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Activated nitriles in heterocyclic synthesis: Facile synthesis of heteroarylthymine analogs and their nucleosides

Activated nitriles in heterocyclic synthesis: Facile synthesis of heteroarylthymine analogs and... 5‐Heteroarylthymine analogs (5) were synthesized via binucleophilic attack with bidentate thiols on the cyano group of cyanoacetylurea to form the heteroarylurea derivatives (2–4) followed by their cyclization with formamide. Also, their nucleosides 6a and 6b with 2,3,4,6‐tetra‐O‐acetyl‐α‐D‐glucopyranose were prepared. © 2000 John Wiley & Sons, Inc. Heteroatom Chem 11:209–212, 2000 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Heteroatom Chemistry Wiley

Activated nitriles in heterocyclic synthesis: Facile synthesis of heteroarylthymine analogs and their nucleosides

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References (7)

Publisher
Wiley
Copyright
Copyright © 2000 John Wiley & Sons, Inc.
ISSN
1042-7163
eISSN
1098-1071
DOI
10.1002/(SICI)1098-1071(2000)11:3<209::AID-HC8>3.0.CO;2-Y
Publisher site
See Article on Publisher Site

Abstract

5‐Heteroarylthymine analogs (5) were synthesized via binucleophilic attack with bidentate thiols on the cyano group of cyanoacetylurea to form the heteroarylurea derivatives (2–4) followed by their cyclization with formamide. Also, their nucleosides 6a and 6b with 2,3,4,6‐tetra‐O‐acetyl‐α‐D‐glucopyranose were prepared. © 2000 John Wiley & Sons, Inc. Heteroatom Chem 11:209–212, 2000

Journal

Heteroatom ChemistryWiley

Published: Jan 1, 2000

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