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Cloning, expression, purification, crystallization and preliminary X‐ray crystallographic analysis of interleukin‐4‐inducing principle from Schistosoma mansoni eggs (IPSE/alpha‐1)

Cloning, expression, purification, crystallization and preliminary X‐ray crystallographic... The interleukin‐4‐inducing principle from Schistosoma mansoni eggs (IPSE/alpha‐1) triggers the release of large amounts of interleukin‐4 from human blood basophils, thus presumably playing an immunomodulatory role during schistosome infection. IPSE/alpha‐1 was crystallized and a native X‐ray data set was collected to 1.66 Å resolution from a single crystal at 100 K using synchrotron radiation. The crystal belonged to space group P61 or P65, with one molecule per asymmetric unit. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Crystallographica Section F Wiley

Cloning, expression, purification, crystallization and preliminary X‐ray crystallographic analysis of interleukin‐4‐inducing principle from Schistosoma mansoni eggs (IPSE/alpha‐1)

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References (6)

Publisher
Wiley
Copyright
International Union of Crystallography, 2009
ISSN
1744-3091
eISSN
1744-3091
DOI
10.1107/S1744309109015899
pmid
19478439
Publisher site
See Article on Publisher Site

Abstract

The interleukin‐4‐inducing principle from Schistosoma mansoni eggs (IPSE/alpha‐1) triggers the release of large amounts of interleukin‐4 from human blood basophils, thus presumably playing an immunomodulatory role during schistosome infection. IPSE/alpha‐1 was crystallized and a native X‐ray data set was collected to 1.66 Å resolution from a single crystal at 100 K using synchrotron radiation. The crystal belonged to space group P61 or P65, with one molecule per asymmetric unit.

Journal

Acta Crystallographica Section FWiley

Published: Jun 1, 2009

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