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Determination of isoniazid and hydrazine by capillary electrophoresis with amperometric detection at a Pt‐particle modified carbon fiber microelectrode

Determination of isoniazid and hydrazine by capillary electrophoresis with amperometric detection... Capillary electrophoresis (CE)/electrochemical detection (EC) for the simultaneous determination of hydrazine and isoniazid has been developed. The electrochemical method uses a novel modified electrode dispersed with ultrafine platinum particles on the surface of a 30 μm carbon fiber microelectrode. The unique characteristic of the Pt‐particles modified carbon fiber microelectrode is its excellent stability. The current measurement for hydrazine is more sensitive than that of isoniazid. Selective determination of trace amount of free hydrazine in isoniazid and its formulation can be achieved at applied potential of 0.5 V. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chinese Journal of Chemistry Wiley

Determination of isoniazid and hydrazine by capillary electrophoresis with amperometric detection at a Pt‐particle modified carbon fiber microelectrode

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References (19)

Publisher
Wiley
Copyright
Copyright © 1996 Wiley Subscription Services, Inc., A Wiley Company
ISSN
1001-604X
eISSN
1614-7065
DOI
10.1002/cjoc.19960140207
Publisher site
See Article on Publisher Site

Abstract

Capillary electrophoresis (CE)/electrochemical detection (EC) for the simultaneous determination of hydrazine and isoniazid has been developed. The electrochemical method uses a novel modified electrode dispersed with ultrafine platinum particles on the surface of a 30 μm carbon fiber microelectrode. The unique characteristic of the Pt‐particles modified carbon fiber microelectrode is its excellent stability. The current measurement for hydrazine is more sensitive than that of isoniazid. Selective determination of trace amount of free hydrazine in isoniazid and its formulation can be achieved at applied potential of 0.5 V.

Journal

Chinese Journal of ChemistryWiley

Published: Mar 1, 1996

Keywords: ; ; ; ; ; ;

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