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Ageing and Dementia in a Longitudinal Study of a Cohort with Down Syndrome

Ageing and Dementia in a Longitudinal Study of a Cohort with Down Syndrome Background A population sample of people with Down syndrome has been studied from infancy and has now been followed up again at age 47 years. Methods Intelligence and language skills were tested and daily living skills assessed. Memory/cognitive deterioration was examined using two test instruments. Results Scores on verbal tests of intelligence changed little. Those on a non‐verbal test, on self‐help skills and on both memory tests showed some decline, even when the scores of those already suffering from dementia were discounted. Conclusions At age 47, scores on most tests of even the majority of the cohort (i.e. those not definitely diagnosed with dementia) showed some decline. While this includes the scores of people who may subsequently develop dementia, it may also reflect the normal ageing process in this population. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Research in Intellectual Disabilities Wiley

Ageing and Dementia in a Longitudinal Study of a Cohort with Down Syndrome

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References (49)

Publisher
Wiley
Copyright
Copyright © 2014 John Wiley & Sons Ltd
ISSN
1360-2322
eISSN
1468-3148
DOI
10.1111/jar.12093
pmid
24687962
Publisher site
See Article on Publisher Site

Abstract

Background A population sample of people with Down syndrome has been studied from infancy and has now been followed up again at age 47 years. Methods Intelligence and language skills were tested and daily living skills assessed. Memory/cognitive deterioration was examined using two test instruments. Results Scores on verbal tests of intelligence changed little. Those on a non‐verbal test, on self‐help skills and on both memory tests showed some decline, even when the scores of those already suffering from dementia were discounted. Conclusions At age 47, scores on most tests of even the majority of the cohort (i.e. those not definitely diagnosed with dementia) showed some decline. While this includes the scores of people who may subsequently develop dementia, it may also reflect the normal ageing process in this population.

Journal

Journal of Applied Research in Intellectual DisabilitiesWiley

Published: Jan 1, 2014

Keywords: ; ;

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