Access the full text.
Sign up today, get DeepDyve free for 14 days.
Aurias Aurias, Prieur Prieur, Dutrillaux Dutrillaux, Lejeune Lejeune (1978)
Systematic analysis of 95 reciprocal translocations of autosomesHum. Genet., 45
A. Boué, P. Gallano (1984)
A collaborative study of the segregation of inherited chromosome structural rearrangements in 1356 prenatal diagnosesPrenatal Diagnosis, 4
R. Berger, C. Bloomfield, G. Sutherland (1985)
Report of the Committee on Chromosome Rearrangements in Neoplasia and on Fragile Sites.Cytogenetics and cell genetics, 40 1-4
F. Hecht, B. Hecht (1984)
Fragile sites and chromosome breakpoints in constitutional rearrangements I. AmniocentesisClinical Genetics, 26
G. Holmquist, M. Gray, T. Porter, John Jordan (1982)
Characterization of Giemsa dark- and light-band DNACell, 31
C. Yu, D. Borgaonkar, D. Bolling (1978)
Break points in human chromosomes.Human heredity, 28 3
(1977)
Localization of chromatid T ~ T R I L L A U X , B . . IYImERis
(1984)
Excess of mental retardation
(1981)
The erolut , ion o f t h e New York State Chromosome R , egiAtry
Braekeleer Braekeleer, Smith Smith, Lin Lin (1985)
Fragile sites and structural rearrangements in cancerHum. Genet., 69
By Hook, P. Cross (1987)
Rates of mutant and inherited structural cytogenetic abnormalities detected at amniocentesis: results on about 63000 fetusesAnnals of Human Genetics, 51
Dutrillaux Dutrillaux, Couturier Couturier, Viegas‐Pequignot Viegas‐Pequignot, Schaison Schaison (1977)
Localization of chromatid breaks in Fanconi's anemia using three consecutive stainsHum. Genet., 37
Mattei Mattei, Sociah Sociah, Mattel Mattel (1984)
Chromosome 15 anomalies and the Prader‐Willi syndrome: cytogenetic analysisHum. Genet., 66
21-51, in couples u-ith recurrent fetal wastage. H,um. Genet. 65. 336-354. or congenital rnalformat.ion in reciproral translocation in man
(1980)
Sonrantlom distribution of exchange points in patients with reciprocal translocat , ions
Smith Smith, Manuel Manuel, Den Dulk Den Dulk, Lawrence Lawrence (1985)
A male with two different familial autosomal fragile sites and a eytogenetically abnormal offspringAnn. Génét., 28
M. Mattei, S. Aymé, J. Mattéi, Y. Aurran, F. Giraud (1979)
Distribution of spontaneous chromosome breaks in man.Cytogenetics and cell genetics, 23 1-2
(1980)
La localisation exacte de certains sites fragiles reste a
Dutrillaux Dutrillaux, Muleris Muleris, Prieur Prieur (1985)
La localisation exacte de certains sites fragiles reste à préeiser. Exernple du fra(10) sensible au folateAnn. Genet., 28
(1982)
Complex chromosomal rearrangements ( CCR ) and tlieir geiirtic * c w uences
-syntlrome : an unusual case and diagnosis by in situ hybridization with chromosome 18-specific alphoid DXA stquence
Hecht Hecht (1986)
Rare. polymorphic, and common fragile sites: a classificationHum. Genet., 74
Fryns Fryns, Kleczkowska Kleczkowska, Kubien Kubien, Petit Petit, Berghe Berghe (1984)
Cytogenetic survey in couples with recurrent fetal wastageHum. Genet., 65
(2020)
International System for Human Cytogenetic NomenclatureDefinitions
P. Jacobs, K. Buckton, C. Cunningham, M. Newton (1974)
An Analysis of the Break Points of Structural Rearrangements in ManJournal of Medical Genetics, 11
A. Smith, A. Manuel, G. Dulk, R. Lawrence (1985)
A male with two different familial autosomal fragile sites and a cytogenetically abnormal offspring.Annales de genetique, 28 4
J. Davis, B. Rogers, R. Hagaman, Cole Thies, I. Veomett (1985)
Balanced reciprocal translocations: risk factors for aneuploid segregant viabilityClinical Genetics, 27
Hubert Hubert, Bourgeois Bourgeois (1986)
The nuclear skeleton and the spatial arrangement of chromosomes in the interphase nucleus of vertebrate somatic cellsHum. Genet., 74
F. Hecht, B. Hecht (1984)
Fragile sites and chromosome breakpoints in constitutional rearrangements II. Spontaneous abortions, stillbirths and newbornsClinical Genetics, 26
J. Haldane, C. Smith (1948)
A simple exact test for birth-order effect.Annals of eugenics, 14 2
Fryns Fryns, Kleczkowska Kleczkowska, Kubien Kubien, Berghe Berghe (1986)
Excess of mental retardation and/or congenital malformation in reciprocal transloea‐tion in manHum. Genet., 72
D. Borgaonkar, D. Bolling, C. Partridge, F. Ruddle, V. McKusick (1975)
Chromosomal variation in man: catalog of chromosomal variants and anomalies.Cytogenetics and cell genetics, 14 3-6
Kleczkowska Kleczkowska, Fryns Fryns, Berghe Berghe (1982)
Complex chromosomal rearrangements (CCR) and their genetic consequencesJ. Génét. Hum., 30
D. Comings (1978)
Mechanisms of chromosome banding and implications for chromosome structure.Annual review of genetics, 12
M. Braekeleer (1985)
Fragile sites and chromosome breakpoints in constitutional rearrangementsClinical Genetics, 27
Berger Berger, Bloomfield Bloomfield, Sutherland Sutherland (1985)
Report of the committee on chromosome rearrangements in neoplasia and on fragile sites. Human Gene Mapping 8, Helsinki ConferenceCytogenet. Cell Genet., 40
Fraccaro Fraccaro, Lindsten Lindsten, Ford Ford, Iselius Iselius (1980)
The 11q; 22q translocation: a European collaborative analysis of 43 casesHum. Genet., 56
Summary In an attempt to investigate possible relationships between fragile site bands and chromosome abnormalities, we have analysed the distribution of 6391 breakpoints found in constitutional rearrangements. Were relative band lengths to be ignored, a general trend for breaks to be located in fragile site bands would be confirmed. On the other hand, no difference was detected between bands with or without fragile sites if the probability of breakage for each single band is assumed to be proportional to its length. Nevertheless, a number of bands with a great excess of breakage events were identified.
Annals of Human Genetics – Wiley
Published: Oct 1, 1987
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.