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CEPH Genotype Database Version 10 Released

CEPH Genotype Database Version 10 Released doi: 10.1046/j.1529-8817.2005.00187.x ANNOUNCEMENT The Foundation Jean Dausset – CEPH has re- pairs of syntenic marker loci, on each pair of segregat- leased Version 10 of the CEPH Genotype Database ing chromosomes. Each of 32,023 markers was assigned (www.cephb.fr/cephdb). The database contains DNA to a chromosome by linkage or by other means. The marker genotypes that have accumulated on 874 indi- CEPH database web site supports downloading geno- viduals of the 65 CEPH Reference Familes (Genomics types for the reference familes by marker ID, chromo- 6:575-577, 1990) since 1985. The present version of some, family(ies) and observed heterozygote frequency the database contains genotypes for 32,356 polymor- via the new version of the CEPH database browser. phic markers. These include data for a total of 21,480 In addition to genotypes by family, downloaded infor- bi-allelic markers, of which 17,512 may be identified mation includes marker allele frequencies, lists of close in dbSNP by rs or ss numbers. A subset of the geno- (linked) markers and graphically represented pedigrees types for 2771 of these SNPs was used to construct the with genotypes. V10 provides a link to the NCBI En- CEPH family-based SNP linkage map of the human trez home page, allowing entry into the current build genome by Matisse et al. (Am J Hum Genetics 73:271- of dbSNP, UniSTS and other NCBI databases. 284, 2003). V10 also contains genotypes for more than CEPH collaborators and others who have genotyped 9,900 microsatellite markers. The mean observed het- CEPH reference families can submit marker data di- erozygote frequency of all the loci in V10.0 is 0.438, and rectly to V10 by interacting with the CEPH WEB for identifiable microsatellite loci 0.698, of which 56% server (www.cephb.fr/cephdb). Marker submissions re- are highly polymorphic (obs. het. ≥ 0.70). The CEPH quire a submitter password, available on request to database now manages 6,081,570 genotypes. A total of cephdbm@cephb.fr. File submission is also available af- 25,924,717 lod scores has been computed between all ter consultation with CEPH. University College London 2005 Annals of Human Genetics (2005) 69,347 347 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

CEPH Genotype Database Version 10 Released

Annals of Human Genetics , Volume 69 (3) – May 1, 2005
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Publisher
Wiley
Copyright
Copyright © 2005 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1046/J.1469-1809.2005.00187.x
Publisher site
See Article on Publisher Site

Abstract

doi: 10.1046/j.1529-8817.2005.00187.x ANNOUNCEMENT The Foundation Jean Dausset – CEPH has re- pairs of syntenic marker loci, on each pair of segregat- leased Version 10 of the CEPH Genotype Database ing chromosomes. Each of 32,023 markers was assigned (www.cephb.fr/cephdb). The database contains DNA to a chromosome by linkage or by other means. The marker genotypes that have accumulated on 874 indi- CEPH database web site supports downloading geno- viduals of the 65 CEPH Reference Familes (Genomics types for the reference familes by marker ID, chromo- 6:575-577, 1990) since 1985. The present version of some, family(ies) and observed heterozygote frequency the database contains genotypes for 32,356 polymor- via the new version of the CEPH database browser. phic markers. These include data for a total of 21,480 In addition to genotypes by family, downloaded infor- bi-allelic markers, of which 17,512 may be identified mation includes marker allele frequencies, lists of close in dbSNP by rs or ss numbers. A subset of the geno- (linked) markers and graphically represented pedigrees types for 2771 of these SNPs was used to construct the with genotypes. V10 provides a link to the NCBI En- CEPH family-based SNP linkage map of the human trez home page, allowing entry into the current build genome by Matisse et al. (Am J Hum Genetics 73:271- of dbSNP, UniSTS and other NCBI databases. 284, 2003). V10 also contains genotypes for more than CEPH collaborators and others who have genotyped 9,900 microsatellite markers. The mean observed het- CEPH reference families can submit marker data di- erozygote frequency of all the loci in V10.0 is 0.438, and rectly to V10 by interacting with the CEPH WEB for identifiable microsatellite loci 0.698, of which 56% server (www.cephb.fr/cephdb). Marker submissions re- are highly polymorphic (obs. het. ≥ 0.70). The CEPH quire a submitter password, available on request to database now manages 6,081,570 genotypes. A total of cephdbm@cephb.fr. File submission is also available af- 25,924,717 lod scores has been computed between all ter consultation with CEPH. University College London 2005 Annals of Human Genetics (2005) 69,347 347

Journal

Annals of Human Genetics – Wiley

Published: May 1, 2005

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