Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

A Novel Strategy for the Key Fully Substituted Cyclopentenedione Moiety of Madindolines via AlEt3‐promoted Tandem Reductive Rearrangement of α‐Hydroxy Epoxides

A Novel Strategy for the Key Fully Substituted Cyclopentenedione Moiety of Madindolines via... The fully substituted cyclopentenedione core of madindoline A (1) and B (2) as potent and selective inhibitor of IL‐6 has been synthesized efficiently. The quaternary carbon center C‐2′ was constructed on the basis of a newly developed AlEt3‐promoted tandem reductive rearrangement of α‐hydroxy epoxides. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chinese Journal of Chemistry Wiley

A Novel Strategy for the Key Fully Substituted Cyclopentenedione Moiety of Madindolines via AlEt3‐promoted Tandem Reductive Rearrangement of α‐Hydroxy Epoxides

Loading next page...
 
/lp/wiley/a-novel-strategy-for-the-key-fully-substituted-cyclopentenedione-hZFaRsv1Jn

References (17)

Publisher
Wiley
Copyright
Copyright © 2006 Wiley Subscription Services, Inc., A Wiley Company
ISSN
1001-604X
eISSN
1614-7065
DOI
10.1002/cjoc.200690114
Publisher site
See Article on Publisher Site

Abstract

The fully substituted cyclopentenedione core of madindoline A (1) and B (2) as potent and selective inhibitor of IL‐6 has been synthesized efficiently. The quaternary carbon center C‐2′ was constructed on the basis of a newly developed AlEt3‐promoted tandem reductive rearrangement of α‐hydroxy epoxides.

Journal

Chinese Journal of ChemistryWiley

Published: May 1, 2006

Keywords: ; ; ; ;

There are no references for this article.