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Deficiency of erythrocyte glucose‐6‐phosphate dehydrogenase in Greek populations

Deficiency of erythrocyte glucose‐6‐phosphate dehydrogenase in Greek populations SUMMARY 1 Erythrocyte glucose‐6‐phosphate dehydrogenase has been measured on samples from 665 males from different parts of Greece. 2 High proportions of enzyme‐deficient subjects were found in some regions, notably the Chalkidhiki peninsula and the island of Rhodes. 3 The incidence of enzyme deficiency in different populations shows a positive correlation with the incidence of abnormal haemoglobin genes, as would be expected if all the genes are favoured by malarial selection. We are indebted to various Greek colleagues who facilitated the collection of blood or providec helpful discussion, including Prof. G. A. Deliyannis and Dr A. Ballas, Salonika, Dr Limberis and Prof. K. B. Choremis, Athens, and Dr G. Kypriotis, Rhodes. The work was supported by the Section on Geographic Medicine and Genetics, National Institute of Arthritis and Metabolic Diseases, Bethesda, Maryland. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

Deficiency of erythrocyte glucose‐6‐phosphate dehydrogenase in Greek populations

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References (21)

Publisher
Wiley
Copyright
Copyright © 1963 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1111/j.1469-1809.1963.tb01980.x
Publisher site
See Article on Publisher Site

Abstract

SUMMARY 1 Erythrocyte glucose‐6‐phosphate dehydrogenase has been measured on samples from 665 males from different parts of Greece. 2 High proportions of enzyme‐deficient subjects were found in some regions, notably the Chalkidhiki peninsula and the island of Rhodes. 3 The incidence of enzyme deficiency in different populations shows a positive correlation with the incidence of abnormal haemoglobin genes, as would be expected if all the genes are favoured by malarial selection. We are indebted to various Greek colleagues who facilitated the collection of blood or providec helpful discussion, including Prof. G. A. Deliyannis and Dr A. Ballas, Salonika, Dr Limberis and Prof. K. B. Choremis, Athens, and Dr G. Kypriotis, Rhodes. The work was supported by the Section on Geographic Medicine and Genetics, National Institute of Arthritis and Metabolic Diseases, Bethesda, Maryland.

Journal

Annals of Human Genetics – Wiley

Published: Mar 1, 1963

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