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N. Kirchhof, S. Shibata, M. Wijkstrom, D. Kulick, C. Salerno, S. Clemmings, Y. Heremans, U. Galili, D. Sutherland, A. Dalmasso, B. Hering (2004)
Reversal of diabetes in non‐immunosuppressed rhesus macaques by intraportal porcine islet xenografts precedes acute cellular rejectionXenotransplantation, 11
D. Al‐Adra, R. Gill, S. Imes, D. O’Gorman, T. Kin, S.J. Axford, Xinzhe Shi, P. Senior, A. Shapiro (2014)
Single-Donor Islet Transplantation and Long-term Insulin Independence in Select Patients With Type 1 Diabetes MellitusTransplantation, 98
L. Moberg (2005)
The Role of the Innate Immunity in Islet TransplantationUpsala Journal of Medical Sciences, 110
He Xu, Xiaojie Zhang, R. Mannon, A. Kirk (2006)
Platelet-derived or soluble CD154 induces vascularized allograft rejection independent of cell-bound CD154.The Journal of clinical investigation, 116 3
P. Nesargikar, B. Spiller, R. Chavez (2012)
The complement system: history, pathways, cascade and inhibitors.European journal of microbiology & immunology, 2 2
D. Töröcsik, L. Széles, G. Paragh, Z. Rákosy, H. Bárdos, L. Nagy, M. Balázs, A. Inbal, R. Ádány (2010)
Factor XIII-A is involved in the regulation of gene expression in alternatively activated human macrophagesThrombosis and Haemostasis, 104
B. Martin, K. Samy, K. Samy, M. Lowe, P. Thompson, J. Cano, A. Farris, Mingqing Song, C. Dove, F. Leopardi, E. Strobert, J. Jenkins, B. Collins, C. Larsen, A. Kirk, A. Kirk (2015)
Dual Islet Transplantation Modeling of the Instant Blood‐Mediated Inflammatory ReactionAmerican Journal of Transplantation, 15
Patrick Hangge, J. Stone, H. Albadawi, Y. Zhang, A. Khademhosseini, R. Oklu (2017)
Hemostasis and nanotechnology.Cardiovascular diagnosis and therapy, 7 Suppl 3
M. Mezger, H. Nording, R. Sauter, T. Graf, C. Heim, N. Bubnoff, S. Ensminger, H. Langer (2019)
Platelets and Immune Responses During ThromboinflammationFrontiers in Immunology, 10
B. Ekser, David Cooper, A. Tector (2015)
The need for xenotransplantation as a source of organs and cells for clinical transplantation.International journal of surgery, 23 Pt B
M. Kanak, M. Takita, F. Kunnathodi, Michael Lawrence, M. Levy, B. Naziruddin (2014)
Inflammatory Response in Islet TransplantationInternational Journal of Endocrinology, 2014
M. Ji, S. Yi, H. Smith-Hurst, P. Phillips, Jingjing Wu, W. Hawthorne, P. O’Connell (2011)
The Importance of Tissue Factor Expression by Porcine NICC in Triggering IBMIR in the Xenograft SettingTransplantation, 91
NPIs promote FXIIIa expression, and hCD46 reduces the expression at 24 h. Immunohistochemical staining of FXIIIa in the hCD46/GTKO, GTKO islets, and MS at 1 and 24 h (A)
Andy Long, E. Kenne, R. Jung, T. Fuchs, T. Renné (2016)
Contact system revisited: an interface between inflammation, coagulation, and innate immunityJournal of Thrombosis and Haemostasis, 14
W. Bennet, C. Groth, Rolf Larsson, B. Nilsson, O. Korsgren (2000)
Isolated Human Islets Trigger an Instant Blood Mediated Inflammatory Reaction: Implications for Intraportal Islet Transplantation as a Treatment for Patients with Type 1 DiabetesUpsala Journal of Medical Sciences, 105
W. Bennet, B. Sundberg, T. Lundgren, A. Tibell, C. Groth, A. Richards, D. White, G. Elgue, R. Larsson, B. Nilsson, O. Korsgren (2000)
Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: protective effects of sCR1 and heparin.Transplantation, 69 5
N. Mor‐Vaknin, A. Punturieri, Kajal Sitwala, D. Markovitz (2003)
Vimentin is secreted by activated macrophagesNature Cell Biology, 5
Julie Williams, N. Mackman (2012)
Tissue factor in health and disease.Frontiers in bioscience, 4
S. Antoniak (2018)
The coagulation system in host defenseResearch and Practice in Thrombosis and Haemostasis, 2
M. Aringer, C. Günther, M. Lee-Kirsch (2013)
Innate immune processes in lupus erythematosus.Clinical immunology, 147 3
A. Stephan (2017)
Organ Shortage: Can We Decrease the Demand?Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 15 Suppl 1
K. Samy, B. Martin, N. Turgeon, A. Kirk (2014)
Islet cell xenotransplantation: a serious look toward the clinicXenotransplantation, 21
G. Abouna (2008)
Organ shortage crisis: problems and possible solutions.Transplantation proceedings, 40 1
B. Nilsson (2008)
The instant blood‐mediated inflammatory reaction in xenogeneic islet transplantationXenotransplantation, 15
D. Windt, M. Marigliano, Jing He, T. Votyakova, G. Echeverri, B. Ekser, D. Ayares, F. Lakkis, D. Cooper, M. Trucco, R. Bottino (2012)
Early Islet Damage after Direct Exposure of Pig Islets to Blood: Has Humoral Immunity Been Underestimated?Cell Transplantation, 21
R. Giorno (1985)
Immunohistochemical analysis of the distribution of vimentin in human peripheral lymphoid tissuesThe Anatomical Record, 211
J. Tjernberg, K. Ekdahl, John Lambris, O. Korsgren, B. Nilsson (2008)
Acute Antibody-Mediated Complement Activation Mediates Lysis of Pancreatic Islets Cells and May Cause Tissue Loss in Clinical Islet TransplantationTransplantation, 85
P. Zipfel, S. Heinen, M. Józsi, C. Skerka (2006)
Complement and diseases: defective alternative pathway control results in kidney and eye diseases.Molecular immunology, 43 1-2
M. Schmelzle, J. Esch, S. Robson (2010)
Coagulation, platelet activation and thrombosis in xenotransplantationCurrent Opinion in Organ Transplantation, 15
T. Renné, A. Schmaier, Katrin Nickel, M. Blombäck, C. Maas (2010)
In vivo roles of factor XII.Blood, 120 22
J. Sheen, P. Heeger (2015)
Effects of complement activation on allograft injuryCurrent Opinion in Organ Transplantation, 20
B. Reichart, H. Niemann, T. Chavakis, J. Denner, E. Jaeckel, B. Ludwig, Georg Marckmann, A. Schnieke, R. Schwinzer, Jochen Seissler, R. Tönjes, N. Klymiuk, E. Wolf, S. Bornstein (2014)
Xenotransplantation of Porcine Islet Cells as a Potential Option for the Treatment of Type 1 Diabetes in the FutureHormone and Metabolic Research, 47
AE Starr, CL Bellac, A Dufour, V Goebeler, CM Overall (2012)
Biochemical characterization and N‐terminomics analysis of leukolysin, the membrane‐type 6 matrix metalloprotease (MMP25): chemokine and vimentin cleavages enhance cell migration and macrophage phagocytic activities, 287
intraportal transplantation to cynomolgus monkeys : protective effects of sCR 1 and heparin
PhD Verginella, PhD Vodopivec, PhD Wakounig, Javier Domingo, Luigi Finocchietti, Vesna ć, Le e, la, Gary Cohen (1917)
Historical ReviewActa Radiologica, 3
S. Palta, R. Saroa, A. Palta (2014)
Overview of the coagulation systemIndian Journal of Anaesthesia, 58
S. Maat, C. Maas (2016)
Factor XII: form determines functionJournal of Thrombosis and Haemostasis, 14
F. Swieringa, H. Spronk, J. Heemskerk, P. Meijden (2018)
Integrating platelet and coagulation activation in fibrin clot formationResearch and Practice in Thrombosis and Haemostasis, 2
P. Thompson, I. Badell, M. Lowe, JA Cano, Mingqing Song, F. Leopardi, J. Avila, R. Ruhil, E. Strobert, G. Korbutt, G. Rayat, Rajotte Rv, N. Iwakoshi, C. Larsen, A. Kirk (2011)
Islet Xenotransplantation Using Gal‐Deficient Neonatal Donors Improves Engraftment and FunctionAmerican Journal of Transplantation, 11
CL Nikolajsen, TF Dyrlund, ET Poulsen, JJ Enghild, C Scavenius (2014)
Coagulation factor XIIIa substrates in human plasma: identification and incorporation into the clot, 289
L. Moberg, H. Johansson, A. Lukinius, C. Berne, A. Foss, R. Källen, Ø. Østraat, K. Salmela, A. Tibell, G. Tufveson, G. Elgue, K. Ekdahl, O. Korsgren, B. Nilsson (2002)
Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantationThe Lancet, 360
Marie-Emilie Francart, A. Vanwynsberghe, Justine Lambert, Morgane Bourcy, Anthony Genna, J. Ancel, Jennifer Pérez-Boza, A. Noël, P. Birembaut, I. Struman, M. Polette, C. Gilles (2020)
Vimentin prevents a miR-dependent negative regulation of tissue factor mRNA during epithelial–mesenchymal transitions and facilitates early metastasisOncogene, 39
B. Bastani (2019)
The present and future of transplant organ shortage: some potential remediesJournal of Nephrology, 33
D. Saha, S. S, E. Sergeeva, Z. Ionova, A. Gorbach (2015)
Tissue factor and atherothrombosis.Current pharmaceutical design, 21 9
K. Samy, Q. Gao, R. Davis, Mingqing Song, Z. Fitch, M. Mulvihill, A. MacDonald, F. Leopardi, T. How, K. Williams, G. Devi, B. Collins, Xunrong Luo, A. Kirk (2019)
The role of human CD46 in early xenoislet engraftment in a dual transplant modelXenotransplantation, 26
I. Kourtzelis, P. Magnusson, Klára Kotlabová, John Lambris, T. Chavakis (2015)
Regulation of Instant Blood Mediated Inflammatory Reaction (IBMIR) in Pancreatic Islet Xeno-Transplantation: Points for Therapeutic Interventions.Advances in experimental medicine and biology, 865
C. Nikolajsen, Thomas Dyrlund, E. Poulsen, J. Enghild, C. Scavenius (2014)
Coagulation Factor XIIIa Substrates in Human PlasmaThe Journal of Biological Chemistry, 289
K. Samy, R. Davis, Q. Gao, B. Martin, M. Song, J. Cano, A. Farris, A. McDonald, E. Gall, C. Dove, F. Leopardi, T. How, K. Williams, G. Devi, B. Collins, A. Kirk (2018)
Early barriers to neonatal porcine islet engraftment in a dual transplant modelAmerican Journal of Transplantation, 18
S. Butenas, T. Orfeo, K. Mann (2009)
Tissue factor in coagulation: Which? Where? When?Arteriosclerosis, thrombosis, and vascular biology, 29 12
J. Heemskerk, N. Mattheij, J. Cosemans (2013)
Platelet‐based coagulation: different populations, different functionsJournal of Thrombosis and Haemostasis, 11
Stephanie Smith, R. Travers, J. Morrissey (2015)
How it all starts: Initiation of the clotting cascadeCritical Reviews in Biochemistry and Molecular Biology, 50
O. Eriksson, Camilla Mohlin, B. Nilsson, K. Ekdahl (2019)
The Human Platelet as an Innate Immune Cell: Interactions Between Activated Platelets and the Complement SystemFrontiers in Immunology, 10
D. Cooper, M. Ezzelarab, H. Hara, H. Iwase, Whayoung Lee, M. Wijkstrom, R. Bottino (2016)
The pathobiology of pig‐to‐primate xenotransplantation: a historical reviewXenotransplantation, 23
D. Windt, D. Windt, R. Bottino, Anna Casu, N. Campanile, C. Smetanka, Jing He, N. Murase, H. Hara, S. Ball, B. Loveland, D. Ayares, F. Lakkis, D. Cooper, M. Trucco (2009)
Long‐Term Controlled Normoglycemia in Diabetic Non‐Human Primates After Transplantation with hCD46 Transgenic Porcine IsletsAmerican Journal of Transplantation, 9
Joanne Mitchell, Nicola Mutch (2019)
Let's cross‐link: diverse functions of the promiscuous cellular transglutaminase factor XIII‐AJournal of Thrombosis and Haemostasis, 17
P. Thompson, K. Cardona, M. Russell, I. Badell, V. Shaffer, G. Korbutt, G. Rayat, J. Cano, Mingqing Song, W. Jiang, E. Strobert, Rajotte Rv, T. Pearson, Allan Kirk, C. Larsen (2011)
CD40‐Specific Costimulation Blockade Enhances Neonatal Porcine Islet Survival in Nonhuman PrimatesAmerican Journal of Transplantation, 11
E. Cozzi, D. White (1995)
The generation of transgenic pigs as potential organ donors for humansNature Medicine, 1
S. Linthout, K. Miteva, C. Tschöpe (2014)
Crosstalk between fibroblasts and inflammatory cells.Cardiovascular research, 102 2
Author manuscript; available in PMC
L. Burzynski, M. Humphry, Katerina Pyrillou, Kimberley Wiggins, Julie Chan, N. Figg, Lauren Kitt, C. Summers, K. Tatham, Paul Martin, M. Bennett, Murray Clarke (2019)
The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by ThrombinImmunity, 50
(2015)
Total Pancreatectomy With Islet Cell Transplantation for the Treatment of Pancreatic Cancer.Clinical journal of oncology nursing, 19 4
P. Thompson, I. Badell, M. Lowe, AP Turner, J. Cano, J. Avila, A. Azimzadeh, Xiangfei Cheng, R. Pierson, Brandi Johnson, Jan Robertson, Mingqing Song, F. Leopardi, E. Strobert, G. Korbutt, G. Rayat, Rajotte Rv, C. Larsen, A. Kirk (2012)
Alternative Immunomodulatory Strategies for Xenotransplantation: CD40/154 Pathway‐Sparing Regimens Promote Xenograft SurvivalAmerican Journal of Transplantation, 12
R. Scharf (2018)
Platelet Signaling in Primary Haemostasis and Arterial Thrombus Formation: Part 1Hämostaseologie, 38
R. Palma, P. Cirillo, G. Ciccarelli, G. Barra, Stefano Conte, Grazia Pellegrino, G. Pasquale, G. Nassa, F. Pacifico, A. Leonardi, L. Insabato, G. Calì, P. Golino, G. Cimmino (2016)
Expression of functional tissue factor in activated T-lymphocytes in vitro and in vivo: A possible contribution of immunity to thrombosis?International journal of cardiology, 218
Aman Opneja, Sargam Kapoor, Evi Stavrou (2019)
Contribution of platelets, the coagulation and fibrinolytic systems to cutaneous wound healing.Thrombosis research, 179
M. Goto, J. Tjernberg, D. Dufrane, G. Elgue, D. Brandhorst, K. Ekdahl, H. Brandhorst, L. Wennberg, Y. Kurokawa, S. Satomi, John Lambris, P. Gianello, O. Korsgren, B. Nilsson (2008)
Dissecting the instant blood‐mediated inflammatory reaction in islet xenotransplantationXenotransplantation, 15
S. Mandal, U. Pendurthi, L. Rao (2007)
Tissue factor trafficking in fibroblasts: involvement of protease-activated receptor-mediated cell signaling.Blood, 110 1
M. Mohiuddin, Avneesh Singh, P. Corcoran, R. Hoyt, Marvin Thomas, D. Ayares, K. Horvath (2014)
Genetically engineered pigs and target-specific immunomodulation provide significant graft survival and hope for clinical cardiac xenotransplantation.The Journal of thoracic and cardiovascular surgery, 148 3
D. Adams, A. Kadner, Raymond Chen, R. Farivar, J. Logan, L. Diamond (2001)
Human membrane cofactor protein (MCP, CD 46) protects transgenic pig hearts from hyperacute rejection in primatesXenotransplantation, 8
Xenotransplantation – Wiley
Published: May 1, 2021
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