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Assignment of the polymorphic intestinal mucin gene (MUC2) to chromosome 11p15

Assignment of the polymorphic intestinal mucin gene (MUC2) to chromosome 11p15 SUMMARY A cDNA coding for a mucin expressed in intestine has recently been cloned (Gum et al. 1989). We describe here the use of this cDNA to map the gene (MUC2) to human chromosome 11 using somatic cell hybrids, and to make the regional localization to 11p15 by in situ hybridization. Analysis of the CEPH (Centre 'Étude du Polymorphisme Humain) families revealed that MUC2 forms part of the tight linkage group on llpl5 which contains HRAS, INS, TH and HBBC. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

Assignment of the polymorphic intestinal mucin gene (MUC2) to chromosome 11p15

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References (31)

Publisher
Wiley
Copyright
Copyright © 1990 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1111/j.1469-1809.1990.tb00383.x
Publisher site
See Article on Publisher Site

Abstract

SUMMARY A cDNA coding for a mucin expressed in intestine has recently been cloned (Gum et al. 1989). We describe here the use of this cDNA to map the gene (MUC2) to human chromosome 11 using somatic cell hybrids, and to make the regional localization to 11p15 by in situ hybridization. Analysis of the CEPH (Centre 'Étude du Polymorphisme Humain) families revealed that MUC2 forms part of the tight linkage group on llpl5 which contains HRAS, INS, TH and HBBC.

Journal

Annals of Human GeneticsWiley

Published: Oct 1, 1990

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