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H. Gock, L. Murray-Segal, E. Salvaris, N. Fisicaro, P. Cowan, A. D'apice (2006)
Cardiac and Skin Xenograft Survival in Different Recipient Mouse StrainsTransplantation, 82
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Blockade of Extracellular HMGB1 Suppresses Xenoreactive B Cell Responses and Delays Acute Vascular Xenogeneic RejectionAmerican Journal of Transplantation, 15
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CD4 T cells mediate cardiac xenograft rejection via host MHC Class II.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 31 9
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Father” of experimental microsurgery
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Attenuation of acute xenograft rejection by short-term treatment with LF15-0195 and monoclonal antibody against CD45RB in a rat-to-mouse cardiac transplantation model1Transplantation, 75
Hao Wang, J. Arp, Xuyan Huang, Weihua Liu, S. Ramcharran, Jifu Jiang, B. Garcia, N. Kanai, W. Min, P. O’Connell, R. Zhong (2006)
Distinct Subsets of Dendritic Cells Regulate the Pattern of Acute Xenograft Rejection and Susceptibility to Cyclosporine Therapy1The Journal of Immunology, 176
松浦 昭雄 (1993)
Simplified mouse cervical heart transplantation using a cuff technique
Matsuura (1991)
Simplified mouse cervical heart transplantation using a cuff techniqueTransplantation, 51
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CD80/CD86 Costimulation Regulates Acute Vascular Rejection1The Journal of Immunology, 175
Xenotransplantation is an effective way to solve the problem of donor shortage in clinical transplantation. However, clinical use of xenotransplantation is currently limited due to immunological challenges such as acute vascular rejection and cell‐mediated rejection. To finally surpass this immunological barrier, more preclinical research is needed into the molecular mechanisms of rejection and the possible effects of new immunosuppressants. Our aim was to create a refined, highly reproducible protocol to establish the most suitable rat‐to‐mouse heterotopic heart transplantation model using the cuff technique.
Xenotransplantation – Wiley
Published: Jan 1, 2017
Keywords: ; ; ; ;
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