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Evidence‐Based Medicine from Cochrane Library

Evidence‐Based Medicine from Cochrane Library Folate for depressive disorders This systematic review was undertaken to see if giving folate to people with depressive disorders reduced their depressive symptoms. Three randomized trials were identified, involving a total of 247 people. In all three trials, folate was well tolerated. In two of these trials, folate was added to other antidepressant drug treatment and there was limited evidence that folate helped. In the third trial, folate was compared to trazodone, an antidepressant drug. No difference was found. There is therefore limited evidence that adding folate to other antidepressant may be helpful, but larger trials are needed before patients and clinicians can be confident that it will be helpful. Taylor MJ, Carney SM, Geddes J, Goodwin G. Folate for depressive disorders. Cochrane Database of Systematic Reviews 2003, Issue 2. Art. No.: CD003390. DOI: 10.1002/14651858.CD003390 . Psychological and/or educational interventions for the prevention of depression in children and adolescents Depression is common and has a major impact on the functioning of young people who develop depressive disorder. Concern about this has led to the development of a number of depression prevention programmes around the world. The aim of this review was to assess the effectiveness of such intervention http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Asia-Pacific Psychiatry Wiley

Evidence‐Based Medicine from Cochrane Library

Asia-Pacific Psychiatry , Volume 2 (2) – Jun 1, 2010

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References (2)

Publisher
Wiley
Copyright
© 2010 Blackwell Publishing Asia Pty Ltd
ISSN
1758-5864
eISSN
1758-5872
DOI
10.1111/j.1758-5872.2010.00071.x
Publisher site
See Article on Publisher Site

Abstract

Folate for depressive disorders This systematic review was undertaken to see if giving folate to people with depressive disorders reduced their depressive symptoms. Three randomized trials were identified, involving a total of 247 people. In all three trials, folate was well tolerated. In two of these trials, folate was added to other antidepressant drug treatment and there was limited evidence that folate helped. In the third trial, folate was compared to trazodone, an antidepressant drug. No difference was found. There is therefore limited evidence that adding folate to other antidepressant may be helpful, but larger trials are needed before patients and clinicians can be confident that it will be helpful. Taylor MJ, Carney SM, Geddes J, Goodwin G. Folate for depressive disorders. Cochrane Database of Systematic Reviews 2003, Issue 2. Art. No.: CD003390. DOI: 10.1002/14651858.CD003390 . Psychological and/or educational interventions for the prevention of depression in children and adolescents Depression is common and has a major impact on the functioning of young people who develop depressive disorder. Concern about this has led to the development of a number of depression prevention programmes around the world. The aim of this review was to assess the effectiveness of such intervention

Journal

Asia-Pacific PsychiatryWiley

Published: Jun 1, 2010

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