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Coronary Intervention with the Excimer Laser: A Current Perspective

Coronary Intervention with the Excimer Laser: A Current Perspective One variety of the excimer coronary laser system (Advanced Interventional Systems) has been available for use in selected clinical centers from 1989 through 1995. This over‐the‐wire catheter‐laser system uses a 308‐nm laser and requires prepositioning of a 0.014′’to 0.018′’guidewire across the target stenosis. Development of the coronary laser system was stimulated by the limitations of conventional angioplasty, which have included abrupt reclosure, coronary dissection, restenosis, and chronic total occlusion. The excimer coronary laser angioplasty (ELCA) registry includes nearly 4,000 patients who have undergone attempted laser angioplasty. A success rate comparable to standard balloon angioplasty and an acceptably low complication rate were achieved in this registry database. While laser angioplasty has been promoted for long, diffuse lesions, total occlusions, lesions with substantial side branch involvement, and a possible therapy to reduce the incidence of restenosis, the highly selected nature of patients enrolled in the registry prevents any definite conclusions regarding the utility of intracoronary laser in these potential indications. Additionally, the advent of newer technologies, including rotablator and stenting, may further erode any potential advantages of coronary laser angioplasty. Randomized trials of newer interventional devices will be required to determine their true value and clinical utility. (J Interven Cardiol 1996;9:175–178) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Interventional Cardiology Wiley

Coronary Intervention with the Excimer Laser: A Current Perspective

REEDER, GUY S.
Journal of Interventional Cardiology , Volume 9 (2) – Apr 1, 1996
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References (15)

Publisher
Wiley
Copyright
Copyright © 1996 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0896-4327
eISSN
1540-8183
DOI
10.1111/j.1540-8183.1996.tb00612.x
Publisher site
See Article on Publisher Site

Abstract

One variety of the excimer coronary laser system (Advanced Interventional Systems) has been available for use in selected clinical centers from 1989 through 1995. This over‐the‐wire catheter‐laser system uses a 308‐nm laser and requires prepositioning of a 0.014′’to 0.018′’guidewire across the target stenosis. Development of the coronary laser system was stimulated by the limitations of conventional angioplasty, which have included abrupt reclosure, coronary dissection, restenosis, and chronic total occlusion. The excimer coronary laser angioplasty (ELCA) registry includes nearly 4,000 patients who have undergone attempted laser angioplasty. A success rate comparable to standard balloon angioplasty and an acceptably low complication rate were achieved in this registry database. While laser angioplasty has been promoted for long, diffuse lesions, total occlusions, lesions with substantial side branch involvement, and a possible therapy to reduce the incidence of restenosis, the highly selected nature of patients enrolled in the registry prevents any definite conclusions regarding the utility of intracoronary laser in these potential indications. Additionally, the advent of newer technologies, including rotablator and stenting, may further erode any potential advantages of coronary laser angioplasty. Randomized trials of newer interventional devices will be required to determine their true value and clinical utility. (J Interven Cardiol 1996;9:175–178)

Journal

Journal of Interventional Cardiology – Wiley

Published: Apr 1, 1996

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