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A new model for measuring breeding genetic distance: II. Polygenic traits

A new model for measuring breeding genetic distance: II. Polygenic traits Summary The breeding genetic distance measure of a single locus (Carlson & Welch, 1977) is extended to polygenic traits. For two populations with means 5 and 2,8(5,2) is defined as thesize of thelargest subpopulation with mean 2 which can be (artificially) selected from a population with mean F. The distance is defined as 1 ‐ O(5, Z). It is shown that 8(X, 2) can be calculated from truncation selection and formulas (two loci) and tables (three and four loci) are given. Values for 8(5,2) based on a normal approximation are seen to be adequate for most cases. The measure is applied to a data example (human skin colour) and to a discussion of the idea of 'genetic inertia'. This research was supported in part by the Child Health and Development Studies, School of Public Health, University of California, Berkeley, CA 94720, NICHHD Grant HD 07256. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

A new model for measuring breeding genetic distance: II. Polygenic traits

Annals of Human Genetics , Volume 41 (4) – May 1, 1978

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References (6)

Publisher
Wiley
Copyright
Copyright © 1978 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1111/j.1469-1809.1978.tb00921.x
Publisher site
See Article on Publisher Site

Abstract

Summary The breeding genetic distance measure of a single locus (Carlson & Welch, 1977) is extended to polygenic traits. For two populations with means 5 and 2,8(5,2) is defined as thesize of thelargest subpopulation with mean 2 which can be (artificially) selected from a population with mean F. The distance is defined as 1 ‐ O(5, Z). It is shown that 8(X, 2) can be calculated from truncation selection and formulas (two loci) and tables (three and four loci) are given. Values for 8(5,2) based on a normal approximation are seen to be adequate for most cases. The measure is applied to a data example (human skin colour) and to a discussion of the idea of 'genetic inertia'. This research was supported in part by the Child Health and Development Studies, School of Public Health, University of California, Berkeley, CA 94720, NICHHD Grant HD 07256.

Journal

Annals of Human GeneticsWiley

Published: May 1, 1978

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