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P. Juto, B. Fredrikzon, O. Hernell (1985)
Gliadin‐Specific Serum Immunoglobulins A, E, G, and M in Childhood: Relation to Small Intestine Mucosal MorphologyJournal of Pediatric Gastroenterology and Nutrition, 4
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Some characteristics of immunofluorescence tests for antibodies against gluten, using wheat grain sections or gliadin coated sepharose beads.Acta pathologica et microbiologica Scandinavica. Section C, Immunology, 89 4
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A. Bürgin-Wolff, R. Bertele, R. Berger, H. Gaze, H. Harms, M. Just, S. Khanna, K. Schürmann, E. Signer, D. Tomović (1983)
A reliable screening test for childhood celiac disease: fluorescent immunosorbent test for gliadin antibodies. A prospective multicenter study.The Journal of pediatrics, 102 5
The reliability of antigliadin antibodies of IgA and IgG classes for the diagnosis and follow‐up of coeliac disease was evaluated by ELISA tests. Forty coeliac patients, 41 patients with other gastrointestinal diseases and 50 healthy subjects were studied. IgA antigliadin antibodies were detected in all patients on unrestricted diet and in those on a challenge with a gluten‐containing diet. A low incidence of positivities was found in patients on a gluten free‐diet, while no positivity was found in controls or gastrointestinal patients. IgG determination, in contrast, showed poor specificity. Our data suggest that a positive IgA antigliadin test may be a reliable marker for the presence of active coeliac disease, which should be confirmed by intestinal biopsy; it is, moreover, a good marker for monitoring patients, since elevated values might suggest non‐compliance with the diet.
Pediatric Allergy and Immunology – Wiley
Published: Jun 1, 1991
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