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Confirmation of linkage between antithrombin III and Duffy blodd group and assignment of AT3 to 1q22 → q25

Confirmation of linkage between antithrombin III and Duffy blodd group and assignment of AT3 to... SUMMARY Linkage studies on two families segregating for antithrombin III deficiency confirm the linkage between AT3 and the Duffy blood group. The maximum lod score including two published families is +4.2 at recombination fractions around 0.1. Two patients with deletions of 1q have 1/2 levels of antithrombin III suggesting that the AT3 locus lies in bands 1 q22 → 1q25. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

Confirmation of linkage between antithrombin III and Duffy blodd group and assignment of AT3 to 1q22 → q25

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References (23)

Publisher
Wiley
Copyright
Copyright © 1982 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1111/j.1469-1809.1982.tb00692.x
Publisher site
See Article on Publisher Site

Abstract

SUMMARY Linkage studies on two families segregating for antithrombin III deficiency confirm the linkage between AT3 and the Duffy blood group. The maximum lod score including two published families is +4.2 at recombination fractions around 0.1. Two patients with deletions of 1q have 1/2 levels of antithrombin III suggesting that the AT3 locus lies in bands 1 q22 → 1q25.

Journal

Annals of Human GeneticsWiley

Published: Jan 1, 1982

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