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An improved method for the synthesis of optically active tomoxetines and fluoxetines

An improved method for the synthesis of optically active tomoxetines and fluoxetines A chemoenzymatic approach was applied to the preparation of chiral 3‐hydroxy‐3‐arylpropionates and 3‐hydroxy‐4,4,4‐trifluorobutanoate that are potential precursors for certain chiral pharmaceuticals including chiral tomoxetines and fluoxetines. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chinese Journal of Chemistry Wiley

An improved method for the synthesis of optically active tomoxetines and fluoxetines

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References (62)

Publisher
Wiley
Copyright
Copyright © 2004 Wiley Subscription Services, Inc., A Wiley Company
ISSN
1001-604X
eISSN
1614-7065
DOI
10.1002/cjoc.20040220802
Publisher site
See Article on Publisher Site

Abstract

A chemoenzymatic approach was applied to the preparation of chiral 3‐hydroxy‐3‐arylpropionates and 3‐hydroxy‐4,4,4‐trifluorobutanoate that are potential precursors for certain chiral pharmaceuticals including chiral tomoxetines and fluoxetines.

Journal

Chinese Journal of ChemistryWiley

Published: Aug 1, 2004

Keywords: ; ; ;

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