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Introduction Quantitative angiography has been used to validate the accuracy of the measurement obtained with the early intravascular ultrasound cathet e r ~ . ' -In more recent reports'-'* it was sug~ gested that intravascular ultrasound can be superior to quantitative angiography in the assessment of complex lesions (eccentric stenoses, asymmetric lesions, vascular dissections). In this article, advantages and limitations of the two techniques in the assessment of vascular dimensions are discussed based on the results reported in the literature and of our experience in 94 patients with coronary artery disease. Previous Studies Comparing Intravascular Ultrasound and Angiography for the Assessment of Vascular Dimensions The results of I I clinical studies in which quantitative angiography and intravascular ultrasound were compared are summarized in Table 1. Differences in equipment and methods of analysis limit the comparison and interpretation of data. Address for reprints: Dr. Patrick W. Serruys, Thoraxcenter. Erasmus University. Room Ee 2332. Dr Molewaterplein 40. 3015 GD Rotterdam. The Netherlands. Fax: 31 10 4633096. Linear regression analysis is most commonly used as a statistical test in these studies. However, a regression coefficient close to I is not sufficient to conclude that the two techniques provide similar quantitative measurements.
Journal of Interventional Cardiology – Wiley
Published: Feb 1, 1994
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