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Bernstein's and gene‐counting methods in generalized ABO‐like systems

Bernstein's and gene‐counting methods in generalized ABO‐like systems Summary Although the simple and adjusted Bernstein's methods are fully efficient for m = 2 and m = 3 (ABO system) respectively, their efficiency declines for larger values of m. For m 4, the adjusted or modified Bernstein's method with a single counting iteration leads to a nearly efficient estimator. A single degree of freedom chi‐square test of the Hardy‐Weinberg law for all m is derived. Some findings on the statistical efficiency of typing various numbers of antigens are given. All the results are illustrated in numerical examples. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

Bernstein's and gene‐counting methods in generalized ABO‐like systems

Annals of Human Genetics , Volume 39 (3) – Jan 1, 1976

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References (13)

Publisher
Wiley
Copyright
Copyright © 1976 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1111/j.1469-1809.1976.tb00141.x
Publisher site
See Article on Publisher Site

Abstract

Summary Although the simple and adjusted Bernstein's methods are fully efficient for m = 2 and m = 3 (ABO system) respectively, their efficiency declines for larger values of m. For m 4, the adjusted or modified Bernstein's method with a single counting iteration leads to a nearly efficient estimator. A single degree of freedom chi‐square test of the Hardy‐Weinberg law for all m is derived. Some findings on the statistical efficiency of typing various numbers of antigens are given. All the results are illustrated in numerical examples.

Journal

Annals of Human GeneticsWiley

Published: Jan 1, 1976

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