Extended Transmission/Disequilibrium TestAnnals of Human Genetics, 64
B. Devlin, K. Roeder (1999)
Genomic Control for Association StudiesBiometrics, 55
(2000)
Association tests in incomplete families
D. Clayton (1999)
A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission.American journal of human genetics, 65 4
E. Martin, S. Monks, Liling Warren, N. Kaplan (2000)
A test for linkage and association in general pedigrees: the pedigree disequilibrium test.American journal of human genetics, 67 1
(1999)
Power comparisons of the TDT and Sib - TDT statistics
D. Allison, Moonseong Heo, N. Kaplan, E. Martin (1999)
Sibling-based tests of linkage and association for quantitative traits.American journal of human genetics, 64 6
Michael Knapp (1999)
The transmission/disequilibrium test and parental-genotype reconstruction: the reconstruction-combined transmission/ disequilibrium test.American journal of human genetics, 64 3
Andrew Morris, John Whittaker, David Balding (2000)
Bayesian fine-scale mapping of disease loci, by hidden Markov models.American journal of human genetics, 67 1
S. Monks, N. Kaplan, B. Weir (1998)
A comparative study of sibship tests of linkage and/or association.American journal of human genetics, 63 5
D. Schaid (1998)
Transmission disequilibrium, family controls, and great expectations.American journal of human genetics, 63 4
(1999)
b) A note on power approximations for the TDT
H. Bickeböller, F. Clerget-Darpoux (1995)
Statistical properties of the allelic and genotypic transmission/disequilibrium test for multiallelic markersGenetic Epidemiology, 12
Pak Sham, S. Cherny, Shaun Purcell, John Hewitt (2000)
Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sibship data.American journal of human genetics, 66 5
D. Schaid (1999)
Likelihoods and TDT for the case‐parents designGenetic Epidemiology, 16
(1993)
Transmission test for linkage disequilibrium : the insulin gene region and insulin diabetes mellitus
S. Horvath, N. Laird (1998)
A discordant-sibship test for disequilibrium and linkage: no need for parental data.American journal of human genetics, 63 6
J. Terwilliger (1995)
A powerful likelihood method for the analysis of linkage disequilibrium between trait loci and one or more polymorphic marker loci.American journal of human genetics, 56 3
A. Morris, J. Whittaker (1999)
Generalization of the extended transmission disequilibrium test to two unlinked disease lociGenetic Epidemiology, 17
Xiaofeng Zhu, R. Elston (2001)
Transmission/disequilibrium tests for quantitative traitsGenetic Epidemiology, 20
The large literature on family‐based tests of association and/or linkage is reviewed, concentrating on the underlying principles and on recent methodological developments. We explain the distinction between testing for association and testing for linkage, and give our views on the circumstances in which each is the appropriate null hypothesis.
Annals of Human Genetics – Wiley
Published: Jan 1, 2001
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.