Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Do parental smoking and history of allergy influence cord‐serum IgE?

Do parental smoking and history of allergy influence cord‐serum IgE? The associations between parental smoking habits during pregnancy, family history of allergy, and IgE levels in cord‐serum IgE (clgE) were investigated prospectively in 1251 infants. Mean clgE levels were similar in infants with positive and negative family history of allergy (0.50 and 0.54 kU/1, respectively). In infants with a positive family history of allergy whose mothers smoked more than 10 cigarettes a day, however, the mean clgE level was significantly higher (0.78 kU/1) than that in infants of nonsmoking mothers (p = 0.011). Similarly, the mean clgE level was significantly higher in boys (0.61 kU/1) than in girls (0.51 kU/1) of nonsmoking parents (p = 0.03). However, in infants of smoking parents, there was no significant difference in the mean clgE level between boys and girls. A total of 178 (14%) mothers and 477 (38%) fathers were current smokers, and in 128 (10%) cases, both parents were active smokers. The mean clgE level tended to be slightly higher in infants of smoking mothers, especially when the mother consumed more than 10 cigarettes a day (0.63 vs 0.54 kU/1) (p > 0.05). Thus, clgE levels were higher only in genetically prone babies whose mothers consumed more than 10 cigarettes a day. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatric Allergy and Immunology Wiley

Do parental smoking and history of allergy influence cord‐serum IgE?

Download PDF
3 pages

Loading next page...
 
/lp/wiley/do-parental-smoking-and-history-of-allergy-influence-cord-serum-ige-O0C2HTle7E

References (17)

Publisher
Wiley
Copyright
Copyright © 1995 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0905-6157
eISSN
1399-3038
DOI
10.1111/j.1399-3038.1995.tb00288.x
Publisher site
See Article on Publisher Site

Abstract

The associations between parental smoking habits during pregnancy, family history of allergy, and IgE levels in cord‐serum IgE (clgE) were investigated prospectively in 1251 infants. Mean clgE levels were similar in infants with positive and negative family history of allergy (0.50 and 0.54 kU/1, respectively). In infants with a positive family history of allergy whose mothers smoked more than 10 cigarettes a day, however, the mean clgE level was significantly higher (0.78 kU/1) than that in infants of nonsmoking mothers (p = 0.011). Similarly, the mean clgE level was significantly higher in boys (0.61 kU/1) than in girls (0.51 kU/1) of nonsmoking parents (p = 0.03). However, in infants of smoking parents, there was no significant difference in the mean clgE level between boys and girls. A total of 178 (14%) mothers and 477 (38%) fathers were current smokers, and in 128 (10%) cases, both parents were active smokers. The mean clgE level tended to be slightly higher in infants of smoking mothers, especially when the mother consumed more than 10 cigarettes a day (0.63 vs 0.54 kU/1) (p > 0.05). Thus, clgE levels were higher only in genetically prone babies whose mothers consumed more than 10 cigarettes a day.

Journal

Pediatric Allergy and Immunology – Wiley

Published: Nov 1, 1995

There are no references for this article.