Access the full text.
Sign up today, get DeepDyve free for 14 days.
A. Schreiber, T. Libermann, I. Lax, Y. Yarden, J. Schlessinger (1983)
Biological role of epidermal growth factor-receptor clustering. Investigation with monoclonal anti-receptor antibodies.The Journal of biological chemistry, 258 2
Celiac spruce
Dermatitis herpetifomis
L. Sollid, E. Thorsby (1993)
HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis.Gastroenterology, 105 3
SJÖLANDER SJÖLANDER, MAGNUSSON MAGNUSSON, LATCOVIC LATCOVIC (1984)
The effect of concanavalin A and wheat germ agglutinin on the ultra‐structure and permeability of rat intestineInt Arch All Appl Immunol, 75
J. Kolberg, L. Sollid (1985)
Lectin activity of gluten identified as wheat germ agglutinin.Biochemical and biophysical research communications, 130 2
S. Auricchio, G. Ritis, M. Vincenzi, G. Magazzù, L. Maiuri, E. Mancini, M. Minetti, O. Sapora, V. Silano (1990)
Mannan and oligomers of N-acetylglucosamine protect intestinal mucosa of celiac patients with active disease from in vitro toxicity of gliadin peptides.Gastroenterology, 99 4
MCNEISH MCNEISH, HARMS HARMS, REY REY, SHMERLING SHMERLING, VISA‐KORPI VISA‐KORPI, WALKER‐SMITH WALKER‐SMITH (1979)
The diagnosis of coeliac diseaseArch Di's Child, 54
I. Goldstein, R. Hughes, M. Monsigny, T. Osawa, N. Sharon (1980)
What should be called a lectin?Nature, 285
BARRESI BARRESI, TUCCARI TUCCARI, TEDESCHI TEDESCHI (1988)
MAGAZZU G. Lectin binding sites in duodenojejunal mucosae from coeliac childrenHistochemistry, 88
M. Weiser, A. Douglas (1976)
AN ALTERNATIVE MECHANISM FOR GLUTEN TOXICITY IN CŒLIAC DISEASEThe Lancet, 307
(1988)
Distinct patterns of granulocyte luminol-dependent chemiluminiscence response to lectins WGA and RCA-I. Inflammation
K. Fälth‐magnusson, H. Öman, N. Kjellman (1987)
Maternal abstention from cow milk and egg in allergy risk pregnanciesAllergy, 42
G. Hillman, J. Schlessinger (1982)
Lateral diffusion of epidermal growth factor complexed to its surface receptors does not account for the thermal sensitivity of patch formation and endocytosis.Biochemistry, 21 7
M. Marsh (1992)
Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue').Gastroenterology, 102 1
Gliadin - specific , HLA - DQ ( alfa 1 * 0501 , f 31 * 020 1 ) restricted T cells isolated from the small intestine of celiac disease patients
E. Köttgen, M. Beiswenger, L. James, C. Bauer (1988)
In vivo induction of gliadin-mediated enterocyte damage in rats by the mannosidase inhibitor, swainsonine: a possible animal model for celiac disease.Gastroenterology, 95 1
Morphologic changes of rat small intestine after short - time exposure to concanavalin A or wheat germ agglutinin
K. Lundin, H. Scott, T. Hansen, G. Paulsen, T. Halstensen, O. Fausa, E. Thorsby, L. Sollid (1993)
Gliadin-specific, HLA-DQ(alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patientsThe Journal of Experimental Medicine, 178
I. Goldstein, R. Poretz (1986)
2 – Isolation, Physicochemical Characterization, and Carbohydrate-Binding Specificity of Lectins
(1982)
Lateral diffusion of epidermal growth factor complexed to its surface does not account for the thermal sensitivity of patch formation and endocyto
(1988)
Lectin binding sites in duodeno - jejunal rnucosae from coeliac children
SCHREIBER SCHREIBER, LIBERMANN LIBERMANN, LAX LAX, YARDEN YARDEN (1983)
SCHLESSINGER J. Biological role of epidermal growth factor‐receptor clustering: investigation with monoclonal receptor antibodiesJ Biol Chem, 258
(1988)
IgA and IgM to food antigens during the first 18 months of life in relation to feeding and development of atopic symptoms
Y. Yarden, J. Schlessinger (2008)
The EGF receptor kinase: evidence for allosteric activation and intramolecular self-phosphorylation.Ciba Foundation symposium, 116
A. Sjölander, K. Magnusson, S. Latkovic (1984)
The effect of concanavalin A and wheat germ agglutinin on the ultrastructure and permeability of rat intestine. A possible model for an intestinal allergic reaction.International archives of allergy and applied immunology, 75 3
GOLDSTEIN GOLDSTEIN, HUGHES HUGHES, MONSIGNY MONSIGNY, OSAWA OSAWA (1980)
SHARON NWhat should be called a lectin? Nature, 285
V. Lorenzsonn, W. Olsen (1982)
In vivo responses of rat intestinal epithelium to intraluminal dietary lectins.Gastroenterology, 82 5 Pt 1
MAGNUSSON MAGNUSSON, DAHLGREN DAHLGREN, SJÖLANDER SJÖLANDER (1988)
Distinct patterns of granulocyte luminol‐dependent chemilumi‐niscence response to lectins WGA and RCA‐1Inflammation, 12
M. Weinman, C. Allan, J. Trier, S. Hagen (1989)
Repair of microvilli in the rat small intestine after damage with lectins contained in the red kidney bean.Gastroenterology, 97 5
K. Fälth‐magnusson, N. Kjellman, K. Magnusson (1988)
Antibodies IgG, IgA, and IgM to food antigens during the first 18 months of life in relation to feeding and development of atopic disease.The Journal of allergy and clinical immunology, 81 4
(1987)
risk pregnancies : effect on antibody production in the mother and the newborn
A. Sjölander, K. Magnusson, S. Latkovic (1986)
Morphological changes of rat small intestine after short-time exposure to concanavalin A or wheat germ agglutinin.Cell structure and function, 11 3
KJELLMAN NIM . Maternal abstention from cow ’ s milk and egg in
A. Sjölander, K. Magnusson (1988)
Effects of wheat germ agglutinin on the cellular content of filamentous actin in Intestine 407 cells.European journal of cell biology, 47 1
R. Watson (2005)
Diagnosis of coeliac diseaseBMJ : British Medical Journal, 330
K. Fälth‐magnusson, G. Jansson, L. Stenhammar, K. Magnusson (1994)
Serum Food Antibodies Analyzed by Enzyme‐Linked Immunosorbent Assay (ELISA) and Diffusion‐in-Gel (DIG)-ELISA Methods in Children with and without Celiac DiseaseJournal of Pediatric Gastroenterology and Nutrition, 18
M. Kik, J. Koninkx, A. Muysenberg, F. Hendriksen (1991)
Pathological effects of Phaseolus vulgaris isolectins on pig jejunal mucosa in organ culture.Gut, 32
(1975)
Major problems in dermatology
S. Auricchio, G. Ritis, M. Vincenzi, V. Gentile, L. Maiuri, E. Mancini, R. Porta, V. Raia (1990)
Amines protect in vitro the celiac small intestine from the damaging activity of gliadin peptides.Gastroenterology, 99 6
A. Sjölander (1988)
Direct effects of wheat germ agglutinin on inositol phosphate formation and cytosolic‐free calcium level in intestine 407 cellsJournal of Cellular Physiology, 134
L. Sollid, J. Kolberg, H. Scott, J. Ek, O. Fausa, P. Brandtzaeg (1986)
Antibodies to wheat germ agglutinin in coeliac disease.Clinical and experimental immunology, 63 1
R. Zidovetzki, Y. Yarden, J. Schlessinger, T. Jovin (1981)
Rotational diffusion of epidermal growth factor complexed to cell surface receptors reflects rapid microaggregation and endocytosis of occupied receptors.Proceedings of the National Academy of Sciences of the United States of America, 78 11
A. Mcneish, H. Harms, J. Rey, D. Shmerling, J. Visakorpi, J. Walker-Smith, Haunerschen Kinderspital, Munich Harms, Kinderspital Steinwiesstrasse, Zurich Shmerling (1979)
The diagnosis of coeliac disease. A commentary on the current practices of members of the European Society for Paediatric Gastroenterology and Nutrition (ESPGAN).Archives of Disease in Childhood, 54
(1987)
Maternal abstention from cow's milk and egg in allergy risk pregnancies: effect on antibody production in the mother and the newborn
Lectins recognize carbohydrate moities of glycoproteins and glycolipids, and can elicit several biological effects, including cell agglutination, cell activation and mitogenesis. According to the gluten‐lectin theory, celiac lesions represent a response to a toxic lectin, putatively wheat germ agglutinin (WGA). In this study we compared the serum antibody levels IgA, IgG and IgM to WGA and to gliadin in children under investigation for celiac disease (CD), as compared to reference children. We found that the levels of IgA and IgG to WGA as well as gliadin were significantly higher in celiac children on a gluten‐containing diet, compared to children on gluten‐free diet and reference children. These findings lend support to the concept that WGA is a biologically significant component of gluten. Since WGA can mimic the effects of epidermal growth factor (EGF) at the cellular level, we hypothezise that the crypt hyperplasia seen in celiac children could be due to a mitogenic response induced by WGA.
Pediatric Allergy and Immunology – Wiley
Published: May 1, 1995
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.