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J. Luche, C. Pétrier, A. Gemal, N. Zikra (1982)
Ultrasound in organic synthesis. 2. Formation and reaction of organocopper reagentsJournal of Organic Chemistry, 47
Chun‐An Fan, B. Wang, Y. Tu, Zhenlei Song (2001)
Samarium-Catalyzed Tandem Semipinacol Rearrangement/Tishchenko Reaction of α-Hydroxy Epoxides: A Novel Approach to Highly Stereoselective Construction of 2-Quaternary 1,3-Diol Units.Angewandte Chemie, 40 20
C. McComas, J. Perales, D. Vranken (2002)
Synthesis of (+/-)-madindolines and chemical models. Studies of chemical reactivity.Organic letters, 4 14
T. Sunazuka, T. Hirose, T. Shirahata, Y. Harigaya, M. Hayashi, and Komiyama, S. Ōmura, Iii Smith (2000)
Total Synthesis of (+)-Madindoline A and (−)-Madindoline B, Potent, Selective Inhibitors of Interleukin 6. Determination of the Relative and Absolute ConfigurationsJournal of the American Chemical Society, 122
S. Takamatsu, Y. Kim, A. Enomoto, M. Hayashi, H. Tanaka, K. Komiyama, S. Ōmura (1997)
Madindolines, novel inhibitors of IL-6 activity from streptomyces sp. K93-0711. II. Physico-chemical properties and structural elucidation.The Journal of antibiotics, 50 12
Y. Tu, A. Sun, Pingzhen Wang (1999)
Stereoselective Reductive Rearrangement of α-Hydroxy Epoxides: A New Method for Synthesis of 1,3-Diols1Journal of Organic Chemistry, 64
S. Hosokawa, Kazuhiko Sekiguchi, Manabu Enemoto, Susumu Kobayashi (2000)
Novel stereoselective construction of a quaternary carbon: application to synthesis of the cyclopentenedione moiety of madindolinesTetrahedron Letters, 41
M. Arnó, Miguel González, R. Zaragozá (1999)
Diastereoselective synthesis of spongian diterpenes. Total synthesis of the furanoditerpene (−)-spongia-13(16),14-dieneTetrahedron, 55
E. Corey (1953)
The Stereochemistry of α-Haloketones. I. The Molecular Configurations of Some Monocyclic α-HalocyclanonesJournal of the American Chemical Society, 75
D. Li, W. Xia, Y. Tu, Fu‐Min Zhang, Lei Shi (2003)
A novel AlEt3-promoted tandem reductive rearrangement of 1-benzyloxy-2,3-epoxides: new route to 2-quaternary 1,3-diol units.Chemical communications, 6
Y. Ito*, T. Hirao, T. Saegusa (1978)
Synthesis of .alpha.,.beta.-unsaturated carbonyl compounds by palladium(II)-catalyzed dehydrosilylation of silyl enol ethersJournal of Organic Chemistry, 43
T. Hirose, T. Sunazuka, T. Shirahata, D. Yamamoto, Y. Harigaya, I. Kuwajima, S. Ōmura (2002)
Short total synthesis of (+)-madindolines A and B.Organic letters, 4 4
R. Holysz (1953)
Preparation and Dehydrohalogenation of 4-Halo-3-ketosteroidsJournal of the American Chemical Society, 75
S. Ōmura, Msasahiko Hayashi, H. Tomoda (1999)
Recent progress of the research on novel microbial metabolitesPure and Applied Chemistry, 71
J. Luche (1978)
Lanthanides in organic chemistry. 1. Selective 1,2 reductions of conjugated ketonesJournal of the American Chemical Society, 100
S. Hosokawa, Susumu Kobayashi (2000)
Total Synthesis of Madindoline AJournal of Synthetic Organic Chemistry Japan, 59
M. Hayashi, Y. Kim, S. Takamatsu, A. Enomoto, M. Shinose, Y. Takahashi, H. Tanaka, K. Komiyama, S. Ōmura (1996)
Madindoline, a novel inhibitor of IL-6 activity from Streptomyces sp. K93-0711. I. Taxonomy, fermentation, isolation and biological activities.The Journal of antibiotics, 49 11
The fully substituted cyclopentenedione core of madindoline A (1) and B (2) as potent and selective inhibitor of IL‐6 has been synthesized efficiently. The quaternary carbon center C‐2′ was constructed on the basis of a newly developed AlEt3‐promoted tandem reductive rearrangement of α‐hydroxy epoxides.
Chinese Journal of Chemistry – Wiley
Published: May 1, 2006
Keywords: ; ; ; ;
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