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A theory of the association (overlap) of chromosomes in karyotypes, illustrated by Dr Patricia Jacobs' data

A theory of the association (overlap) of chromosomes in karyotypes, illustrated by Dr Patricia... A theory of the association (overlap) of chromosomes in karyotypes, illustrated by Dr Patricia Jacobs’ data BY J. 0. IRWIN* London School of Hygiene, Keppell Street, London, W.C. 1 1. When a karyotype is observed it may happen that two or more chromosomes ‘overlap’ or are so close together as to be considered ‘associated’. Fig. 1. Tho upper part of the figure shows four chromosomes i association,two members of group n 13-15 and two members of group 21-22, while the lower shows an association of three chromosomes, one member of group 13-15 and two members of group 21-22. As an illustration, Fig. 1, a photograph kindly supplied by Dr P. Jacobs, shows part of a cell from the blood culture of a male mongol. Two groups of associations are well shown. The upper part of the photograph shows four chromosomes in association, two members of group 13-15 on the Denver scale (here called D) and two members of group 21-22 (here called A), while the lower shows an association of three chromosomes, one member of group 13-15 and two members of group 21-22. Suppose that there are n chromosomes moving randomly in the field of observation, that the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

A theory of the association (overlap) of chromosomes in karyotypes, illustrated by Dr Patricia Jacobs' data

Irwin, J. O.
Annals of Human Genetics , Volume 28 (4) – May 1, 1965
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Publisher
Wiley
Copyright
Copyright © 1965 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1111/j.1469-1809.1965.tb00491.x
Publisher site
See Article on Publisher Site

Abstract

A theory of the association (overlap) of chromosomes in karyotypes, illustrated by Dr Patricia Jacobs’ data BY J. 0. IRWIN* London School of Hygiene, Keppell Street, London, W.C. 1 1. When a karyotype is observed it may happen that two or more chromosomes ‘overlap’ or are so close together as to be considered ‘associated’. Fig. 1. Tho upper part of the figure shows four chromosomes i association,two members of group n 13-15 and two members of group 21-22, while the lower shows an association of three chromosomes, one member of group 13-15 and two members of group 21-22. As an illustration, Fig. 1, a photograph kindly supplied by Dr P. Jacobs, shows part of a cell from the blood culture of a male mongol. Two groups of associations are well shown. The upper part of the photograph shows four chromosomes in association, two members of group 13-15 on the Denver scale (here called D) and two members of group 21-22 (here called A), while the lower shows an association of three chromosomes, one member of group 13-15 and two members of group 21-22. Suppose that there are n chromosomes moving randomly in the field of observation, that the

Journal

Annals of Human Genetics – Wiley

Published: May 1, 1965

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