Cover Picture: Regiochemistry‐Directed Syntheses of Polyhydroxylated Alkaloids from Chiral Aziridines (Asian J. Org. Chem. 12/2015)
Cover Picture: Regiochemistry‐Directed Syntheses of Polyhydroxylated Alkaloids from Chiral...
Eum, Heesung; Choi, Jihye; Cho, Cheon‐Gyu; Ha, Hyun‐Joon
2015-12-01 00:00:00
The syntheses of two different classes of compounds branched from a common synthetic intermediate were developed by Hyun‐Joon Ha and co‐workers. Two different regiochemical pathways of aziridine ring‐opening of 2‐(dihydroxylated‐alkyl)aziridines provide easy access to two diverse classes of compounds including a variety of pyrrolidine‐ and piperidine‐based polyhydroxylated natural products and their analogues. This strategy, so called “regiochemistry‐directed branches for 2‐substituted aziridines”, is applicable for the easy preparation of structurally diverse and biologically important molecules. More information can be found in the full paper by H.‐J. Ha et al. (DOI: 10.1002/ajoc.201500285).
http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.pngAsian Journal of Organic ChemistryWileyhttp://www.deepdyve.com/lp/wiley/cover-picture-regiochemistry-directed-syntheses-of-polyhydroxylated-Cn37OnDH60
Cover Picture: Regiochemistry‐Directed Syntheses of Polyhydroxylated Alkaloids from Chiral Aziridines (Asian J. Org. Chem. 12/2015)
The syntheses of two different classes of compounds branched from a common synthetic intermediate were developed by Hyun‐Joon Ha and co‐workers. Two different regiochemical pathways of aziridine ring‐opening of 2‐(dihydroxylated‐alkyl)aziridines provide easy access to two diverse classes of compounds including a variety of pyrrolidine‐ and piperidine‐based polyhydroxylated natural products and their analogues. This strategy, so called “regiochemistry‐directed branches for 2‐substituted aziridines”, is applicable for the easy preparation of structurally diverse and biologically important molecules. More information can be found in the full paper by H.‐J. Ha et al. (DOI: 10.1002/ajoc.201500285).
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