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C. Arrigo, H. Gall, A. Delogne, C. Molin (1994)
The involvement of nurses in clinical trials; Results of the EORTC Oncology Nurses Study Group surveyCancer Nursing, 17
H Sutherland, G Lockwood, J. Till (1990)
Are We Getting Informed Consent from Patients with Cancer?Bioethics News, 11
M. Markman (1986)
Opinion: The ethical dilemma of phase i clinical trialsCA: A Cancer Journal for Clinicians, 36
H. Muss, D. White, R. Michielutte, F. Richards, M. Cooper, Sarah Williams, J. Stuart, C. Spurr (1979)
Written informed consent in patients with breast cancerCancer, 43
R. Fox (1981)
SITUATIONS CREATING ETHICAL STRESSMedical Journal of Australia, 1
K. Cox, A. Bergen, I. Norman (1993)
Exploring consumer views of care provided by the Macmillan nurse using the critical incident technique.Journal of advanced nursing, 18 3
S. Waterworth, K. Luker (1990)
Reluctant collaborators: do patients want to be involved in decisions concerning care?Journal of advanced nursing, 15 8
R. Soller, H. Stander (1983)
Association between salicylates and Reye's syndrome.JAMA, 249 7
B. Freedman (1990)
Cohort-specific consent: an honest approach to phase 1 clinical cancer studies.IRB, 12 1
WHO Chronicle, 1
L. Degner (1992)
Patient participation in treatment decision making.Axone, 14 1
M. Silva, J. Sorrell (1984)
Factors influencing comprehension of information for informed consent: ethical implications for nursing research.International journal of nursing studies, 21 4
A. Jensen, B. Madsen, Poula Andersen, C. Rose (1993)
Information for cancer patients entering a clinical trial--an evaluation of an information strategy.European journal of cancer, 29A 16
Eric Kodish, C. Stocking, M. Ratain, A. Kohrman, Mark Siegler (1992)
Ethical issues in phase I oncology research: a comparison of investigators and institutional review board chairpersons.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 10 11
Arrigo Arrigo, Gall Gall, Delogne Delogne (1994)
The involvement of nurses in clinical trialsCancer Nursing, 17
N. Kemp, E. Skinner, J. Toms (1984)
Randomized clinical trials of cancer treatment--a public opinion survey.Clinical oncology, 10 2
W. Strull, B. Lo, G. Charles (1984)
Do patients want to participate in medical decision making?JAMA, 252 21
B. Cassileth, E. Lusk, D. Miller, S. Hurwitz (1982)
Attitudes toward clinical trials among patients and the public.JAMA, 248 8
M. Calnan (1988)
Towards a conceptual framework of lay evaluation of health care.Social science & medicine, 27 9
M. Mattson, J. Curb, R. McArdle (1985)
Participation in a clinical trial: the patients' point of view.Controlled clinical trials, 6 2
V. Herbert (1980)
Informed consent—a legal evaluationCancer, 46
Maslin Maslin, Powles Powles, Baum Baum, Ashley Ashley, Tidy Tidy (1993)
A survey of the opinions on ‘informed consent’ of women attending a breast unitEuropean Journal of Cancer, 29A
M. Ratain, R. Mick, R. Schilsky, M. Siegler (1993)
Statistical and ethical issues in the design and conduct of phase I and II clinical trials of new anticancer agents.Journal of the National Cancer Institute, 85 20
B. Cassileth, R. Zupkis, K. Sutton-Smith, V. March (1980)
Information and participation preferences among cancer patients.Annals of internal medicine, 92 6
Dan Brock, S. Wartman (1990)
When competent patients make irrational choices.The New England journal of medicine, 322 22
N. Lynøe, M. Sandlund, Gisela Dahlqvist, L. Jacobsson (1991)
Informed consent: study of quality of information given to participants in a clinical trial.British Medical Journal, 303
M. Zwitter, CJ Williams (1993)
Informed consent in european multicentric randomised clinical trialsEuropean Journal of Cancer, 29
R. Rubens, K. Towlson, A. Ramirez, S. Coltart, M. Slevin, C. Terrell, A. Timothy (1992)
Appropriate chemotherapy for palliating advanced cancer.British Medical Journal, 304
G. Schwartsmann, J. Wanders, I. Koier, H. Franklin, O. Dalesio, H. Hornstra, M. Glabbeke, J. Renard, A. Oosterom, S. Kaye (1991)
EORTC New Drug Development Office coordinating and monitoring programme for phase I and II trials with new anticancer agents.European journal of cancer, 27 9
M. Kirby (1983)
Informed consent: what does it mean?Journal of Medical Ethics, 9
Meade Cd, Howser Dm (1992)
Consent forms: how to determine and improve their readability.Oncology nursing forum, 19 10
Markman Markman (1986)
The ethical dilemma of Phase I clinical trialsCA-A cancer Journal for Clinicians, 36
M. Lipsett (1982)
On the nature and ethics of phase I clinical trials of cancer chemotherapies.JAMA, 248 8
S. Rodenhuis, W. Heuvel, A. Annyas, H. Koops, D. Sleijfer, N. Mulder (1984)
Patient motivation and informed consent in a phase I study of an anticancer agent.European journal of cancer & clinical oncology, 20 4
Kemp Kemp, Skinner Skinner (1984)
Randomized control trials in cancer treatment‐a public opinion surveyClinical Oncology, 10
M. Avis (1994)
Choice cuts: an exploratory study of patients' views about participation in decision-making in a day surgery unit.International journal of nursing studies, 31 3
C. Gotay (1991)
Accrual to cancer clinical trials: directions from the research literature.Social science & medicine, 33 5
H. Sutherland, H. Llewellyn-Thomas, G. Lockwood, D. Tritchler, J. Till (1989)
Cancer Patients: Their Desire for Information and Participation in Treatment DecisionsJournal of the Royal Society of Medicine, 82
G. Mead, C. Williams (1991)
Developing new drugs for cancer.British Medical Journal, 303
A. Beisecker, Thomas Beisecker (1990)
Patient Information-Seeking Behaviors When Communicating With DoctorsMedical Care, 28
Sutherland Sutherland, Lockwood Lockwood, Till Till (1990)
Are we getting informed consent from patients with cancerJournal of the Royal Society of Medicine, 83
Rick Street (1991)
Information-giving in medical consultations: the influence of patients' communicative styles and personal characteristics.Social science & medicine, 32 5
Kodish Kodish, Stocking Stocking, Ratain Ratain, Kohrman Kohrman, Siegler Siegler (1992)
Ethical issues in Phase I oncology research: a comparison of investigators and review board chairpersonsJournal of Clinical Oncology, 10
L. Fallowfield, A. Hall, G. Maguire, M. Baum (1990)
Psychological outcomes of different treatment policies in women with early breast cancer outside a clinical trial.British Medical Journal, 301
J. Tobias, J. Houghton (1994)
Is informed consent essential for all chemotherapy studies?European journal of cancer, 30A 7
D. Penman, J. Holland, G. Bahna, G. Morrow, Arthur Schmale, L. Derogatis, C. Carnrike, R. Cherry (1984)
Informed consent for investigational chemotherapy: patients' and physicians' perceptions.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2 7
R. Simes, M. Tattersall, A. Coates, D. Raghavan, H. Solomon, H. Smartt (1986)
Randomised comparison of procedures for obtaining informed consent in clinical trials of treatment for cancer.British Medical Journal (Clinical research ed.), 293
Mead Mead, Williams Williams (1991)
Developing new drugs for cancer: clinical science or unfettered marketBritish Medical Journal, 303
K. Taylor, M. Kelner (1987)
Informed consent: the physicians' perspective.Social science & medicine, 24 2
J. Lantos (1993)
Informed consent the whole truth for patients?Cancer, 72
Carr‐Hill Carr‐Hill (1992)
The measurement of patient satisfactionJournal of Public Health Medicine, 14
Barofsky Barofsky, Sugarbaker Sugarbaker (1979)
Determinants of patient nonparticipation in randomized clinical trials for the treatment of sarcomasCancer Clinical Trials, 2
Lipsett Lipsett (1983)
Ethics of phase I clinical trials (Letters)Journal of the American Medical Association, 249
B. Cassileth, R. Zupkis, K. Sutton-Smith, V. March (1980)
Informed consent -- why are its goals imperfectly realized?The New England journal of medicine, 302 16
J. Cassidy, D. Macfarlane (1991)
The role of the nurse in clinical cancer researchCancer Nursing, 14
Early clinical trials for new anti‐cancer drug treatments typically use patients with cancer as research subjects. This paper identifies some of the ethical and practical concerns that arise from the recruitment of a vulnerable group of patients and their exposure to a drug of unknown risk or benefit. This review discusses the ethical principles related to recruitment and informed consent in cancer trials, and indicates that there is a lack of consensus concerning the requirements, process and practice of informed consent. It is suggested that, as yet, little is know about patients' decision making framework in this situation, and the need for further work that concentrates on the patient's point of view is highlighted. The paper concludes by discussing some of the difficulties associated with obtaining patients’opinions, and suggests that the use of a qualitative approach may overcome some of these problems.
European Journal of Cancer Care – Wiley
Published: Jun 1, 1996
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