Access the full text.
Sign up today, get DeepDyve free for 14 days.
Peter Burney, C. Summers, S. Chinn, Richard Hooper, R. Ree, Jonas Lidholm (2010)
Prevalence and distribution of sensitization to foods in the European Community Respiratory Health Survey: a EuroPrevall analysisAllergy, 65
Y. Maeda, E. Ono, Y. Fukutomi, M. Taniguchi, K. Akiyama (2008)
Correlations between alder specific IgE and alder-related tree pollen specific IgE by RAST method.Allergology international : official journal of the Japanese Society of Allergology, 57 1
H. Brough, A. Liu, S. Sicherer, Kerry Makinson, A. Douiri, S. Brown, A. Stephens, W. McLean, V. Turcanu, R. Wood, S. Jones, W. Burks, P. Dawson, D. Stablein, H. Sampson, G. Lack (2015)
Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergyThe Journal of Allergy and Clinical Immunology, 135
F. Codreanu, Olivier Collignon, O. Roitel, B. Thouvenot, C. Sauvage, A. Vilain, M. Cousin, A. Decoster, J. Renaudin, C. Astier, J. Monnez, Pierre Vallois, M. Morisset, D. Moneret-vautrin, Marie Brulliard, V. Ogier, M. Castelain, G. Kanny, B. Bihain, S. Jacquenet (2010)
A Novel Immunoassay Using Recombinant Allergens Simplifies Peanut Allergy DiagnosisInternational Archives of Allergy and Immunology, 154
J. Koplin, R. Peters, A. Ponsonby, L. Gurrin, D. Hill, M. Tang, S. Dharmage, K. Allen (2014)
Increased risk of peanut allergy in infants of Asian‐born parents compared to those of Australian‐born parentsAllergy, 69
Gray (2014)
Food sensitization and allergy in South African children with atopic dermatitisPediatr Allergy Immunol, 25
Krause (2009)
Lipid transfer protein (Ara h 9) as a new peanut allergen relevant for a Mediterranean allergic populationJ Allergy Clin Immunol, 124
C. Venter, C. Venter, B. Pereira, K. Voigt, J. Grundy, C. Clayton, C. Gant, B. Higgins, T. Dean, T. Dean (2007)
Comparison of open and double-blind placebo-controlled food challenges in diagnosis of food hypersensitivity amongst children.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 20 6
H. Bernard, B. Guillon, M. Drumare, E. Paty, S. Dreskin, J. Wal, K. Adel‐Patient, S. Hazebrouck (2015)
Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes.The Journal of allergy and clinical immunology, 135 5
S. Koppelman, M. Wensing, M. Ertmann, A. Knulst, Edward Knol (2004)
Relevance of Ara h1, Ara h2 and Ara h3 in peanut‐allergic patients, as determined by immunoglobulin E Western blotting, basophil–histamine release and intracutaneous testing: Ara h2 is the most important peanut allergenClinical & Experimental Allergy, 34
W. Chiang, L. Pons, M. Kidon, W. Liew, A. Goh, A. Burks (2010)
Serological and clinical characteristics of children with peanut sensitization in an Asian communityPediatric Allergy and Immunology, 21
C. Agabriel, Ouafeh Ghazouani, J. Birnbaum, V. Liabeuf, F. Porri, M. Gouitaa, I. Cleach, J. Grob, P. Bongrand, J. Sarles, J. Vitte (2014)
Ara h 2 and Ara h 6 sensitization predicts peanut allergy in Mediterranean pediatric patientsPediatric Allergy and Immunology, 25
J. Koplin, S. Dharmage, A. Ponsonby, M. Tang, A. Lowe, L. Gurrin, N. Osborne, P. Martin, M. Robinson, M. Wake, D. Hill, K. Allen (2012)
Environmental and demographic risk factors for egg allergy in a population‐based study of infantsAllergy, 67
A. Branum, Susan Lukacs (2009)
Food Allergy Among Children in the United StatesPediatrics, 124
J. Grundy, S. Matthews, B. Bateman, T. Dean, S. Arshad (2002)
Rising prevalence of allergy to peanut in children: Data from 2 sequential cohorts.The Journal of allergy and clinical immunology, 110 5
H. Sampson (2001)
Utility of food-specific IgE concentrations in predicting symptomatic food allergy.The Journal of allergy and clinical immunology, 107 5
A. Amoah, B. Obeng, I. Larbi, S. Versteeg, Y. Aryeetey, J. Akkerdaas, L. Zuidmeer, J. Lidholm, M. Fernández-Rivas, F. Hartgers, D. Boakye, R. Ree, M. Yazdanbakhsh (2013)
Peanut-specific IgE antibodies in asymptomatic Ghanaian children possibly caused by carbohydrate determinant cross-reactivityThe Journal of Allergy and Clinical Immunology, 132
N. Nicolaou, C. Murray, D. Belgrave, M. Poorafshar, A. Simpson, A. Custovic (2011)
Quantification of specific IgE to whole peanut extract and peanut components in prediction of peanut allergy.The Journal of allergy and clinical immunology, 127 3
A. Asarnoj, R. Movérare, E. Östblom, E. Östblom, M. Poorafshar, G. Lilja, G. Hedlin, G. Hedlin, M. Hage, Staffan Ahlstedt, M. Wickman, M. Wickman (2010)
IgE to peanut allergen components: relation to peanut symptoms and pollen sensitization in 8‐year‐oldsAllergy, 65
P. Eigenmann, A. Calza (2000)
Diagnosis of IgE‐mediated food allergy among Swiss children with atopic dermatitisPediatric Allergy and Immunology, 11
I. Dalal, Inga Binson, R. Reifen, Z. Amitai, T. Shohat, S. Rahmani, A. Levine, A. Ballin, E. Somekh (2002)
Food allergy is a matter of geography after all: sesame as a major cause of severe IgE‐mediated food allergic reactions among infants and young children in IsraelAllergy, 57
(2015)
Health-related quality of life among Table 3 Comparison of use of widely used 95% positive predictive values (PPVs) in Xhosa vs. mixed race patients
B. Marklund, Staffan Ahlstedt, G. Nordström (2004)
Health-related quality of life among adolescents with allergy-like conditions – with emphasis on food hypersensitivityHealth and Quality of Life Outcomes, 2
R. Peters, K. Allen, S. Dharmage, M. Tang, J. Koplin, A. Ponsonby, A. Lowe, D. Hill, L. Gurrin
Food , drug , insect sting allergy , and anaphylaxis Skin prick test responses and allergen-specific IgE levels as predictors of peanut , egg , and sesame allergy in infants
A. Burks, J. James, Anne Hiegel, G. Wilson, J. Wheeler, S. Jones, N. Zuerlein (1998)
Atopic dermatitis and food hypersensitivity reactions.The Journal of pediatrics, 132 1
C. Venter, S. Arshad, J. Grundy, B. Pereira, C. Clayton, K. Voigt, B. Higgins, T. Dean, T. Dean (2010)
Time trends in the prevalence of peanut allergy: three cohorts of children from the same geographical location in the UKAllergy, 65
S. Krause, G. Reese, S. Randow, D. Zennaro, D. Quaratino, P. Palazzo, M. Ciardiello, A. Petersen, W. Becker, A. Mari
Food , drug , insect sting allergy , and anaphylaxis Lipid transfer protein ( Ara h 9 ) as a new peanut allergen relevant for a Mediterranean allergic population
M. Ebisawa, R. Movérare, Sakura Sato, M. Borres, Komei Ito (2015)
The predictive relationship between peanut- and Ara h 2-specific serum IgE concentrations and peanut allergy.The journal of allergy and clinical immunology. In practice, 3 1
R. Sporik, David Hill, C. Hosking (2000)
Specificity of allergen skin testing in predicting positive open food challenges to milk, egg and peanut in childrenClinical & Experimental Allergy, 30
W. Basera, Maresa Botha, C. Gray, N. Lunjani, A. Watkins, C. Venter, K. Allen, C. Hlela, H. Zar, M. Levin (2015)
The South African Food Sensitisation and Food Allergy population-based study of IgE-mediated food allergy: validity, safety, and acceptability.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 115 2
A. Vereda, M. Hage, S. Ahlstedt, M. Ibáñez, J. Cuesta-Herranz, J. Odijk, M. Wickman, H. Sampson (2011)
Peanut allergy: Clinical and immunologic differences among patients from 3 different geographic regions.The Journal of allergy and clinical immunology, 127 3
Peters (2013)
Skin Prick test responses and allergen-specific IgE levels as predictors of peanut, egg and sesame allergy in infantsJ Allergy Clin Immunol, 132
X. Hong, D. Caruso, R. Kumar, R. Liu, X. Liu, G. Wang, J. Pongracic, X. Wang (2012)
IgE, but not IgG4, antibodies to Ara h 2 distinguish peanut allergy from asymptomatic peanut sensitizationAllergy, 67
Kirsten Beyer, Kirsten Beyer, Linus Grabenhenrich, M. Härtl, A. Beder, B. Kalb, M. Ziegert, A. Finger, N. Harandi, R. Schlags, M. Gappa, L. Puzzo, H. Röblitz, M. Millner-Uhlemann, S. Büsing, H. Ott, Lars Lange, B. Niggemann, B. Niggemann (2015)
Predictive values of component‐specific IgE for the outcome of peanut and hazelnut food challenges in childrenAllergy, 70
C. Keet, R. Wood, E. Matsui (2012)
Limitations of reliance on specific IgE for epidemiologic surveillance of food allergy.The Journal of allergy and clinical immunology, 130 5
G. Toit, M. Levin, C. Motala, M. Perkin, A. Stephens, V. Turcanu, G. Lack (2007)
Peanut Allergy and Peanut-specific IgG4 characteristics among Xhosa Children in Cape TownThe Journal of Allergy and Clinical Immunology, 119
M. Ebisawa, R. Movérare, Sakura Sato, N. Maruyama, M. Borres, T. Komata (2012)
Measurement of Ara h 1‐, 2‐, and 3‐specific IgE antibodies is useful in diagnosis of peanut allergy in Japanese childrenPediatric Allergy and Immunology, 23
Background The prevalence of peanut allergy in South Africa is unknown, but previously thought to be low, particularly in black South Africans. This study aimed to determine the prevalence of component patterns and predictive values of screening tests in peanut allergy in South African children with atopic dermatitis (AD). Methodology This was a prospective, observational study in a pediatric university hospital in Cape Town. Children with AD, aged 6 months to 10 years, were recruited randomly. They were assessed for sensitization and allergy to peanut by questionnaire, skin prick tests (SPT), Immuno Solid Phase Allergen Chip test, ImmunoCAP component tests to Ara h 1, 2, 3, 8, and 9, and incremental food challenges. Results A total of 100 participants (59 black Africans and 41 of mixed race) were enrolled, median age 42 months. There was a high and comparable rate of peanut sensitization in both black African (41%) and mixed race patients (50%), but a significantly lower prevalence of peanut allergy in the black African group (15% vs. 38%, p = 0.01). The component Ara h 2 was the most useful in differentiating allergy from tolerance in both ethnic groups, but had a significantly lower predictive value for peanut allergy in blacks (53%) vs. mixed race (93%). Overall, SPT and Ara h 2 produced the highest area under the receiver operating characteristic curve. A total of 95% positive predictive values (PPV) for SPT, peanut‐specific IgE, and Ara h 2 levels varied significantly between the two ethnic groups. Conclusion The prevalence of peanut allergy is high in South African children with AD, but significantly lower in blacks compared to mixed race patients. The component Ara h 2 is useful for differentiating allergy from tolerance in both ethnic groups. Ninety‐five% PPV for peanut allergy tests may need to be revised by ethnic group.
Pediatric Allergy and Immunology – Wiley
Published: Dec 1, 2015
Keywords: ; ; ; ; ; ; ;
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.