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M. Mikkelsen (1967)
Down's syndrome at young maternal age: cytogenetical and genealogical study of eighty‐one familiesAnnals of Human Genetics, 31
M. Mikkelsen, H. Poulsen, JßRGEN Grinsted, Aksel Lange (1980)
Non‐disjunction in trisomy 21: study of chromosomal heteromorphisms in 110 familiesAnnals of Human Genetics, 44
T. Baker (1963)
A quantitative and cytological study of germ cells in human ovariesProceedings of the Royal Society of London. Series B. Biological Sciences, 158
(1966)
Doum’s Anomaly
J. Mattéi, S. Aymé, M. Mattei, F. Giraud (1980)
Maternal age and origin of non-disjunction in trisomy 21.Journal of Medical Genetics, 17
Papp Papp, Váradi Váradi, Szabó Szabó (1977)
Grandmaternal age at birth of parents of children with trisomy 21hum genet., 39
(1964)
Dermatoglyphs in mosaic mongolism and allied conditions
Summary The age distribution of maternal grandmothers of children with Down syndrome was compared with paternal grandparents of the same group and with grandparents of healthy children (controls). The significant advanced maternal grandmaternal age was found in cases of Down syndrome caused by first meiotic error in the maternal oogenesis. The advanced maternal grandmaternal age was found independent of maternal age. No differences were found between the ages of grandfathers of Down syndrome and of controls.
Annals of Human Genetics – Wiley
Published: Oct 1, 1984
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