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Clinical Research Office of the Endourological Society Global GreenLight Laser Study: Outcomes from a contemporary series of 713 patients

Clinical Research Office of the Endourological Society Global GreenLight Laser Study: Outcomes... Objective To evaluate the outcome in patients undergoing photoselective vaporization of the prostate for benign prostatic obstruction as part of the Clinical Research Office of the Endourological Society Global GreenLight Laser Study. Methods Data were collected on 713 patients with lower urinary tract symptoms suggestive of benign prostatic obstruction undergoing photoselective vaporization of the prostate at 25 centers worldwide, between April 2010 and April 2012. Three types of GreenLight laser powers were used: 80 W, 120 W or 180 W. Intraoperative and postoperative complications were recorded. Outcome parameters measured at baseline, 6–12 weeks, 6 months and 12 months were: uroflow measurements, International Prostate Symptom Score; prostate‐specific antigen and International Index of Erectile Function. Results Operating time was shortest with the 180‐W laser at 53.8 min. Intraoperatively, bleeding occurred in 3.1% of patients. Statistically significant changes were reported in maximum flow rate, postvoid residual urine, International Prostate Symptom Score, quality of life score and prostate‐specific antigen (P < 0.01) at each time‐point assessed for the 80‐ and 120‐W lasers as well as for the 180‐W laser, with the exception of prostate‐specific antigen at 6 months and 12 months. There were 14 Clavien–Dindo grade III‐A complications and two grade III‐B. The incontinence rate at 12 months was 6.3%, 4.5%, and 2.6% for the 80, 120 and 180 W lasers, respectively. The overall blood transfusion rate was 0.4%. Conclusions Objective and subjective improvement after GreenLight laser treatment worldwide was significant at 1‐year follow up. Morbidity and complications were low. Although not a randomized control study, the data can provide an indication of the outcome of the different GreenLight laser powers. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Journal of Urology Wiley

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References (29)

Publisher
Wiley
Copyright
Copyright © 2015 The Japanese Urological Association
ISSN
0919-8172
eISSN
1442-2042
DOI
10.1111/iju.12906
pmid
26307430
Publisher site
See Article on Publisher Site

Abstract

Objective To evaluate the outcome in patients undergoing photoselective vaporization of the prostate for benign prostatic obstruction as part of the Clinical Research Office of the Endourological Society Global GreenLight Laser Study. Methods Data were collected on 713 patients with lower urinary tract symptoms suggestive of benign prostatic obstruction undergoing photoselective vaporization of the prostate at 25 centers worldwide, between April 2010 and April 2012. Three types of GreenLight laser powers were used: 80 W, 120 W or 180 W. Intraoperative and postoperative complications were recorded. Outcome parameters measured at baseline, 6–12 weeks, 6 months and 12 months were: uroflow measurements, International Prostate Symptom Score; prostate‐specific antigen and International Index of Erectile Function. Results Operating time was shortest with the 180‐W laser at 53.8 min. Intraoperatively, bleeding occurred in 3.1% of patients. Statistically significant changes were reported in maximum flow rate, postvoid residual urine, International Prostate Symptom Score, quality of life score and prostate‐specific antigen (P < 0.01) at each time‐point assessed for the 80‐ and 120‐W lasers as well as for the 180‐W laser, with the exception of prostate‐specific antigen at 6 months and 12 months. There were 14 Clavien–Dindo grade III‐A complications and two grade III‐B. The incontinence rate at 12 months was 6.3%, 4.5%, and 2.6% for the 80, 120 and 180 W lasers, respectively. The overall blood transfusion rate was 0.4%. Conclusions Objective and subjective improvement after GreenLight laser treatment worldwide was significant at 1‐year follow up. Morbidity and complications were low. Although not a randomized control study, the data can provide an indication of the outcome of the different GreenLight laser powers.

Journal

International Journal of UrologyWiley

Published: Dec 1, 2015

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