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A mild and efficient synthesis of intermediates for the Pomeranz‐Fritsch reaction

A mild and efficient synthesis of intermediates for the Pomeranz‐Fritsch reaction Reaction of 1‐chloro‐2,2‐dimethoxyethane with sodium azide affords 1‐azido‐2,2‐dimethoxyethane which, upon treatment with triphenylphosphine followed by aromatic aldehydes, alkyl bromides, or isocyanates, gives the corresponding dimethyl α‐arylimino‐, α‐alkylamino‐, and α‐carbodiimido‐acetals, respectively, in good to excellent yields. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Heteroatom Chemistry Wiley

A mild and efficient synthesis of intermediates for the Pomeranz‐Fritsch reaction

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References (7)

Publisher
Wiley
Copyright
Copyright © 1994 Wiley Subscription Services
ISSN
1042-7163
eISSN
1098-1071
DOI
10.1002/hc.520050204
Publisher site
See Article on Publisher Site

Abstract

Reaction of 1‐chloro‐2,2‐dimethoxyethane with sodium azide affords 1‐azido‐2,2‐dimethoxyethane which, upon treatment with triphenylphosphine followed by aromatic aldehydes, alkyl bromides, or isocyanates, gives the corresponding dimethyl α‐arylimino‐, α‐alkylamino‐, and α‐carbodiimido‐acetals, respectively, in good to excellent yields.

Journal

Heteroatom ChemistryWiley

Published: Jan 1, 1994

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