Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Distinct neural mechanisms for remembering when an event occurred

Distinct neural mechanisms for remembering when an event occurred ABSTRACT Events are often remembered as having occurred in a specific order, but almost nothing is known about how the brain encodes this temporal information. It is commonly assumed that temporal information is encoded via a single mechanism, based either on the temporal context in which the event occurred or inferred from the strength of the memory trace itself. By analyzing time‐dependent changes in activity patterns, we show that the distinctiveness of contextual representations in the hippocampus and anterior and medial prefrontal cortex was associated with accurate recency memory. In contrast, overall activation in the perirhinal and lateral prefrontal cortices predicted whether an object would be judged more recent, regardless of accuracy. These results demonstrate that temporal information was encoded through at least two complementary neural mechanisms. © 2016 Wiley Periodicals, Inc. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Hippocampus Wiley

Distinct neural mechanisms for remembering when an event occurred

Hippocampus , Volume 26 (5) – May 1, 2016

Loading next page...
 
/lp/wiley/distinct-neural-mechanisms-for-remembering-when-an-event-occurred-awdnbAGuGx

References (53)

Publisher
Wiley
Copyright
© 2016 Wiley Periodicals, Inc.
ISSN
1050-9631
eISSN
1098-1063
DOI
10.1002/hipo.22571
pmid
26845069
Publisher site
See Article on Publisher Site

Abstract

ABSTRACT Events are often remembered as having occurred in a specific order, but almost nothing is known about how the brain encodes this temporal information. It is commonly assumed that temporal information is encoded via a single mechanism, based either on the temporal context in which the event occurred or inferred from the strength of the memory trace itself. By analyzing time‐dependent changes in activity patterns, we show that the distinctiveness of contextual representations in the hippocampus and anterior and medial prefrontal cortex was associated with accurate recency memory. In contrast, overall activation in the perirhinal and lateral prefrontal cortices predicted whether an object would be judged more recent, regardless of accuracy. These results demonstrate that temporal information was encoded through at least two complementary neural mechanisms. © 2016 Wiley Periodicals, Inc.

Journal

HippocampusWiley

Published: May 1, 2016

Keywords: ; ; ; ;

There are no references for this article.