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A three‐plane architectonic atlas of the rat hippocampal region

A three‐plane architectonic atlas of the rat hippocampal region ABSTRACT The hippocampal region, comprising the hippocampal formation and the parahippocampal region, has been one of the most intensively studied parts of the brain for decades. Better understanding of its functional diversity and complexity has led to an increased demand for specificity in experimental procedures and manipulations. In view of the complex 3D structure of the hippocampal region, precisely positioned experimental approaches require a fine‐grained architectural description that is available and readable to experimentalists lacking detailed anatomical experience. In this paper, we provide the first cyto‐ and chemoarchitectural description of the hippocampal formation and parahippocampal region in the rat at high resolution and in the three standard sectional planes: coronal, horizontal and sagittal. The atlas uses a series of adjacent sections stained for neurons and for a number of chemical marker substances, particularly parvalbumin and calbindin. All the borders defined in one plane have been cross‐checked against their counterparts in the other two planes. The entire dataset will be made available as a web‐based interactive application through the Rodent Brain WorkBench (http://www.rbwb.org) which, together with this paper, provides a unique atlas resource. © 2014 Wiley Periodicals, Inc. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Hippocampus Wiley

A three‐plane architectonic atlas of the rat hippocampal region

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References (125)

Publisher
Wiley
Copyright
© 2015 Wiley Periodicals, Inc.
ISSN
1050-9631
eISSN
1098-1063
DOI
10.1002/hipo.22407
pmid
25533645
Publisher site
See Article on Publisher Site

Abstract

ABSTRACT The hippocampal region, comprising the hippocampal formation and the parahippocampal region, has been one of the most intensively studied parts of the brain for decades. Better understanding of its functional diversity and complexity has led to an increased demand for specificity in experimental procedures and manipulations. In view of the complex 3D structure of the hippocampal region, precisely positioned experimental approaches require a fine‐grained architectural description that is available and readable to experimentalists lacking detailed anatomical experience. In this paper, we provide the first cyto‐ and chemoarchitectural description of the hippocampal formation and parahippocampal region in the rat at high resolution and in the three standard sectional planes: coronal, horizontal and sagittal. The atlas uses a series of adjacent sections stained for neurons and for a number of chemical marker substances, particularly parvalbumin and calbindin. All the borders defined in one plane have been cross‐checked against their counterparts in the other two planes. The entire dataset will be made available as a web‐based interactive application through the Rodent Brain WorkBench (http://www.rbwb.org) which, together with this paper, provides a unique atlas resource. © 2014 Wiley Periodicals, Inc.

Journal

HippocampusWiley

Published: Jul 1, 2015

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