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A State‐of‐the‐Art Review of Laser‐Assisted Bioprinting and its Future Research Trends

A State‐of‐the‐Art Review of Laser‐Assisted Bioprinting and its Future Research Trends Bioprinting is an additive manufacturing technology with great potential in medical applications. Among available bioprinting techniques, laser‐assisted bioprinting (LAB) is a promising technique due to its high resolution, high cell viability, and the capability to deposit high‐viscousity bioink. These characteristics allow the LAB technology to control cells precisely to reconstruct living organs. Recent developments of LAB technologies are reviewed in this paper, covering various designs of LAB printers, research progresses in energy‐absorbing layer (EAL), the physical phenomenon that triggers the printing process in terms of bubble formation and jet development, printing process parameters, and major factors related to the post‐printing cell viability. The latest studies on LAB technologies are highlighted, expounding their advantages and disadvantages, and some potential applications are presented. The potential technical challenges and future research trends for LAB technologies are also discussed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chembioeng Reviews Wiley

A State‐of‐the‐Art Review of Laser‐Assisted Bioprinting and its Future Research Trends

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References (127)

Publisher
Wiley
Copyright
© 2021 Wiley‐VCH GmbH
eISSN
2196-9744
DOI
10.1002/cben.202000037
Publisher site
See Article on Publisher Site

Abstract

Bioprinting is an additive manufacturing technology with great potential in medical applications. Among available bioprinting techniques, laser‐assisted bioprinting (LAB) is a promising technique due to its high resolution, high cell viability, and the capability to deposit high‐viscousity bioink. These characteristics allow the LAB technology to control cells precisely to reconstruct living organs. Recent developments of LAB technologies are reviewed in this paper, covering various designs of LAB printers, research progresses in energy‐absorbing layer (EAL), the physical phenomenon that triggers the printing process in terms of bubble formation and jet development, printing process parameters, and major factors related to the post‐printing cell viability. The latest studies on LAB technologies are highlighted, expounding their advantages and disadvantages, and some potential applications are presented. The potential technical challenges and future research trends for LAB technologies are also discussed.

Journal

Chembioeng ReviewsWiley

Published: Oct 1, 2021

Keywords: Additive manufacturing; Bioprinting; Laser‐assisted bioprinting; Laser‐induced forward transfer; Regenerative medicine

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