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Implantable cardioverter/defibrillators have been highly effective in the prevention of recurrent sudden arrhythmic death in patients resuscitated from cardiac arrest or recurrent ventricular tachyarrhythmias.' Clinical studies have determined that the incidence of sudden cardiac death is reduced to 2%-5% a n n ~ a l l y .The presently approved car~,~ dioverter/defibrillator system includes an implantable pulse generator placed in an abdominal pocket and an epicardial electrode system. The epicardial electrode system involves one or more epicardial leads and is associated with a significant perioperative mortality or morbidity. The latter is largely related to the need for a major surgical procedure, i.e., a thoracotomy, in these patients, who usually have significant cardiac disease. Patients who present with sudden cardiac death or recurrent ventricular tachyarrhythmias are often elderly and have a variety of noncardiac disorders that increase the risk ofa thoracotomy. Perioperative mortality has ranged from 0%-9% in different experiences. The need for major surgery has restricted the use of implantable cardioverter/defibrillator therapy to major centers with capabilities for this type of procedure. Patient and physician acceptance of this surgical technique has been somewhat limited. Due to these concerns, experimental and clinical studies have been undertaken to develop a
Journal of Interventional Cardiology – Wiley
Published: Mar 1, 1990
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