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Roderick Yao, Oyediran Akinrinade, M. Chaix, S. Mital (2019)
Quality of whole genome sequencing from blood versus saliva derived DNA in cardiac patientsBMC Medical Genomics, 13
(2018)
Various R Programming Tools for Model Fitting
( Johnson SC , Koscik RL , Jonaitis EM , et al. The Wisconsin Registry for Alzheimer's prevention: a review of findings and current directions. Alzheimers Dement (Amst). 2018;10:130‐142.29322089)
Johnson SC , Koscik RL , Jonaitis EM , et al. The Wisconsin Registry for Alzheimer's prevention: a review of findings and current directions. Alzheimers Dement (Amst). 2018;10:130‐142.29322089Johnson SC , Koscik RL , Jonaitis EM , et al. The Wisconsin Registry for Alzheimer's prevention: a review of findings and current directions. Alzheimers Dement (Amst). 2018;10:130‐142.29322089, Johnson SC , Koscik RL , Jonaitis EM , et al. The Wisconsin Registry for Alzheimer's prevention: a review of findings and current directions. Alzheimers Dement (Amst). 2018;10:130‐142.29322089
( Bondi MW , Salmon DP , Galasko D , Thomas RG , Thal LJ . Neuropsychological function and apolipoprotein E genotype in the preclinical detection of Alzheimer's disease. Psychol Aging. 1999;14(2):295‐303.10403716)
Bondi MW , Salmon DP , Galasko D , Thomas RG , Thal LJ . Neuropsychological function and apolipoprotein E genotype in the preclinical detection of Alzheimer's disease. Psychol Aging. 1999;14(2):295‐303.10403716Bondi MW , Salmon DP , Galasko D , Thomas RG , Thal LJ . Neuropsychological function and apolipoprotein E genotype in the preclinical detection of Alzheimer's disease. Psychol Aging. 1999;14(2):295‐303.10403716, Bondi MW , Salmon DP , Galasko D , Thomas RG , Thal LJ . Neuropsychological function and apolipoprotein E genotype in the preclinical detection of Alzheimer's disease. Psychol Aging. 1999;14(2):295‐303.10403716
J. Langbaum, J. Karlawish, J. Roberts, E. Wood, A. Bradbury, N. High, T. Walsh, D. Gordon, Raj Aggarwal, Patricia Davis, C. Stowell, Lane Trisko, C. Langlois, E. Reiman, P. Tariot (2019)
GeneMatch: A novel recruitment registry using at-home APOE genotyping to enhance referrals to Alzheimer's prevention studiesAlzheimer's & Dementia, 15
J. Cromer, B. Harel, Karen Yu, Jaclyn Valadka, Jack Brunwin, Cameron Crawford, L. Mayes, P. Maruff (2015)
Comparison of Cognitive Performance on the Cogstate Brief Battery When Taken In-Clinic, In-Group, and UnsupervisedThe Clinical Neuropsychologist, 29
E. Reiman, Joseph Arboleda-Velasquez, Y. Quiroz, M. Huentelman, T. Beach, R. Caselli, Yinghua Chen, Yi Su, A. Myers, J. Hardy, Jean Vonsattel, S. Younkin, D. Bennett, P. Jager, E. Larson, P. Crane, C. Keene, M. Kamboh, J. Kofler, Linda Duque, J. Gilbert, H. Gwirtsman, J. Buxbaum, D. Dickson, M. Frosch, B. Ghetti, K. Lunetta, Li-San Wang, B. Hyman, W. Kukull, T. Foroud, J. Haines, R. Mayeux, M. Pericak-Vance, J. Schneider, J. Trojanowski, L. Farrer, G. Schellenberg, G. Beecham, T. Montine, G. Jun, Erin Asthana, E. Abner, P. Adams, M. Albert, R. Albin, L. Apostolova, S. Arnold, S. Asthana, C. Atwood, C. Baldwin, R. Barber, L. Barnes, S. Barral, J. Becker, D. Beekly, E. Bigio, T. Bird, D. Blacker, B. Boeve, J. Bowen, A. Boxer, J. Burke, J. Burns, N. Cairns, L. Cantwell, C. Cao, C. Carlson, C. Carlsson, R. Carney, M. Carrasquillo, H. Chui, D. Cribbs, E. Crocco, C. Cruchaga, C. DeCarli, M. Dick, R. Doody, R. Duara, N. Ertekin-Taner, Denis Evans, K. Faber, T. Fairchild, K. Fallon, D. Fardo, M. Farlow, S. Ferris, D. Galasko, M. Gearing, D. Geschwind, Valentina Ghisays, A. Goate, N. Graff-Radford, R. Green, J. Growdon, H. Hakonarson, R. Hamilton, K. Hamilton-Nelson, L. Harrell, L. Honig, R. Huebinger, C. Hulette, G. Jarvik, Lee‐way Jin, A. Karydas, M. Katz, J. Kauwe, J. Kaye, Ronald Kim, N. Kowall, J. Kramer, B. Kunkle, Amanda Kuzma, F. LaFerla, J. Lah, Y. Leung, J. Leverenz, A. Levey, Ge Li, A. Lieberman, R. Lipton, O. Lopez, C. Lyketsos, J. Malamon, D. Marson, E. Martin, F. Martiniuk, D. Mash, E. Masliah, W. McCormick, S. McCurry, A. McDavid, S. McDonough, A. Mckee, M. Mesulam, B. Miller, C. Miller, Joshua Miller, J. Morris, S. Mukherjee, A. Naj, S. O'Bryant, J. Olichney, J. Parisi, Hank Paulson, E. Peskind, Ronald Petersen, A. Pierce, W. Poon, H. Potter, L. Qu, J. Quinn, A. Raj, M. Raskind, B. Reisberg, J. Reisch, C. Reitz, J. Ringman, E. Roberson, E. Rogaeva, H. Rosen, R. Rosenberg, D. Royall, M. Sager, M. Sano, A. Saykin, L. Schneider, W. Seeley, Amanda Smith, J. Sonnen, S. Spina, P. George-Hyslop, R. Stern, R. Swerdlow, R. Tanzi, J. Troncoso, D. Tsuang, O. Valladares, V. Deerlin, L. Eldik, B. Vardarajan, H. Vinters, S. Weintraub, K. Welsh-Bohmer, K. Wilhelmsen, J. Williamson, T. Wingo, R. Woltjer, Clinton Wright, Chuang‐Kuo Wu, Chang-En Yu, Lei Yu, Yi Zhao (2020)
Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological studyNature Communications, 11
( Singh PP , Singh M , Mastana SS . APOE distribution in world populations with new data from India and the UK. Ann Hum Biol. 2006;33(3):279‐308.17092867)
Singh PP , Singh M , Mastana SS . APOE distribution in world populations with new data from India and the UK. Ann Hum Biol. 2006;33(3):279‐308.17092867Singh PP , Singh M , Mastana SS . APOE distribution in world populations with new data from India and the UK. Ann Hum Biol. 2006;33(3):279‐308.17092867, Singh PP , Singh M , Mastana SS . APOE distribution in world populations with new data from India and the UK. Ann Hum Biol. 2006;33(3):279‐308.17092867
N. Eriksson, J. Macpherson, J. Tung, Lawrence Hon, Brian Naughton, Serge Saxonov, Linda Avey, A. Wojcicki, I. Pe’er, J. Mountain, Gregory Barsh, Michael Eisen (2010)
Web-Based, Participant-Driven Studies Yield Novel Genetic Associations for Common TraitsPLoS Genetics, 6
( Caselli RJ , Langbaum J , Marchant GE , et al., Public perceptions of presymptomatic testing for Alzheimer disease. Mayo Clin Proc. 2014;89(10):1389‐1396.25171823)
Caselli RJ , Langbaum J , Marchant GE , et al., Public perceptions of presymptomatic testing for Alzheimer disease. Mayo Clin Proc. 2014;89(10):1389‐1396.25171823Caselli RJ , Langbaum J , Marchant GE , et al., Public perceptions of presymptomatic testing for Alzheimer disease. Mayo Clin Proc. 2014;89(10):1389‐1396.25171823, Caselli RJ , Langbaum J , Marchant GE , et al., Public perceptions of presymptomatic testing for Alzheimer disease. Mayo Clin Proc. 2014;89(10):1389‐1396.25171823
Lim YY (2015)
10.1016/j.neurobiolaging.2014.12.008Neurobiol Aging, 36
( Hendrie HC , Hall KS , Hui S , et al. Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans. Ann Neurol. 1995;37(1):118‐120.7818244)
Hendrie HC , Hall KS , Hui S , et al. Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans. Ann Neurol. 1995;37(1):118‐120.7818244Hendrie HC , Hall KS , Hui S , et al. Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans. Ann Neurol. 1995;37(1):118‐120.7818244, Hendrie HC , Hall KS , Hui S , et al. Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans. Ann Neurol. 1995;37(1):118‐120.7818244
S. Bardach, G. Jicha, S. Karanth, Xuan Zhang, E. Abner (2019)
Genetic Sample Provision Among National Alzheimer's Coordinating Center Participants.Journal of Alzheimer's disease : JAD, 69 1
J. Grill, D. Hoang, D. Gillen, Chelsea Cox, Adrijana Gombosev, Kirsten Klein, Steve O'Leary, M. Witbracht, A. Pierce (2018)
Constructing a Local Potential Participant Registry to Improve Alzheimer's Disease Clinical Research Recruitment.Journal of Alzheimer's disease : JAD, 63 3
( Han E , Carbonetto P , Curtis RE , et al. Clustering of 770,000 genomes reveals post‐colonial population structure of North America. Nat Commun. 2017;8(1):14238.28169989)
Han E , Carbonetto P , Curtis RE , et al. Clustering of 770,000 genomes reveals post‐colonial population structure of North America. Nat Commun. 2017;8(1):14238.28169989Han E , Carbonetto P , Curtis RE , et al. Clustering of 770,000 genomes reveals post‐colonial population structure of North America. Nat Commun. 2017;8(1):14238.28169989, Han E , Carbonetto P , Curtis RE , et al. Clustering of 770,000 genomes reveals post‐colonial population structure of North America. Nat Commun. 2017;8(1):14238.28169989
( Lim YY , Villemagne VL , Pietrzak RH , et al. APOE epsilon4 moderates amyloid‐related memory decline in preclinical Alzheimer's disease. Neurobiol Aging. 2015;36(3):1239‐1244.25559335)
Lim YY , Villemagne VL , Pietrzak RH , et al. APOE epsilon4 moderates amyloid‐related memory decline in preclinical Alzheimer's disease. Neurobiol Aging. 2015;36(3):1239‐1244.25559335Lim YY , Villemagne VL , Pietrzak RH , et al. APOE epsilon4 moderates amyloid‐related memory decline in preclinical Alzheimer's disease. Neurobiol Aging. 2015;36(3):1239‐1244.25559335, Lim YY , Villemagne VL , Pietrzak RH , et al. APOE epsilon4 moderates amyloid‐related memory decline in preclinical Alzheimer's disease. Neurobiol Aging. 2015;36(3):1239‐1244.25559335
Puneetpal Singh, Monica Singh, S. Mastana (2006)
APOE distribution in world populations with new data from India and the UKAnnals of Human Biology, 33
( Zhong K , and Cummings J . Healthybrains.org: from registry to randomization. J Prev Alzheimers Dis. 2016;3(3):123‐126.29205249)
Zhong K , and Cummings J . Healthybrains.org: from registry to randomization. J Prev Alzheimers Dis. 2016;3(3):123‐126.29205249Zhong K , and Cummings J . Healthybrains.org: from registry to randomization. J Prev Alzheimers Dis. 2016;3(3):123‐126.29205249, Zhong K , and Cummings J . Healthybrains.org: from registry to randomization. J Prev Alzheimers Dis. 2016;3(3):123‐126.29205249
( O'donoghue MC , Murphy SE , Zamboni G , Nobre AC , Mackay CE . APOE genotype and cognition in healthy individuals at risk of Alzheimer's disease: a review. Cortex. 2018;104:103‐123.29800787)
O'donoghue MC , Murphy SE , Zamboni G , Nobre AC , Mackay CE . APOE genotype and cognition in healthy individuals at risk of Alzheimer's disease: a review. Cortex. 2018;104:103‐123.29800787O'donoghue MC , Murphy SE , Zamboni G , Nobre AC , Mackay CE . APOE genotype and cognition in healthy individuals at risk of Alzheimer's disease: a review. Cortex. 2018;104:103‐123.29800787, O'donoghue MC , Murphy SE , Zamboni G , Nobre AC , Mackay CE . APOE genotype and cognition in healthy individuals at risk of Alzheimer's disease: a review. Cortex. 2018;104:103‐123.29800787
D. Blazer, G. Fillenbaum, B. Burchett (2001)
The APOE-E4 allele and the risk of functional decline in a community sample of African American and white older adults.The journals of gerontology. Series A, Biological sciences and medical sciences, 56 12
(2018)
APOE epsilon2epsilon4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults.Neurology
J. Gooblar, C. Roe, Natalie Selsor, M. Gabel, J. Morris (2015)
Attitudes of Research Participants and the General Public Regarding Disclosure of Alzheimer Disease Research Results.JAMA neurology, 72 12
M. Bondi, David Salmon, Douglas Galasko, Ronald Thomas, L. Thal (1999)
Neuropsychological function and apolipoprotein E genotype in the preclinical detection of Alzheimer's disease.Psychology and aging, 14 2
( Blazer DG , Fillenbaum G , Burchett B . The APOE‐E4 allele and the risk of functional decline in a community sample of African American and white older adults. J Gerontol A Biol Sci Med Sci. 2001;56(12):M785‐M789.11723155)
Blazer DG , Fillenbaum G , Burchett B . The APOE‐E4 allele and the risk of functional decline in a community sample of African American and white older adults. J Gerontol A Biol Sci Med Sci. 2001;56(12):M785‐M789.11723155Blazer DG , Fillenbaum G , Burchett B . The APOE‐E4 allele and the risk of functional decline in a community sample of African American and white older adults. J Gerontol A Biol Sci Med Sci. 2001;56(12):M785‐M789.11723155, Blazer DG , Fillenbaum G , Burchett B . The APOE‐E4 allele and the risk of functional decline in a community sample of African American and white older adults. J Gerontol A Biol Sci Med Sci. 2001;56(12):M785‐M789.11723155
K. Moulder, Sarah Monsell, D. Beekly, Lilah Besser, K. Blennow, W. Kukull, J. Morris (2015)
Factors influencing lumbar puncture participation in Alzheimer’s researchAlzheimer's & Dementia, 11
( Winnock M . Longitudinal analysis of the effect of apolipoprotein E epsilon4 and education on cognitive performance in elderly subjects: the PAQUID study. J Neurol Neurosurg Psychiatry. 2002;72(6):794‐797.12023428)
Winnock M . Longitudinal analysis of the effect of apolipoprotein E epsilon4 and education on cognitive performance in elderly subjects: the PAQUID study. J Neurol Neurosurg Psychiatry. 2002;72(6):794‐797.12023428Winnock M . Longitudinal analysis of the effect of apolipoprotein E epsilon4 and education on cognitive performance in elderly subjects: the PAQUID study. J Neurol Neurosurg Psychiatry. 2002;72(6):794‐797.12023428, Winnock M . Longitudinal analysis of the effect of apolipoprotein E epsilon4 and education on cognitive performance in elderly subjects: the PAQUID study. J Neurol Neurosurg Psychiatry. 2002;72(6):794‐797.12023428
(2018)
epiDisplay: Epidemiological Data Display Package, 2015
RC Team (2017)
R Foundation for Statistical Computing
( Liu C‐C , Kanekiyo T , Xu H , Bu G . Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nat Rev Neurol. 2013;9(2):106‐118.23296339)
Liu C‐C , Kanekiyo T , Xu H , Bu G . Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nat Rev Neurol. 2013;9(2):106‐118.23296339Liu C‐C , Kanekiyo T , Xu H , Bu G . Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nat Rev Neurol. 2013;9(2):106‐118.23296339, Liu C‐C , Kanekiyo T , Xu H , Bu G . Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nat Rev Neurol. 2013;9(2):106‐118.23296339
(2018)
APOE genotypeand cognition in healthy individuals at risk ofAlzheimer ’ s disease : a review
(2019)
pROC: Display and Analyze ROC Curves. 2015
M. Werhane, K. Thomas, E. Edmonds, K. Bangen, My Tran, A. Clark, D. Nation, Paul Gilbert, M. Bondi, L. Delano-Wood (2018)
Differential Effect of APOE ɛ4 Status and Elevated Pulse Pressure on Functional Decline in Cognitively Normal Older Adults.Journal of Alzheimer's disease : JAD, 62 4
( Maruff P , Lim YY , Darby D , et al. Clinical utility of the cogstate brief battery in identifying cognitive impairment in mild cognitive impairment and Alzheimer's disease. BMC Psychol. 2013;1(1):30.25566378)
Maruff P , Lim YY , Darby D , et al. Clinical utility of the cogstate brief battery in identifying cognitive impairment in mild cognitive impairment and Alzheimer's disease. BMC Psychol. 2013;1(1):30.25566378Maruff P , Lim YY , Darby D , et al. Clinical utility of the cogstate brief battery in identifying cognitive impairment in mild cognitive impairment and Alzheimer's disease. BMC Psychol. 2013;1(1):30.25566378, Maruff P , Lim YY , Darby D , et al. Clinical utility of the cogstate brief battery in identifying cognitive impairment in mild cognitive impairment and Alzheimer's disease. BMC Psychol. 2013;1(1):30.25566378
( Langbaum JB , Karlawish J , Roberts JS , et al., GeneMatch: a novel recruitment registry using at‐home APOE genotyping to enhance referrals to Alzheimer's prevention studies. Alzheimer's Dement. 2019;15(4):515‐524.30772251)
Langbaum JB , Karlawish J , Roberts JS , et al., GeneMatch: a novel recruitment registry using at‐home APOE genotyping to enhance referrals to Alzheimer's prevention studies. Alzheimer's Dement. 2019;15(4):515‐524.30772251Langbaum JB , Karlawish J , Roberts JS , et al., GeneMatch: a novel recruitment registry using at‐home APOE genotyping to enhance referrals to Alzheimer's prevention studies. Alzheimer's Dement. 2019;15(4):515‐524.30772251, Langbaum JB , Karlawish J , Roberts JS , et al., GeneMatch: a novel recruitment registry using at‐home APOE genotyping to enhance referrals to Alzheimer's prevention studies. Alzheimer's Dement. 2019;15(4):515‐524.30772251
( Mayeux R , Small SA , Tang M‐X , Tycko B , Stern Y . Memory performance in healthy elderly without Alzheimer's disease: effects of time and apolipoprotein‐E. Neurobiol Aging. 2001;22(4):683‐689.11445269)
Mayeux R , Small SA , Tang M‐X , Tycko B , Stern Y . Memory performance in healthy elderly without Alzheimer's disease: effects of time and apolipoprotein‐E. Neurobiol Aging. 2001;22(4):683‐689.11445269Mayeux R , Small SA , Tang M‐X , Tycko B , Stern Y . Memory performance in healthy elderly without Alzheimer's disease: effects of time and apolipoprotein‐E. Neurobiol Aging. 2001;22(4):683‐689.11445269, Mayeux R , Small SA , Tang M‐X , Tycko B , Stern Y . Memory performance in healthy elderly without Alzheimer's disease: effects of time and apolipoprotein‐E. Neurobiol Aging. 2001;22(4):683‐689.11445269
K. Zhong, J. Cummings (2016)
Healthybrains.org: From Registry to Randomization.The journal of prevention of Alzheimer's disease, 3 3
( Reiman EM , Caselli RJ , Yun LS , et al. Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E. N. Engl J Med. 1996;334(12):752‐758.8592548)
Reiman EM , Caselli RJ , Yun LS , et al. Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E. N. Engl J Med. 1996;334(12):752‐758.8592548Reiman EM , Caselli RJ , Yun LS , et al. Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E. N. Engl J Med. 1996;334(12):752‐758.8592548, Reiman EM , Caselli RJ , Yun LS , et al. Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E. N. Engl J Med. 1996;334(12):752‐758.8592548
( Dagnall CL , Morton LM , Hicks BD , et al. Successful use of whole genome amplified DNA from multiple source types for high‐density Illumina SNP microarrays. BMC Genomics. 2018;19(1):182‐182.29510662)
Dagnall CL , Morton LM , Hicks BD , et al. Successful use of whole genome amplified DNA from multiple source types for high‐density Illumina SNP microarrays. BMC Genomics. 2018;19(1):182‐182.29510662Dagnall CL , Morton LM , Hicks BD , et al. Successful use of whole genome amplified DNA from multiple source types for high‐density Illumina SNP microarrays. BMC Genomics. 2018;19(1):182‐182.29510662, Dagnall CL , Morton LM , Hicks BD , et al. Successful use of whole genome amplified DNA from multiple source types for high‐density Illumina SNP microarrays. BMC Genomics. 2018;19(1):182‐182.29510662
R. Caselli, J. Langbaum, G. Marchant, R. Lindor, Katherine Hunt, Bruce Henslin, A. Dueck, J. Robert (2014)
Public perceptions of presymptomatic testing for Alzheimer disease.Mayo Clinic proceedings, 89 10
( Lahoz C , Schaefer EJ , Cupples LA , et al. Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study. Atherosclerosis. 2001;154(3):529‐537.11257253)
Lahoz C , Schaefer EJ , Cupples LA , et al. Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study. Atherosclerosis. 2001;154(3):529‐537.11257253Lahoz C , Schaefer EJ , Cupples LA , et al. Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study. Atherosclerosis. 2001;154(3):529‐537.11257253, Lahoz C , Schaefer EJ , Cupples LA , et al. Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study. Atherosclerosis. 2001;154(3):529‐537.11257253
( Robin, X , Turck, N , Hainard, A , Lisacek, F , Sanchez, J‐c , & Müller, M (2019). pROC: Display and Analyze ROC Curves. 2015. R package version, 1(4).)
Robin, X , Turck, N , Hainard, A , Lisacek, F , Sanchez, J‐c , & Müller, M (2019). pROC: Display and Analyze ROC Curves. 2015. R package version, 1(4).Robin, X , Turck, N , Hainard, A , Lisacek, F , Sanchez, J‐c , & Müller, M (2019). pROC: Display and Analyze ROC Curves. 2015. R package version, 1(4)., Robin, X , Turck, N , Hainard, A , Lisacek, F , Sanchez, J‐c , & Müller, M (2019). pROC: Display and Analyze ROC Curves. 2015. R package version, 1(4).
( Team RC . R: language and environment for statistical computing R Foundation for Statistical Computing: Vienna, Austria; 2017.)
Team RC . R: language and environment for statistical computing R Foundation for Statistical Computing: Vienna, Austria; 2017.Team RC . R: language and environment for statistical computing R Foundation for Statistical Computing: Vienna, Austria; 2017., Team RC . R: language and environment for statistical computing R Foundation for Statistical Computing: Vienna, Austria; 2017.
( Warnes, GR , Bolker, B , Lumley, T , & Johnson, RC (2018). Various R Programming Tools for Model Fitting. R package version 2.18. 1.)
Warnes, GR , Bolker, B , Lumley, T , & Johnson, RC (2018). Various R Programming Tools for Model Fitting. R package version 2.18. 1.Warnes, GR , Bolker, B , Lumley, T , & Johnson, RC (2018). Various R Programming Tools for Model Fitting. R package version 2.18. 1., Warnes, GR , Bolker, B , Lumley, T , & Johnson, RC (2018). Various R Programming Tools for Model Fitting. R package version 2.18. 1.
Bondi MW (1999)
10.1037/0882-7974.14.2.295Psychol Aging, 14
(2015)
APOE epsilon 4 moderates amyloid - related memory decline in preclinical Alzheimer ’ s disease
(2001)
Apolipoprotein E genotype and cardiovascular disease in the FraminghamHeart Study.Atherosclerosis
(2020)
Brain imagingmeasurements of fibrillar amyloid-beta burden, paired helical filament tau burden, and atrophy in cognitively unimpairedpersonswith two, one, andno copies of the APOE epsilon4 allele
(2021)
Brain health registry GenePool study: A novel approach to online genetics research
( Christensen KD , Karlawish J , Roberts JS , et al. Disclosing genetic risk for Alzheimer's dementia to individuals with mild cognitive impairment. Alzheimer's Dement. 2020;6(1):e12002.)
Christensen KD , Karlawish J , Roberts JS , et al. Disclosing genetic risk for Alzheimer's dementia to individuals with mild cognitive impairment. Alzheimer's Dement. 2020;6(1):e12002.Christensen KD , Karlawish J , Roberts JS , et al. Disclosing genetic risk for Alzheimer's dementia to individuals with mild cognitive impairment. Alzheimer's Dement. 2020;6(1):e12002., Christensen KD , Karlawish J , Roberts JS , et al. Disclosing genetic risk for Alzheimer's dementia to individuals with mild cognitive impairment. Alzheimer's Dement. 2020;6(1):e12002.
( Sumner JA , Hagan K , Grodstein F , Roberts AL , Harel B , Koenen KC . Posttraumatic stress disorder symptoms and cognitive function in a large cohort of middle‐aged women. Depress Anxiety. 2017;34(4):356‐366.28072503)
Sumner JA , Hagan K , Grodstein F , Roberts AL , Harel B , Koenen KC . Posttraumatic stress disorder symptoms and cognitive function in a large cohort of middle‐aged women. Depress Anxiety. 2017;34(4):356‐366.28072503Sumner JA , Hagan K , Grodstein F , Roberts AL , Harel B , Koenen KC . Posttraumatic stress disorder symptoms and cognitive function in a large cohort of middle‐aged women. Depress Anxiety. 2017;34(4):356‐366.28072503, Sumner JA , Hagan K , Grodstein F , Roberts AL , Harel B , Koenen KC . Posttraumatic stress disorder symptoms and cognitive function in a large cohort of middle‐aged women. Depress Anxiety. 2017;34(4):356‐366.28072503
( Moulder KL , Besser LM , Beekly D , et al. Factors influencing lumbar puncture participation in Alzheimer's research. Alzheimer's Dement. 2015;11(7):P780.)
Moulder KL , Besser LM , Beekly D , et al. Factors influencing lumbar puncture participation in Alzheimer's research. Alzheimer's Dement. 2015;11(7):P780.Moulder KL , Besser LM , Beekly D , et al. Factors influencing lumbar puncture participation in Alzheimer's research. Alzheimer's Dement. 2015;11(7):P780., Moulder KL , Besser LM , Beekly D , et al. Factors influencing lumbar puncture participation in Alzheimer's research. Alzheimer's Dement. 2015;11(7):P780.
P. Maruff, Y. Lim, D. Darby, K. Ellis, R. Pietrzak, P. Snyder, A. Bush, C. Szoeke, A. Schembri, D. Ames, C. Masters (2013)
Clinical utility of the cogstate brief battery in identifying cognitive impairment in mild cognitive impairment and Alzheimer’s diseaseBMC psychology, 1
Eunjung Han, P. Carbonetto, Ross Curtis, Yong Wang, J. Granka, J. Byrnes, Keith Noto, Amir Kermany, Natalie Myres, Mathew Barber, K. Rand, Shiya Song, Theodore Roman, E. Battat, Eyal Elyashiv, H. Guturu, Eurie Hong, K. Chahine, C. Ball (2017)
Clustering of 770,000 genomes reveals post-colonial population structure of North AmericaNature Communications, 8
( Revelle W . Psych: Procedures for Personality and Psychological Research. Evanston, Illinois, USA: Northwestern University; 2020.)
Revelle W . Psych: Procedures for Personality and Psychological Research. Evanston, Illinois, USA: Northwestern University; 2020.Revelle W . Psych: Procedures for Personality and Psychological Research. Evanston, Illinois, USA: Northwestern University; 2020., Revelle W . Psych: Procedures for Personality and Psychological Research. Evanston, Illinois, USA: Northwestern University; 2020.
D. Michaelson (2014)
APOE ε4: The most prevalent yet understudied risk factor for Alzheimer's diseaseAlzheimer's & Dementia, 10
( Mackin RS , Insel PS , Truran D , et al. Unsupervised online neuropsychological test performance for individuals with mild cognitive impairment and dementia: results from the Brain Health Registry. Alzheimer's Dement. 2018;10:573‐582.)
Mackin RS , Insel PS , Truran D , et al. Unsupervised online neuropsychological test performance for individuals with mild cognitive impairment and dementia: results from the Brain Health Registry. Alzheimer's Dement. 2018;10:573‐582.Mackin RS , Insel PS , Truran D , et al. Unsupervised online neuropsychological test performance for individuals with mild cognitive impairment and dementia: results from the Brain Health Registry. Alzheimer's Dement. 2018;10:573‐582., Mackin RS , Insel PS , Truran D , et al. Unsupervised online neuropsychological test performance for individuals with mild cognitive impairment and dementia: results from the Brain Health Registry. Alzheimer's Dement. 2018;10:573‐582.
J. Hixson, D. Vernier (1990)
Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI.Journal of lipid research, 31 3
( Werhane ML , Thomas KR , Edmonds EC , et al. Differential Effect of APOE varepsilon4 status and elevated pulse pressure on functional decline in cognitively normal older adults. J Alzheimers Dis. 2018;62(4):1567‐1578.29562507)
Werhane ML , Thomas KR , Edmonds EC , et al. Differential Effect of APOE varepsilon4 status and elevated pulse pressure on functional decline in cognitively normal older adults. J Alzheimers Dis. 2018;62(4):1567‐1578.29562507Werhane ML , Thomas KR , Edmonds EC , et al. Differential Effect of APOE varepsilon4 status and elevated pulse pressure on functional decline in cognitively normal older adults. J Alzheimers Dis. 2018;62(4):1567‐1578.29562507, Werhane ML , Thomas KR , Edmonds EC , et al. Differential Effect of APOE varepsilon4 status and elevated pulse pressure on functional decline in cognitively normal older adults. J Alzheimers Dis. 2018;62(4):1567‐1578.29562507
( Farias ST , Mungas D , Reed BR , et al. The measurement of everyday cognition (ECog): scale development and psychometric properties. Neuropsychology. 2008;22(4):531‐544.18590364)
Farias ST , Mungas D , Reed BR , et al. The measurement of everyday cognition (ECog): scale development and psychometric properties. Neuropsychology. 2008;22(4):531‐544.18590364Farias ST , Mungas D , Reed BR , et al. The measurement of everyday cognition (ECog): scale development and psychometric properties. Neuropsychology. 2008;22(4):531‐544.18590364, Farias ST , Mungas D , Reed BR , et al. The measurement of everyday cognition (ECog): scale development and psychometric properties. Neuropsychology. 2008;22(4):531‐544.18590364
E. Reiman, R. Caselli, L. Yun, Kewei Chen, D. Bandy, S. Minoshima, S. Thibodeau, D. Osborne (1996)
Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E.The New England journal of medicine, 334 12
( Foster JK , Albrecht MA , Savage G , et al., Lack of reliable evidence for a distinctive epsilon4‐related cognitive phenotype that is independent from clinical diagnostic status: findings from the Australian imaging, biomarkers and lifestyle study. Brain. 2013;136(Pt 7):2201‐2216.23737466)
Foster JK , Albrecht MA , Savage G , et al., Lack of reliable evidence for a distinctive epsilon4‐related cognitive phenotype that is independent from clinical diagnostic status: findings from the Australian imaging, biomarkers and lifestyle study. Brain. 2013;136(Pt 7):2201‐2216.23737466Foster JK , Albrecht MA , Savage G , et al., Lack of reliable evidence for a distinctive epsilon4‐related cognitive phenotype that is independent from clinical diagnostic status: findings from the Australian imaging, biomarkers and lifestyle study. Brain. 2013;136(Pt 7):2201‐2216.23737466, Foster JK , Albrecht MA , Savage G , et al., Lack of reliable evidence for a distinctive epsilon4‐related cognitive phenotype that is independent from clinical diagnostic status: findings from the Australian imaging, biomarkers and lifestyle study. Brain. 2013;136(Pt 7):2201‐2216.23737466
(2020)
Effects of gender, race, ethnicity, education on online aging research participation
( Ashford MT , Eichenbaum J , Williams T , et al. Effects of gender, race, ethnicity, education on online aging research participation. Alzheimer's Dement. 2020;6(1):e12028.)
Ashford MT , Eichenbaum J , Williams T , et al. Effects of gender, race, ethnicity, education on online aging research participation. Alzheimer's Dement. 2020;6(1):e12028.Ashford MT , Eichenbaum J , Williams T , et al. Effects of gender, race, ethnicity, education on online aging research participation. Alzheimer's Dement. 2020;6(1):e12028., Ashford MT , Eichenbaum J , Williams T , et al. Effects of gender, race, ethnicity, education on online aging research participation. Alzheimer's Dement. 2020;6(1):e12028.
( Gooblar J , Roe CM , Selsor NJ , Gabel MJ , Morris JC . Attitudes of research participants and the general public regarding disclosure of alzheimer disease research results. JAMA Neurol. 2015;72(12):1484‐1490.26501506)
Gooblar J , Roe CM , Selsor NJ , Gabel MJ , Morris JC . Attitudes of research participants and the general public regarding disclosure of alzheimer disease research results. JAMA Neurol. 2015;72(12):1484‐1490.26501506Gooblar J , Roe CM , Selsor NJ , Gabel MJ , Morris JC . Attitudes of research participants and the general public regarding disclosure of alzheimer disease research results. JAMA Neurol. 2015;72(12):1484‐1490.26501506, Gooblar J , Roe CM , Selsor NJ , Gabel MJ , Morris JC . Attitudes of research participants and the general public regarding disclosure of alzheimer disease research results. JAMA Neurol. 2015;72(12):1484‐1490.26501506
Chia-Chen Liu, T. Kanekiyo, Huaxi Xu, G. Bu (2013)
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapyNature Reviews Neurology, 9
( Tung JY , Do CB , Hinds DA , et al. Efficient replication of over 180 genetic associations with self‐reported medical data. PLoS One. 2011;6(8):e23473.21858135)
Tung JY , Do CB , Hinds DA , et al. Efficient replication of over 180 genetic associations with self‐reported medical data. PLoS One. 2011;6(8):e23473.21858135Tung JY , Do CB , Hinds DA , et al. Efficient replication of over 180 genetic associations with self‐reported medical data. PLoS One. 2011;6(8):e23473.21858135, Tung JY , Do CB , Hinds DA , et al. Efficient replication of over 180 genetic associations with self‐reported medical data. PLoS One. 2011;6(8):e23473.21858135
Sterling Johnson, R. Koscik, E. Jonaitis, L. Clark, Kimberly Mueller, S. Berman, B. Bendlin, C. Engelman, O. Okonkwo, K. Hogan, S. Asthana, C. Carlsson, B. Hermann, M. Sager (2017)
The Wisconsin Registry for Alzheimer's Prevention: A review of findings and current directionsAlzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, 10
( Qian J , Wolters FJ , Beiser A , et al. APOE‐related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts. PLoS Med. 2017;14(3):e1002254.28323826)
Qian J , Wolters FJ , Beiser A , et al. APOE‐related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts. PLoS Med. 2017;14(3):e1002254.28323826Qian J , Wolters FJ , Beiser A , et al. APOE‐related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts. PLoS Med. 2017;14(3):e1002254.28323826, Qian J , Wolters FJ , Beiser A , et al. APOE‐related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts. PLoS Med. 2017;14(3):e1002254.28323826
( Knight RG , Tsui HSL , Abraham WC , et al. Lack of effect of the apolipoprotein E epsilon4 genotype on cognition during healthy aging. J Clin Exp Neuropsychol. 2014;36(7):742‐750.25026037)
Knight RG , Tsui HSL , Abraham WC , et al. Lack of effect of the apolipoprotein E epsilon4 genotype on cognition during healthy aging. J Clin Exp Neuropsychol. 2014;36(7):742‐750.25026037Knight RG , Tsui HSL , Abraham WC , et al. Lack of effect of the apolipoprotein E epsilon4 genotype on cognition during healthy aging. J Clin Exp Neuropsychol. 2014;36(7):742‐750.25026037, Knight RG , Tsui HSL , Abraham WC , et al. Lack of effect of the apolipoprotein E epsilon4 genotype on cognition during healthy aging. J Clin Exp Neuropsychol. 2014;36(7):742‐750.25026037
Lahoz C (2001)
10.1016/S0021-9150(00)00570-0Atherosclerosis, 154
C. Dagnall, L. Morton, B. Hicks, Shengchao Li, Weiyin Zhou, E. Karlins, Kedest Teshome, Salma Chowdhury, K. Lashley, J. Sampson, L. Robison, G. Armstrong, S. Bhatia, G. Radloff, S. Davies, M. Tucker, M. Yeager, S. Chanock (2018)
Successful use of whole genome amplified DNA from multiple source types for high-density Illumina SNP microarraysBMC Genomics, 19
M. Weiner, R. Nosheny, M. Camacho, Diana Truran-Sacrey, R. Mackin, D. Flenniken, A. Ulbricht, Philip Insel, Shannon Finley, J. Fockler, D. Veitch (2018)
The Brain Health Registry: An internet-based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studiesAlzheimer's & Dementia, 14
M. Tang, Y. Stern, K. Marder, K. Bell, B. Gurland, R. Lantigua, H. Andrews, Lin Feng, B. Tycko, R. Mayeux (2001)
The APOE- (cid:101) 4 Allele and the Risk of Alzheimer Disease Among African Americans, Whites, and Hispanics
D. Lyall, J. Ward, Stuart Ritchie, G. Davies, B. Cullen, Carlos Celis, M. Bailey, Jana Anderson, Jonathan Evans, Daniel Mckay, A. McIntosh, N. Sattar, Danny Smith, I. Deary, J. Pell (2016)
Alzheimer disease genetic risk factor APOE e4 and cognitive abilities in 111,739 UK Biobank participants.Age and ageing, 45 4
R. Green, R. Green, J. Roberts, L. Cupples, N. Relkin, P. Whitehouse, Tamsen Brown, S. Eckert, M. Butson, A. Sadovnick, K. Quaid, Clara Chen, R. Cook-Deegan, L. Farrer (2009)
Disclosure of APOE genotype for risk of Alzheimer's disease.The New England journal of medicine, 361 3
( Hixson JE , and Vernier DT . Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res. 1990;31(3):545‐548.2341813)
Hixson JE , and Vernier DT . Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res. 1990;31(3):545‐548.2341813Hixson JE , and Vernier DT . Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res. 1990;31(3):545‐548.2341813, Hixson JE , and Vernier DT . Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res. 1990;31(3):545‐548.2341813
( Jansen WJ , Ossenkoppele R , Knol DL , et al. Prevalence of cerebral amyloid pathology in persons without dementia: a meta‐analysis. JAMA. 2015;313(19):1924‐1938.25988462)
Jansen WJ , Ossenkoppele R , Knol DL , et al. Prevalence of cerebral amyloid pathology in persons without dementia: a meta‐analysis. JAMA. 2015;313(19):1924‐1938.25988462Jansen WJ , Ossenkoppele R , Knol DL , et al. Prevalence of cerebral amyloid pathology in persons without dementia: a meta‐analysis. JAMA. 2015;313(19):1924‐1938.25988462, Jansen WJ , Ossenkoppele R , Knol DL , et al. Prevalence of cerebral amyloid pathology in persons without dementia: a meta‐analysis. JAMA. 2015;313(19):1924‐1938.25988462
Wei Sng, S. Yeo, Bernice Lin, Tih-Shih Lee (2019)
Impacts of apolipoprotein E disclosure on healthy Asian older adults: a cohort studyInternational Psychogeriatrics, 31
( Rajan KB , Barnes LL , Wilson RS , Weuve J , Mcaninch EA , Evans DA . Apolipoprotein E Genotypes, age, race, and cognitive decline in a population sample. J Am Geriatr Soc. 2019;67(4):734‐740.30584655)
Rajan KB , Barnes LL , Wilson RS , Weuve J , Mcaninch EA , Evans DA . Apolipoprotein E Genotypes, age, race, and cognitive decline in a population sample. J Am Geriatr Soc. 2019;67(4):734‐740.30584655Rajan KB , Barnes LL , Wilson RS , Weuve J , Mcaninch EA , Evans DA . Apolipoprotein E Genotypes, age, race, and cognitive decline in a population sample. J Am Geriatr Soc. 2019;67(4):734‐740.30584655, Rajan KB , Barnes LL , Wilson RS , Weuve J , Mcaninch EA , Evans DA . Apolipoprotein E Genotypes, age, race, and cognitive decline in a population sample. J Am Geriatr Soc. 2019;67(4):734‐740.30584655
J. Qian, F. Wolters, A. Beiser, M. Haan, M. Ikram, J. Karlawish, J. Langbaum, J. Neuhaus, E. Reiman, J. Roberts, S. Seshadri, P. Tariot, Beth Woods, R. Betensky, D. Blacker, Harvard Chan (2017)
APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohortsPLoS Medicine, 14
K. Yaffe, J. Cauley, L. Sands, W. Browner (1997)
Apolipoprotein E phenotype and cognitive decline in a prospective study of elderly community women.Archives of neurology, 54 9
( Lyall DM , Ward J , Ritchie SJ , et al. Alzheimer disease genetic risk factor APOE e4 and cognitive abilities in 111,739 UK Biobank participants. Age Ageing. 2016;45(4):511‐517.27103599)
Lyall DM , Ward J , Ritchie SJ , et al. Alzheimer disease genetic risk factor APOE e4 and cognitive abilities in 111,739 UK Biobank participants. Age Ageing. 2016;45(4):511‐517.27103599Lyall DM , Ward J , Ritchie SJ , et al. Alzheimer disease genetic risk factor APOE e4 and cognitive abilities in 111,739 UK Biobank participants. Age Ageing. 2016;45(4):511‐517.27103599, Lyall DM , Ward J , Ritchie SJ , et al. Alzheimer disease genetic risk factor APOE e4 and cognitive abilities in 111,739 UK Biobank participants. Age Ageing. 2016;45(4):511‐517.27103599
W. Revelle (2017)
psych: Procedures for Personality and Psychological Research
( Weiner MW , Nosheny R , Camacho M , et al. The brain health registry: an internet‐based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies. Alzheimer's Dement. 2018;14(8):1063‐1076.29754989)
Weiner MW , Nosheny R , Camacho M , et al. The brain health registry: an internet‐based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies. Alzheimer's Dement. 2018;14(8):1063‐1076.29754989Weiner MW , Nosheny R , Camacho M , et al. The brain health registry: an internet‐based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies. Alzheimer's Dement. 2018;14(8):1063‐1076.29754989, Weiner MW , Nosheny R , Camacho M , et al. The brain health registry: an internet‐based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies. Alzheimer's Dement. 2018;14(8):1063‐1076.29754989
MBChB Hendrie, PhD Hall, PhD' Hui, PhD Unverzagt, PhD Yu, PhD' Lahiri, PhD Sahota, MD Farlow, Musick, MD Class, A. Brashear, MD Burdine, MD Osuntokun, MD Ogunniyi, MD Gureje, MD Baiyewu, PhDS Schellenberg, D. Hendrie (1995)
Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African AmericansAnnals of Neurology, 37
( Michaelson DM . APOE ε4: the most prevalent yet understudied risk factor for Alzheimer's disease. Alzheimer's Dement. 2014;10(6):861‐868.25217293)
Michaelson DM . APOE ε4: the most prevalent yet understudied risk factor for Alzheimer's disease. Alzheimer's Dement. 2014;10(6):861‐868.25217293Michaelson DM . APOE ε4: the most prevalent yet understudied risk factor for Alzheimer's disease. Alzheimer's Dement. 2014;10(6):861‐868.25217293, Michaelson DM . APOE ε4: the most prevalent yet understudied risk factor for Alzheimer's disease. Alzheimer's Dement. 2014;10(6):861‐868.25217293
( Oveisgharan S , Buchman AS , Yu L , et al. APOE epsilon2epsilon4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults. Neurology. 2018;90(24):e2127‐e2134.29752306)
Oveisgharan S , Buchman AS , Yu L , et al. APOE epsilon2epsilon4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults. Neurology. 2018;90(24):e2127‐e2134.29752306Oveisgharan S , Buchman AS , Yu L , et al. APOE epsilon2epsilon4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults. Neurology. 2018;90(24):e2127‐e2134.29752306, Oveisgharan S , Buchman AS , Yu L , et al. APOE epsilon2epsilon4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults. Neurology. 2018;90(24):e2127‐e2134.29752306
R. Knight, Helen Tsui, W. Abraham, C. Skeaff, Jennifer McMahon, Nick Cutfield (2014)
Lack of effect of the apolipoprotein E ε4 genotype on cognition during healthy agingJournal of Clinical and Experimental Neuropsychology, 36
M. Winnock, L. Letenneur, H. Jacqmin-Gadda, J. Dallongeville, P. Amouyel, J. Dartigues (2002)
Longitudinal analysis of the effect of apolipoprotein E ε4 and education on cognitive performance in elderly subjects: the PAQUID studyJournal of Neurology, Neurosurgery & Psychiatry, 72
J. Langbaum, N. High, J. Nichols, C. Kettenhoven, E. Reiman, P. Tariot (2020)
The Alzheimer’s Prevention Registry: A Large Internet-Based Participant Recruitment Registry to Accelerate Referrals to Alzheimer’s-Focused StudiesThe Journal of Prevention of Alzheimer's Disease
M. Mielke, M. Machulda, Clinton Hagen, T. Christianson, R. Roberts, D. Knopman, P. Vemuri, V. Lowe, W. Kremers, C. Jack, R. Petersen (2016)
Influence of amyloid and APOE on cognitive performance in a late middle-aged cohortAlzheimer's & Dementia, 12
( Holtzman DM , Herz J , Bu G . Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. Cold Spring Harb Perspect Med. 2012;2(3):a006312.22393530)
Holtzman DM , Herz J , Bu G . Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. Cold Spring Harb Perspect Med. 2012;2(3):a006312.22393530Holtzman DM , Herz J , Bu G . Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. Cold Spring Harb Perspect Med. 2012;2(3):a006312.22393530, Holtzman DM , Herz J , Bu G . Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. Cold Spring Harb Perspect Med. 2012;2(3):a006312.22393530
( Eriksson N , Macpherson JM , Tung JY , et al. Web‐based, participant‐driven studies yield novel genetic associations for common traits. PLos Genet. 2010;6(6):e1000993.20585627)
Eriksson N , Macpherson JM , Tung JY , et al. Web‐based, participant‐driven studies yield novel genetic associations for common traits. PLos Genet. 2010;6(6):e1000993.20585627Eriksson N , Macpherson JM , Tung JY , et al. Web‐based, participant‐driven studies yield novel genetic associations for common traits. PLos Genet. 2010;6(6):e1000993.20585627, Eriksson N , Macpherson JM , Tung JY , et al. Web‐based, participant‐driven studies yield novel genetic associations for common traits. PLos Genet. 2010;6(6):e1000993.20585627
K. Rajan, L. Barnes, R. Wilson, J. Weuve, Elizabeth McAninch, Denis Evans (2018)
Apolipoprotein E Genotypes, Age, Race, and Cognitive Decline in a Population SampleJournal of the American Geriatrics Society, 67
J. Foster, M. Albrecht, G. Savage, N. Lautenschlager, K. Ellis, P. Maruff, C. Szoeke, K. Taddei, R. Martins, C. Masters, D. Ames (2013)
Lack of reliable evidence for a distinctive ε4-related cognitive phenotype that is independent from clinical diagnostic status: findings from the Australian Imaging, Biomarkers and Lifestyle Study.Brain : a journal of neurology, 136 Pt 7
K. Christensen, J. Karlawish, J. Roberts, W. Uhlmann, K. Harkins, Elisabeth Wood, T. Obisesan, Lan Le, L. Cupples, Emilie Zoltick, Megan Johnson, Margaret Bradbury, L. Waterston, Clara Chen, Sara Feldman, Denise Perry, Robert Green (2020)
Disclosing genetic risk for Alzheimer's dementia to individuals with mild cognitive impairmentAlzheimer's & Dementia : Translational Research & Clinical Interventions, 6
S. Farias, D. Mungas, B. Reed, D. Cahn-Weiner, W. Jagust, K. Baynes, C. DeCarli (2008)
The measurement of everyday cognition (ECog): scale development and psychometric properties.Neuropsychology, 22 4
The following entities have provided funding for academic travel: Kenes Intl
D. Holtzman, J. Herz, G. Bu (2012)
Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease.Cold Spring Harbor perspectives in medicine, 2 3
P. Maruff, Elizabeth Thomas, L. Cysique, B. Brew, A. Collie, P. Snyder, R. Pietrzak (2009)
Validity of the CogState brief battery: relationship to standardized tests and sensitivity to cognitive impairment in mild traumatic brain injury, schizophrenia, and AIDS dementia complex.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, 24 2
Willemijn Jansen, R. Ossenkoppele, D. Knol, B. Tijms, P. Scheltens, F. Verhey, P. Visser, P. Aalten, D. Aarsland, D. Alcolea, M. Alexander, I. Almdahl, S. Arnold, I. Baldeiras, H. Barthel, B. Berckel, K. Bibeau, K. Blennow, D. Brooks, M. Buchem, V. Camus, E. Cavedo, Kewei Chen, G. Chételat, A. Cohen, A. Drzezga, S. Engelborghs, A. Fagan, T. Fladby, A. Fleisher, W. Flier, L. Ford, S. Förster, J. Fortea, N. Foskett, K. Frederiksen, Y. Freund-Levi, G. Frisoni, L. Froelich, T. Gabryelewicz, K. Gill, O. Gkatzima, E. Gómez-Tortosa, M. Gordon, T. Grimmer, H. Hampel, L. Hausner, S. Hellwig, S. Herukka, H. Hildebrandt, L. Ishihara, A. Ivanoiu, W. Jagust, P. Johannsen, R. Kandimalla, E. Kapaki, A. Klimkowicz-Mrowiec, W. Klunk, S. Köhler, N. Koglin, J. Kornhuber, M. Kramberger, K. Laere, S. Landau, D. Lee, M. Leon, Viviana Lisetti, A. Lleó, K. Madsen, W. Maier, J. Marcusson, N. Mattsson, A. Mendonça, O. Meulenbroek, P. Meyer, M. Mintun, V. Mok, J. Molinuevo, H. Møllergård, J. Morris, B. Mroczko, S. Mussele, D. Na, A. Newberg, A. Nordberg, A. Nordlund, G. Novak, G. Paraskevas, L. Parnetti, G. Perera, O. Peters, J. Popp, S. Prabhakar, G. Rabinovici, I. Ramakers, L. Rami, Catarina Oliveira, J. Rinne, K. Rodrigue, E. Rodríguez-Rodríguez, C. Roe, U. Rot, C. Rowe, E. Rüther, O. Sabri, P. Sánchez-Juan, I. Santana, M. Sarazin, J. Schröder, Christin Schütte, S. Seo, F. Soetewey, H. Soininen, L. Spiru, H. Struyfs, C. Teunissen, M. Tsolaki, R. Vandenberghe, M. Verbeek, V. Villemagne, S. Vos, Linda Doorn, G. Waldemar, A. Wallin, Å. Wallin, J. Wiltfang, D. Wolk, M. Zboch, H. Zetterberg (2015)
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.JAMA, 313 19
J. Tung, Chuong Do, D. Hinds, A. Kiefer, J. Macpherson, A. Chowdry, U. Francke, Brian Naughton, J. Mountain, A. Wojcicki, N. Eriksson, P. Reitsma (2011)
Efficient Replication of over 180 Genetic Associations with Self-Reported Medical DataPLoS ONE, 6
( Chongsuvivatwong, V (2018). epiDisplay: Epidemiological Data Display Package, 2015. R package version, 3(2.0).)
Chongsuvivatwong, V (2018). epiDisplay: Epidemiological Data Display Package, 2015. R package version, 3(2.0).Chongsuvivatwong, V (2018). epiDisplay: Epidemiological Data Display Package, 2015. R package version, 3(2.0)., Chongsuvivatwong, V (2018). epiDisplay: Epidemiological Data Display Package, 2015. R package version, 3(2.0).
( Yao RA , Akinrinade O , Chaix M , Mital S . Quality of whole genome sequencing from blood versus saliva derived DNA in cardiac patients. BMC Med Genet. 2020;13(1):11‐11.)
Yao RA , Akinrinade O , Chaix M , Mital S . Quality of whole genome sequencing from blood versus saliva derived DNA in cardiac patients. BMC Med Genet. 2020;13(1):11‐11.Yao RA , Akinrinade O , Chaix M , Mital S . Quality of whole genome sequencing from blood versus saliva derived DNA in cardiac patients. BMC Med Genet. 2020;13(1):11‐11., Yao RA , Akinrinade O , Chaix M , Mital S . Quality of whole genome sequencing from blood versus saliva derived DNA in cardiac patients. BMC Med Genet. 2020;13(1):11‐11.
R. Nosheny, M. Camacho, Philip Insel, D. Flenniken, J. Fockler, D. Truran, Shannon Finley, A. Ulbricht, P. Maruff, K. Yaffe, R. Mackin, M. Weiner (2018)
Online study partner-reported cognitive decline in the Brain Health RegistryAlzheimer's & Dementia : Translational Research & Clinical Interventions, 4
( Yaffe K , Cauley J , Sands L , Browner W . Apolipoprotein E phenotype and cognitive decline in a prospective study of elderly community women. Arch Neurol. 1997;54(9):1110‐1114.9311354)
Yaffe K , Cauley J , Sands L , Browner W . Apolipoprotein E phenotype and cognitive decline in a prospective study of elderly community women. Arch Neurol. 1997;54(9):1110‐1114.9311354Yaffe K , Cauley J , Sands L , Browner W . Apolipoprotein E phenotype and cognitive decline in a prospective study of elderly community women. Arch Neurol. 1997;54(9):1110‐1114.9311354, Yaffe K , Cauley J , Sands L , Browner W . Apolipoprotein E phenotype and cognitive decline in a prospective study of elderly community women. Arch Neurol. 1997;54(9):1110‐1114.9311354
( Green RC , Roberts JS , Cupples LA . Disclosure of APOE genotype for risk of Alzheimer's disease. N Engl J Med. 2009;361(3):245‐254.19605829)
Green RC , Roberts JS , Cupples LA . Disclosure of APOE genotype for risk of Alzheimer's disease. N Engl J Med. 2009;361(3):245‐254.19605829Green RC , Roberts JS , Cupples LA . Disclosure of APOE genotype for risk of Alzheimer's disease. N Engl J Med. 2009;361(3):245‐254.19605829, Green RC , Roberts JS , Cupples LA . Disclosure of APOE genotype for risk of Alzheimer's disease. N Engl J Med. 2009;361(3):245‐254.19605829
J. Sumner, K. Hagan, F. Grodstein, A. Roberts, B. Harel, K. Koenen (2017)
Posttraumatic stress disorder symptoms and cognitive function in a large cohort of middle‐aged womenDepression and Anxiety, 34
( Bardach SH , Jicha GA , Karanth S , Zhang X , Abner EL . Genetic sample provision among National Alzheimer's Coordinating Center participants. J Alzheimer's Dis. 2019;69:123‐133.30958359)
Bardach SH , Jicha GA , Karanth S , Zhang X , Abner EL . Genetic sample provision among National Alzheimer's Coordinating Center participants. J Alzheimer's Dis. 2019;69:123‐133.30958359Bardach SH , Jicha GA , Karanth S , Zhang X , Abner EL . Genetic sample provision among National Alzheimer's Coordinating Center participants. J Alzheimer's Dis. 2019;69:123‐133.30958359, Bardach SH , Jicha GA , Karanth S , Zhang X , Abner EL . Genetic sample provision among National Alzheimer's Coordinating Center participants. J Alzheimer's Dis. 2019;69:123‐133.30958359
( Nosheny RL , Camacho MR , Insel PS , et al. Online study partner‐reported cognitive decline in the Brain Health Registry. Alzheimers Dement (N Y). 2018;4:565‐574.30386821)
Nosheny RL , Camacho MR , Insel PS , et al. Online study partner‐reported cognitive decline in the Brain Health Registry. Alzheimers Dement (N Y). 2018;4:565‐574.30386821Nosheny RL , Camacho MR , Insel PS , et al. Online study partner‐reported cognitive decline in the Brain Health Registry. Alzheimers Dement (N Y). 2018;4:565‐574.30386821, Nosheny RL , Camacho MR , Insel PS , et al. Online study partner‐reported cognitive decline in the Brain Health Registry. Alzheimers Dement (N Y). 2018;4:565‐574.30386821
F. Wolters, Qiong Yang, M. Biggs, J. Jakobsdóttir, Shuo Li, Daniel Evans, J. Bis, T. Harris, R. Vasan, Nuno Zilhao, M. Ghanbari, M. Ikram, L. Launer, B. Psaty, G. Tranah, A. Kulminski, V. Gudnason, S. Seshadri (2019)
The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE)PLoS ONE, 14
J. Kuiper, R. Voshaar, F. Verhoeven, S. Zuidema, N. Smidt (2017)
Comparison of cognitive functioning as measured by the Ruff Figural Fluency Test and the CogState computerized battery within the LifeLines Cohort StudyBMC Psychology, 5
R. Mayeux, S. Small, M. Tang, B. Tycko, Y. Stern (2001)
Memory performance in healthy elderly without Alzheimer’s disease: effects of time and apolipoprotein-ENeurobiology of Aging, 22
R. Mackin, Philip Insel, D. Truran, Shannon Finley, D. Flenniken, R. Nosheny, Aaron Ulbright, Monica Comacho, David Bickford, B. Harel, P. Maruff, M. Weiner (2018)
Unsupervised online neuropsychological test performance for individuals with mild cognitive impairment and dementia: Results from the Brain Health RegistryAlzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, 10
( Kuiper JS , Oude Voshaar RC , Verhoeven FEA , et al. Comparison of cognitive functioning as measured by the Ruff Figural Fluency Test and the CogState computerized battery within the LifeLines Cohort Study. BMC Psychol. 2017;5(1):15.28494817)
Kuiper JS , Oude Voshaar RC , Verhoeven FEA , et al. Comparison of cognitive functioning as measured by the Ruff Figural Fluency Test and the CogState computerized battery within the LifeLines Cohort Study. BMC Psychol. 2017;5(1):15.28494817Kuiper JS , Oude Voshaar RC , Verhoeven FEA , et al. Comparison of cognitive functioning as measured by the Ruff Figural Fluency Test and the CogState computerized battery within the LifeLines Cohort Study. BMC Psychol. 2017;5(1):15.28494817, Kuiper JS , Oude Voshaar RC , Verhoeven FEA , et al. Comparison of cognitive functioning as measured by the Ruff Figural Fluency Test and the CogState computerized battery within the LifeLines Cohort Study. BMC Psychol. 2017;5(1):15.28494817
( Tang M‐X . The APOE‐epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics. JAMA. 1998;279(10):751‐75.9508150)
Tang M‐X . The APOE‐epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics. JAMA. 1998;279(10):751‐75.9508150Tang M‐X . The APOE‐epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics. JAMA. 1998;279(10):751‐75.9508150, Tang M‐X . The APOE‐epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics. JAMA. 1998;279(10):751‐75.9508150
RG Knight, HSL Tsui, WC Abraham (2014)
Lack of effect of the apolipoprotein E epsilon4 genotype on cognition during healthy aging, 36
( Mielke MM , Machulda MM , Hagen CE , et al. Influence of amyloid and APOE on cognitive performance in a late middle‐aged cohort. Alzheimers Dement. 2016;12(3):281‐291.26602629)
Mielke MM , Machulda MM , Hagen CE , et al. Influence of amyloid and APOE on cognitive performance in a late middle‐aged cohort. Alzheimers Dement. 2016;12(3):281‐291.26602629Mielke MM , Machulda MM , Hagen CE , et al. Influence of amyloid and APOE on cognitive performance in a late middle‐aged cohort. Alzheimers Dement. 2016;12(3):281‐291.26602629, Mielke MM , Machulda MM , Hagen CE , et al. Influence of amyloid and APOE on cognitive performance in a late middle‐aged cohort. Alzheimers Dement. 2016;12(3):281‐291.26602629
C Lahoz, EJ Schaefer, LA Cupples (2001)
Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study, 154
( Grill JD , Hoang D , Gillen DL , et al. Constructing a local potential participant registry to improve Alzheimer's disease clinical research recruitment. J Alzheimers Dis. 2018;63(3):1055‐1063.29710723)
Grill JD , Hoang D , Gillen DL , et al. Constructing a local potential participant registry to improve Alzheimer's disease clinical research recruitment. J Alzheimers Dis. 2018;63(3):1055‐1063.29710723Grill JD , Hoang D , Gillen DL , et al. Constructing a local potential participant registry to improve Alzheimer's disease clinical research recruitment. J Alzheimers Dis. 2018;63(3):1055‐1063.29710723, Grill JD , Hoang D , Gillen DL , et al. Constructing a local potential participant registry to improve Alzheimer's disease clinical research recruitment. J Alzheimers Dis. 2018;63(3):1055‐1063.29710723
( Cromer JA , Harel BT , Yu K , et al. Comparison of cognitive performance on the cogstate brief battery when taken in‐clinic, in‐group, and unsupervised. Clin Neuropsychol. 2015;29(4):542‐558.26165425)
Cromer JA , Harel BT , Yu K , et al. Comparison of cognitive performance on the cogstate brief battery when taken in‐clinic, in‐group, and unsupervised. Clin Neuropsychol. 2015;29(4):542‐558.26165425Cromer JA , Harel BT , Yu K , et al. Comparison of cognitive performance on the cogstate brief battery when taken in‐clinic, in‐group, and unsupervised. Clin Neuropsychol. 2015;29(4):542‐558.26165425, Cromer JA , Harel BT , Yu K , et al. Comparison of cognitive performance on the cogstate brief battery when taken in‐clinic, in‐group, and unsupervised. Clin Neuropsychol. 2015;29(4):542‐558.26165425
(2017)
R: language and environment for statistical computing. R Foundation for Statistical Computing
( Ghisays V , Goradia DD , Protas H , et al. Brain imaging measurements of fibrillar amyloid‐beta burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE epsilon4 allele. Alzheimers Dement. 2020;16(4):598‐609.31831374)
Ghisays V , Goradia DD , Protas H , et al. Brain imaging measurements of fibrillar amyloid‐beta burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE epsilon4 allele. Alzheimers Dement. 2020;16(4):598‐609.31831374Ghisays V , Goradia DD , Protas H , et al. Brain imaging measurements of fibrillar amyloid‐beta burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE epsilon4 allele. Alzheimers Dement. 2020;16(4):598‐609.31831374, Ghisays V , Goradia DD , Protas H , et al. Brain imaging measurements of fibrillar amyloid‐beta burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE epsilon4 allele. Alzheimers Dement. 2020;16(4):598‐609.31831374
( Sng WT , Yeo SiN , Lin BX , Lee T‐S . Impacts of apolipoprotein E disclosure on healthy Asian older adults: a cohort study. Int Psychogeriatr. 2019;31(10):1499‐1507.30894233)
Sng WT , Yeo SiN , Lin BX , Lee T‐S . Impacts of apolipoprotein E disclosure on healthy Asian older adults: a cohort study. Int Psychogeriatr. 2019;31(10):1499‐1507.30894233Sng WT , Yeo SiN , Lin BX , Lee T‐S . Impacts of apolipoprotein E disclosure on healthy Asian older adults: a cohort study. Int Psychogeriatr. 2019;31(10):1499‐1507.30894233, Sng WT , Yeo SiN , Lin BX , Lee T‐S . Impacts of apolipoprotein E disclosure on healthy Asian older adults: a cohort study. Int Psychogeriatr. 2019;31(10):1499‐1507.30894233
( Wolters FJ , Yang Q , Biggs ML , et al. The impact of APOE genotype on survival: results of 38,537 participants from six population‐based cohorts (E2‐CHARGE). PLoS One. 2019;14(7):e0219668.31356640)
Wolters FJ , Yang Q , Biggs ML , et al. The impact of APOE genotype on survival: results of 38,537 participants from six population‐based cohorts (E2‐CHARGE). PLoS One. 2019;14(7):e0219668.31356640Wolters FJ , Yang Q , Biggs ML , et al. The impact of APOE genotype on survival: results of 38,537 participants from six population‐based cohorts (E2‐CHARGE). PLoS One. 2019;14(7):e0219668.31356640, Wolters FJ , Yang Q , Biggs ML , et al. The impact of APOE genotype on survival: results of 38,537 participants from six population‐based cohorts (E2‐CHARGE). PLoS One. 2019;14(7):e0219668.31356640
Alzheimer's & Dementia: Translational Research & Clinical Interventions – Wiley
Published: Jan 1, 2021
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