Access the full text.
Sign up today, get DeepDyve free for 14 days.
M. Kaplan, Marion Johnson (1996)
BREASTFEEDING AS PROPHYLAXIS AGAINST ATOPIC DISEASE: PROSPECTIVE FOLLOW-UP STUDY UNTIL 17 YEARS OLDPediatrics
Balvinder Kaur, H. Anderson, J. Austin, M. Burr, L. Harkins, D. Strachan, J. Warner (1998)
Prevalence of asthma symptoms, diagnosis, and treatment in 12–14 year old children across Great Britain (international study of asthma and allergies in childhood, ISAAC UK)BMJ, 316
J. Hopkin (1995)
Genetics of atopyPediatric Allergy and Immunology, 6
R. Chandra, S. Puri, C. Suraiya, P. Cheema (1986)
Influence of maternal food antigen avoidance during pregnancy and lactation on incidence of atopic eczema in infantsClinical & Experimental Allergy, 16
T. Shirakawa, T. Enomoto, S. Shimazu, J. Hopkin (1996)
The Inverse Association Between Tuberculin Responses and Atopic DisorderScience, 275
Christophe Delacourt, D. Labbe, Anne Vassault, D. Brunet‐Langot, J. Blic, P. Scheinmann (1994)
Sensitization to inhalant allergens in wheezing infants is predictive of the development of infantile asthmaAllergy, 49
J. Peat, R. Berg, W Green, C. Mellis, S Leeder, A Wolcock (1994)
Changing prevalence of asthma in Australian childrenBMJ, 308
E. Mutius, F. Martinez, C. Fritzsch, T. Nicolai, G. Roell, H. Thiemann (1994)
Prevalence of asthma and atopy in two areas of West and East Germany.American journal of respiratory and critical care medicine, 149 2 Pt 1
A. Warner, Bengt Björkstén, A. Munir, Christian Möller, C. Schou, N.-I. Kjellman (1996)
Childhood asthma and exposure to indoor allergens: lowmite levels are associated with sensitivityPediatric Allergy and Immunology, 7
M. Burr, B. Butland, S. King, E. Vaughan-Williams (1989)
Changes in asthma prevalence: two surveys 15 years apart.Archives of Disease in Childhood, 64
D. Hide, S. Matthews, S. Tariq, S. Arshad (1996)
Allergen avoidance in infancy and allergy at 4 years of ageAllergy, 51
Helsingborg) E. Young (Amersham) and the UCB ETAC® TEAM References 1
Southampton) Scientific advisory board L
N. Kjellman, S. Johansson, A. Roth (1976)
Serum IgE levels in healthy children quantified by a sandwich technique (PRIST * )Clinical & Experimental Allergy, 6
Kjellman (1993)
Is atopy prevention realisticAllergy Clin Immunol, 5
A. Oranje, J. Stalder, A. Taïeb, C. Tasset, M. Longueville (1997)
Scoring of atopic dermatitis by SCORAD using a training atlas by investigators from different disciplinesPediatric Allergy and Immunology, 8
N. Pearce, S. Weiland, U. Keil, P. Langridge, H. Anderson, D. Strachan, A. Bauman, L. Young, P. Gluyas, D. Ruffin (1993)
Self-reported prevalence of asthma symptoms in children in Australia, England, Germany and New Zealand: an international comparison using the ISAAC protocol.The European respiratory journal, 6 10
Pearce (1993)
Self-reported prevalence of asthma symptoms in children: an international comparisonEur Respir J, 6
W. Cookson, J. Faux, P. Sharp, J. Hopkin (1989)
LINKAGE BETWEEN IMMUNOGLOBULIN E RESPONSES UNDERLYING ASTHMA AND RHINITIS AND CHROMOSOME 11qThe Lancet, 333
Saarinen (1995)
Breastfeeding as prophylaxis against atopic disease: prospective follow-up study until 17 yearsLancet, 346
F. Berciano, M. Crespo, C. Bao, F. Alvarez (1987)
Serum levels of total IgE in non‐allergic childrenAllergy, 42
C. Warren, V. Holford-Strevens, C. Wong, J. Manfreda (1982)
The relationship between smoking and total immunoglobulin E levels.The Journal of allergy and clinical immunology, 69 4
B. Taylor, M. Wadsworth, J. Wadsworth, C. Peckham (1984)
CHANGES IN THE REPORTED PREVALENCE OF CHILDHOOD ECZEMA SINCE THE 1939-45 WARThe Lancet, 324
P. Holt (1994)
A potential vaccine strategy for asthma and allied atopic diseases during early childhoodThe Lancet, 344
R. Zeiger, S. Heller, M. Mellon, J. Halsey, R. Hamburger, Hugh Sampson (1992)
Genetic and environmental factors affecting the development of atopy through age 4 in children of atopic parents: a prospective randomized study of food allergen avoidancePediatric Allergy and Immunology, 3
T. Haahtela, H. Lindholm, F. Björkstén, K. Koskenvuo, L. Laitinen (1990)
Prevalence of asthma in Finnish young men.British Medical Journal, 301
C. Ulrik, V. Backer, B. Hesse, A. Dirksen (1996)
Risk factors for development of asthma in children and adolescents: findings from a longitudinal population study.Respiratory medicine, 90 10
E. Mutius, C. Fritzsch, S. Weiland, G. Roll, H. Magnussen (1992)
Prevalence of asthma and allergic disorders among children in united Germany: a descriptive comparison.British Medical Journal, 305
ETAC (Early Treatment of the Atopic Child), a multi‐centre predominantly European study to investigate the potential for cetirizine to prevent the development of asthma in infants with atopic dermatitis has completed enrolment: 817 children have been randomised to 18 months' treatment with either active or placebo and a subsequent 18 months of post‐treatment follow‐up. Results of the therapeutic effects will not be available for some time, but the study has provided an opportunity to investigate influences on sensitization to allergens in a large cohort of 1‐2 years olds with already established atopic dermatitis, resident in different countries and in different environments. The study shows that in infants with atopic dermatitis, raised serum total IgE has significantly different determinants from that a specific allergen sensitization. In infancy, increased total IgE is more affected by factors increasing risk of intercurrent infection and non‐specific airway inflammation, such as environmental tobacco smoke exposure (p < 0.001) and the use of gas cookers (p=0.02). Specific allergen sensitization as represented by detectable IgE antibodies is influenced primarily by allergen exposure. In Sweden, low level exposure to allergens is associated with reduced specific allergen sensitization rates even though the infants already have atopic dermatitis.
Pediatric Allergy and Immunology – Wiley
Published: Nov 1, 1997
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.