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References (8)
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STUDIES ON THE USE OF IN VITRO PROCEDURES FOR THE SCREENING OF POTENTIAL ANTITUMOR AGENTS: COMPARISON OF ACTIVITY IN MAMMALIAN CELL CULTURES AND MICROBIOLOGICAL ASSAYS ALONE AND IN COMBINATION WITH EXPERIMENTAL ANTITUMOR ACTIVITY *Annals of the New York Academy of Sciences, 76
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- Publisher
- Wiley
- Copyright
- Copyright © 1976 Wiley Subscription Services, Inc., A Wiley Company
- ISSN
- 0323-4320
- eISSN
- 1521-401X
- DOI
- 10.1002/aheh.19760040111
- Publisher site
- See Article on Publisher Site
Abstract
The method of determining toxicity in streams by the use of axenic cultures of the protozons species Tetrahymena pyriformis is described. Contrary to the similar tests which are used in medicine in defined but rather complicated culture media, for the toxicological experiments in surface water it is possible to use very simple media for the cultivation of test organisms. Duration of the whole direct test of toxicity is limited to 24 hours. The other advantages of using the test organism Tetrahymena pyriformis are mentioned as well. According to the agricultural and industrial pollution which often takes place in our surface waters five chemicals, most of them pesticides, were tested.
Journal
Acta hydrochimica et hydrobiologica – Wiley
Published: Jan 1, 1976