Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

A Multi‐Signaling Performance for Simultaneous Surveillance and Accretion of Cysteine and Serine in Human Cancer Cell

A Multi‐Signaling Performance for Simultaneous Surveillance and Accretion of Cysteine and Serine... A unique fluorescence chemosensing method has been introduced to explain a new strategy for simultaneous selective determination of cysteine and serine in two different emission channels through an “on‐off‐on” mechanism. Dansyl chloride‐picolylamine conjugate (DNPC) ensembles with Cu2+ (DNPC‐Cu2+) and shows a turn‐on fluorescence while binding with serine or cysteine. Fluorescence, NMR titrations and DFT calculations has been performed in order to understand the sensing mechanism and the electronic properties of the receptor‐donor complex. The chemosensing method has been successfully applied in human cancer cells to detect and quantify cysteine and serine differentially. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Asian Journal of Organic Chemistry Wiley

A Multi‐Signaling Performance for Simultaneous Surveillance and Accretion of Cysteine and Serine in Human Cancer Cell

Loading next page...
 
/lp/wiley/a-multi-signaling-performance-for-simultaneous-surveillance-and-pbSP4L43eI

References (50)

Publisher
Wiley
Copyright
© 2020 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim
ISSN
2193-5807
eISSN
2193-5815
DOI
10.1002/ajoc.201900642
Publisher site
See Article on Publisher Site

Abstract

A unique fluorescence chemosensing method has been introduced to explain a new strategy for simultaneous selective determination of cysteine and serine in two different emission channels through an “on‐off‐on” mechanism. Dansyl chloride‐picolylamine conjugate (DNPC) ensembles with Cu2+ (DNPC‐Cu2+) and shows a turn‐on fluorescence while binding with serine or cysteine. Fluorescence, NMR titrations and DFT calculations has been performed in order to understand the sensing mechanism and the electronic properties of the receptor‐donor complex. The chemosensing method has been successfully applied in human cancer cells to detect and quantify cysteine and serine differentially.

Journal

Asian Journal of Organic ChemistryWiley

Published: Jan 1, 2020

Keywords: ; ; ;

There are no references for this article.