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Aortic 4D flow: Quantification of signal‐to‐noise ratio as a function of field strength and contrast enhancement for 1.5T, 3T, and 7T

Aortic 4D flow: Quantification of signal‐to‐noise ratio as a function of field strength and... Purpose To investigate for the first time the feasibility of aortic four‐dimensional (4D) flow at 7T, both contrast enhanced (CE) and non‐CE. To quantify the signal‐to‐noise ratio (SNR) in aortic 4D flow as a function of field strength and CE with gadobenate dimeglumine (MultiHance). Methods Six healthy male volunteers were scanned at 1.5T, 3T, and 7T with both non‐CE and CE acquisitions. Temporal SNR was calculated. Flip angle optimization for CE 4D flow was carried out using Bloch simulations that were validated against in vivo measurements. Results The 7T provided 2.2 times the SNR of 3T while 3T provided 1.7 times the SNR of 1.5T in non‐CE acquisitions in the descending aorta. The SNR gains achieved by CE were 1.8‐fold at 1.5T, 1.7‐fold at 3T, and 1.4‐fold at 7T, respectively. Conclusion The 7T provides a new tool to explore aortic 4D flow, yielding higher SNR that can be used to push the boundaries of acceleration and resolution. Field strength and contrast enhancement at all fields provide significant improvements in SNR. Magn Reson Med 73:1864–1871, 2015. © 2014 Wiley Periodicals, Inc. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Magnetic Resonance in Medicine Wiley

Aortic 4D flow: Quantification of signal‐to‐noise ratio as a function of field strength and contrast enhancement for 1.5T, 3T, and 7T

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References (35)

Publisher
Wiley
Copyright
© 2015 Wiley Periodicals, Inc.
ISSN
0740-3194
eISSN
1522-2594
DOI
10.1002/mrm.25317
pmid
24934930
Publisher site
See Article on Publisher Site

Abstract

Purpose To investigate for the first time the feasibility of aortic four‐dimensional (4D) flow at 7T, both contrast enhanced (CE) and non‐CE. To quantify the signal‐to‐noise ratio (SNR) in aortic 4D flow as a function of field strength and CE with gadobenate dimeglumine (MultiHance). Methods Six healthy male volunteers were scanned at 1.5T, 3T, and 7T with both non‐CE and CE acquisitions. Temporal SNR was calculated. Flip angle optimization for CE 4D flow was carried out using Bloch simulations that were validated against in vivo measurements. Results The 7T provided 2.2 times the SNR of 3T while 3T provided 1.7 times the SNR of 1.5T in non‐CE acquisitions in the descending aorta. The SNR gains achieved by CE were 1.8‐fold at 1.5T, 1.7‐fold at 3T, and 1.4‐fold at 7T, respectively. Conclusion The 7T provides a new tool to explore aortic 4D flow, yielding higher SNR that can be used to push the boundaries of acceleration and resolution. Field strength and contrast enhancement at all fields provide significant improvements in SNR. Magn Reson Med 73:1864–1871, 2015. © 2014 Wiley Periodicals, Inc.

Journal

Magnetic Resonance in MedicineWiley

Published: May 1, 2015

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