Access the full text.
Sign up today, get DeepDyve free for 14 days.
(2019)
Biofabrication 2010 , 2 , 035003;
Zhuang Pei, Y. Chiang, Maria Fernanda, M. He (2021)
Using Spheroids as Building Blocks Towards 3D Bioprinting of Tumor MicroenvironmentInternational Journal of Bioprinting, 7
Sarah Chaji, Jenna Al-Saleh, C. Gomillion (2020)
Bioprinted Three-Dimensional Cell-Laden Hydrogels to Evaluate Adipocyte-Breast Cancer Cell InteractionsGels, 6
S. Firth, R. Baxter (2002)
Cellular actions of the insulin-like growth factor binding proteins.Endocrine reviews, 23 6
M. Dvir-Ginzberg, Tsiona Elkayam, Smadar Cohen (2008)
Induced differentiation and maturation of newborn liver cells into functional hepatic tissue in macroporous alginate scaffoldsThe FASEB Journal, 22
(2023)
The Authors. Advanced Functional Materials published by Wiley-VCH GmbH www.advancedsciencenews.com www.afm-journal.de
S. Siboro, D. Anugrah, Kalyan Ramesh, Sang-Hyug Park, Hyeung‐Rak Kim, K. Lim (2021)
Tunable porosity of covalently crosslinked alginate-based hydrogels and its significance in drug release behavior.Carbohydrate polymers, 260
R. Xue, M. Lynes, J. Dreyfuss, Farnaz Shamsi, T. Schulz, Hongbin Zhang, Tian Huang, K. Townsend, Yiming Li, Hirokazu Takahashi, Lauren Weiner, Andrew White, Maureen Lynes, L. Rubin, L. Goodyear, A. Cypess, Y. Tseng (2015)
Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytesNature Medicine, 21
M. Chi, J. Chen, Y. Ye, Hsin-Yi Tseng, F. Lai, K. Tay, L. Jin, S. Guo, C. Jiang, X. Zhang (2014)
Adipocytes contribute to resistance of human melanoma cells to chemotherapy and targeted therapy.Current medicinal chemistry, 21 10
R. Hynes (2014)
Stretching the boundaries of extracellular matrix researchNature Reviews Molecular Cell Biology, 15
Wilhelm Palm, C. Thompson (2017)
Nutrient acquisition strategies of mammalian cellsNature, 546
(2003)
Gels 2020, 6, 10; c)
Milim Kim, Hye Choi, J. Woo, Yul Chung, S. Park (2021)
Role of CXCL10 in the progression of in situ to invasive carcinoma of the breastScientific Reports, 11
J. Dumas, L. Brisson (2020)
Interaction between adipose tissue and cancer cells: role for cancer progressionCancer and Metastasis Reviews, 40
(2012)
Drug Delivery Rev
Wen Xue, Seok-Yeong Yu, Mitchell Kuss, Yunfan Kong, Wen Shi, Soonkyu Chung, So-Youn Kim, B. Duan (2022)
3D bioprinted white adipose model for in vitro study of cancer-associated cachexia induced adipose tissue remodelingBiofabrication, 14
Kevin France, Fei Xu, T. Hoare (2018)
Structured Macroporous Hydrogels: Progress, Challenges, and OpportunitiesAdvanced Healthcare Materials, 7
Donghee Lee, Sydney Greer, Mitchell Kuss, Yang An, A. Dudley (2021)
3D printed alginate bead generator for high-throughput cell cultureBiomedical Microdevices, 23
Therese Andersen, Pia Auk-Emblem, M. Dornish (2015)
3D Cell Culture in Alginate HydrogelsMicroarrays, 4
A. Sergeeva, A. Vikulina, D. Volodkin (2019)
Porous Alginate Scaffolds Assembled Using Vaterite CaCO3 CrystalsMicromachines, 10
Seher Balaban, Robert Shearer, Lisa Lee, M. Geldermalsen, Mark Schreuder, Harrison Shtein, Rose Cairns, Kristen Thomas, D. Fazakerley, T. Grewal, J. Holst, D. Saunders, A. Hoy (2017)
Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migrationCancer & Metabolism, 5
S. Partap, I. Rehman, Julian Jones, J. Darr (2006)
“Supercritical Carbon Dioxide in Water” Emulsion‐Templated Synthesis of Porous Calcium Alginate HydrogelsAdvanced Materials, 18
K. Kabiri, H. Omidian, M. Zohuriaan‐Mehr (2003)
Novel approach to highly porous superabsorbent hydrogels: synergistic effect of porogens on porosity and swelling ratePolymer International, 52
K. Lee, D. Mooney (2012)
Alginate: properties and biomedical applications.Progress in polymer science, 37 1
A. Barbetta, Elena Barigelli, M. Dentini (2009)
Porous alginate hydrogels: synthetic methods for tailoring the porous texture.Biomacromolecules, 10 8
Jieun Seo, K. Kim, Jong-Wan Park, Joo-Youn Cho, Hak Chang, J. Fukuda, K. Hong, Y. Chun (2020)
Metastasis-on-a-chip reveals adipocyte-derived lipids trigger cancer cell migration via HIF-1α activation in cancer cells.Biomaterials, 269
K. Hossain, U. Patel, I. Ahmed (2014)
Development of microspheres for biomedical applications: a reviewProgress in Biomaterials, 4
Jiyoung Park, Thomas Morley, Min Kim, D. Clegg, P. Scherer (2014)
Obesity and cancer—mechanisms underlying tumour progression and recurrenceNature Reviews Endocrinology, 10
B. Slaughter, S. Khurshid, O. Fisher, A. Khademhosseini, N. Peppas (2009)
Hydrogels in Regenerative MedicineAdvanced Materials, 21
Weizhi Chen, Sensen Zhou, Lei Ge, Wei Wu, Xiqun Jiang (2018)
Translatable High Drug Loading Drug Delivery Systems Based on Biocompatible Polymer Nanocarriers.Biomacromolecules, 19 6
Y. Li, Yasamin Jodat, R. Samanipour, Giulio Zorzi, Kai Zhu, Minoru Hirano, Karen Chang, A. Arnaout, Shabir Hassan, Navneet Matharu, A. Khademhosseini, M. Hoorfar, S. Shin (2020)
Toward a neurospheroid niche model: optimizing embedded 3D bioprinting for fabrication of neurospheroid brain-like co-culture constructsBiofabrication, 13
Endocrinol
(2016)
Stem Cells Int.
Nathaniel Huebsch, E. Lippens, Kangwon Lee, M. Mehta, Sandeep Koshy, Max Darnell, Rajiv Desai, C. Madl, Maria Xu, Xuanhe Zhao, Ovijit Chaudhuri, Catia Verbeke, Woo Kim, K. Alim, A. Mammoto, D. Ingber, G. Duda, D. Mooney (2015)
Matrix Elasticity of Void-Forming Hydrogels Controls Transplanted Stem Cell-Mediated Bone FormationNature materials, 14
N. Annabi, J. Nichol, Xiamei Zhong, Chengdong Ji, Sandeep Koshy, A. Khademhosseini, F. Dehghani (2010)
Controlling the porosity and microarchitecture of hydrogels for tissue engineering.Tissue engineering. Part B, Reviews, 16 4
Hailin Zhao, Qian Chen, Azeem Alam, J. Cui, Ka‐Chun Suen, Aurelie Soo, S. Eguchi, J. Gu, D. Ma (2018)
The role of osteopontin in the progression of solid organ tumourCell Death & Disease, 9
Yang-an Wen, X. Xing, Jennifer Harris, Yekaterina Zaytseva, Mihail Mitov, D. Napier, H. Weiss, B. Evers, Tianyan Gao (2017)
Adipocytes activate mitochondrial fatty acid oxidation and autophagy to promote tumor growth in colon cancerCell Death & Disease, 8
Liran Ma, Anastasia Gaisinskaya-Kipnis, N. Kampf, J. Klein (2015)
Origins of hydration lubricationNature Communications, 6
A. Mondal, Aragaw Gebeyehu, Mariza Miranda, Divya Bahadur, N. Patel, S. Ramakrishnan, A. Rishi, Mandip Singh (2019)
Characterization and printability of Sodium alginate -Gelatin hydrogel for bioprinting NSCLC co-cultureScientific Reports, 9
Lucie Léonard, Adem Gharsallaoui, Fahima Ouaali, P. Degraeve, Y. Waché, R. Saurel, N. Oulahal (2013)
Preferential localization of Lactococcus lactis cells entrapped in a caseinate/alginate phase separated system.Colloids and surfaces. B, Biointerfaces, 109
N. Visavadiya, Gabriel Pena, A. Khamoui (2020)
Mitochondrial dynamics and quality control are altered in a hepatic cell culture model of cancer cachexiaMolecular and Cellular Biochemistry, 476
N. Broguiere, A. Husch, G. Palazzolo, F. Bradke, S. Madduri, M. Zenobi‐Wong (2019)
Macroporous hydrogels derived from aqueous dynamic phase separation.Biomaterials, 200
Zoe Cesarz, K. Tamama (2015)
Spheroid Culture of Mesenchymal Stem CellsStem Cells International, 2016
Dongmei Chen, Shudan Liu, Huiming Ma, Xueyun Liang, Haibin Ma, Xiurui Yan, Bao Yang, Jun Wei, Xiaoming Liu (2015)
Paracrine factors from adipose-mesenchymal stem cells enhance metastatic capacity through Wnt signaling pathway in a colon cancer cell co-culture modelCancer Cell International, 15
R. Kankala, Jia Zhao, Chen-Guang Liu, Xiao-jie Song, Dayun Yang, Kai Zhu, Shi-Bin Wang, Y. Zhang, A. Chen (2019)
Highly Porous Microcarriers for Minimally Invasive In Situ Skeletal Muscle Cell Delivery.Small
Erin Johnson, W. Deen (1996)
Hydraulic permeability of agarose gelsAiche Journal, 42
Haobin Ye, Biniam Adane, Nabilah Khan, T. Sullivan, Mohammad Minhajuddin, M. Gasparetto, Brett Stevens, Shanshan Pei, M. Balys, J. Ashton, D. Klemm, Carolien Woolthuis, Alec Stranahan, Christopher Park, C. Jordan (2016)
Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche.Cell stem cell, 19 1
J. Bruun, S. Pedersen, B. Richelsen (2001)
Regulation of interleukin 8 production and gene expression in human adipose tissue in vitro.The Journal of clinical endocrinology and metabolism, 86 3
Wen Xue, Bo Liu, Haipeng Zhang, S. Ryu, Mitchell Kuss, Devanshi Shukla, Guoku Hu, Shih-Hao Wen, Xiping Jiang, Y. Lei, B. Duan (2021)
Controllable Fabrication of Alginate/poly-L-ornithine Polyelectrolyte Complex Hydrogel Networks as Therapeutic Drug and Cell Carriers.Acta biomaterialia
(2009)
, Biomateri-als
Wen Xue, Yunfan Kong, Rafay Abu, Pooja Roy, S. Huh, Mitchell Kuss, Prof Kumar, B. Duan (2022)
Regulation of Schwann Cell and DRG Neurite Behaviors within Decellularized Peripheral Nerve Matrix.ACS applied materials & interfaces
A. Sergeeva, N. Feoktistova, Vladimir Prokopović, D. Gorin, D. Volodkin (2015)
Design of Porous Alginate Hydrogels by Sacrificial CaCO3 Templates: Pore Formation MechanismAdvanced Materials Interfaces, 2
Nipha Chaicharoenaudomrung, Phongsakorn Kunhorm, Parinya Noisa (2019)
Three-dimensional cell culture systems as an in vitro platform for cancer and stem cell modelingWorld Journal of Stem Cells, 11
Liantao Li, G. Jiang, Qian Chen, Junnian Zheng (2015)
Ki67 is a promising molecular target in the diagnosis of cancer (review).Molecular medicine reports, 11 3
Sonia Partap, A. Muthutantri, I. Rehman, Graham Davis, J. Darr (2007)
Preparation and characterisation of controlled porosity alginate hydrogels made via a simultaneous micelle templating and internal gelation processJournal of Materials Science, 42
C. Hwang, S. Sant, Mahdokht Masaeli, N. Kachouie, B. Zamanian, Sang‐Hoon Lee, A. Khademhosseini (2010)
Fabrication of three-dimensional porous cell-laden hydrogel for tissue engineeringBiofabrication, 2
Hang Zhao, Xiao–kun Ouyang, Li-ye Yang (2021)
Adsorption of lead ions from aqueous solutions by porous cellulose nanofiber–sodium alginate hydrogel beadsJournal of Molecular Liquids, 324
Pei Zhuang, A. Sun, J. An, C. Chua, S. Chew (2018)
3D neural tissue models: From spheroids to bioprinting.Biomaterials, 154
G. Ying, N. Jiang, S. Maharjan, Yixia Yin, Rong‐Rong Chai, Xia Cao, Jingzhou Yang, A. Miri, Shabir Hassan, Y. Zhang (2018)
Aqueous Two‐Phase Emulsion Bioink‐Enabled 3D Bioprinting of Porous HydrogelsAdvanced Materials, 30
K. Nieman, Iris Romero, B. Houten, E. Lengyel (2013)
Adipose tissue and adipocytes support tumorigenesis and metastasis.Biochimica et biophysica acta, 1831 10
A. Subramanian, A. Sharma, K. Mokbel (2007)
Insulin-like growth factor binding proteins and breast cancerBreast Cancer Research and Treatment, 107
E. Lengyel, L. Makowski, J. DiGiovanni, M. Kolonin (2018)
Cancer as a Matter of Fat: The Crosstalk between Adipose Tissue and Tumors.Trends in cancer, 4 5
Tooba Shoaib, Joe Heintz, Josue Lopez-Berganza, R. Muro-Barrios, Simon Egner, R. Espinosa‐Marzal (2017)
Stick-Slip Friction Reveals Hydrogel Lubrication Mechanisms.Langmuir : the ACS journal of surfaces and colloids, 34 3
Shuan Rao, L. Tortola, Thomas Perlot, Gerald Wirnsberger, M. Novatchkova, R. Nitsch, P. Sykacek, Lukas Frank, D. Schramek, Vukoslav Komnenovic, Verena Sigl, Karin Aumayr, Gerald Schmauss, Nicole Fellner, S. Handschuh, M. Glösmann, P. Pasierbek, M. Schlederer, G. Resch, Yuting Ma, H. Yang, H. Popper, L. Kenner, G. Kroemer, J. Penninger (2014)
A dual role for autophagy in a murine model of lung cancerNature Communications, 5
Sébastien Sart, A. Tsai, Yan Li, T. Ma (2014)
Three-dimensional aggregates of mesenchymal stem cells: cellular mechanisms, biological properties, and applications.Tissue engineering. Part B, Reviews, 20 5
M. Tabuso, S. Homer-Vanniasinkam, R. Adya, R. Arasaradnam (2017)
Role of tissue microenvironment resident adipocytes in colon cancerWorld Journal of Gastroenterology, 23
Fabian Preisner, U. Leimer, Stefanie Sandmann, I. Zoernig, G. Germann, E. Koellensperger (2018)
Impact of Human Adipose Tissue-Derived Stem Cells on Malignant Melanoma Cells in An In Vitro Co-culture ModelStem Cell Reviews and Reports, 14
S. Park, Byumseok Koh, W. Jung, Kyoung-Jin Choi, Y. Na, H. Yoo, Sunray Lee, Dukjin Kang, Dong-Mok Lee, K. Kim (2020)
Development of a three‐dimensional in vitro co‐culture model to increase drug selectivity for humansDiabetes, 22
Porous alginate (Alg) hydrogels possess many advantages as cell carriers. However, current pore generation methods require either complex or harsh fabrication processes, toxic components, or extra purification steps, limiting the feasibility and affecting the cellular survival and function. In this study, a simple and cell‐friendly approach to generate highly porous cell‐laden Alg hydrogels based on two‐phase aqueous emulsions is reported. The pre‐gel solutions, which contain two immiscible aqueous phases of Alg and caseinate (Cas), are cross‐linked by calcium ions. The porous structure of the hydrogel construct is formed by subsequently removing the Cas phase from the ion‐cross‐linked Alg hydrogel. Those porous Alg hydrogels possess heterogeneous pores ≈100 µm and interconnected paths. Human white adipose progenitors (WAPs) encapsulated in these hydrogels self‐organize into spheroids and show enhanced viability, proliferation, and adipogenic differentiation, compared to non‐porous constructs. As a proof of concept, this porous Alg hydrogel platform is employed to prepare core‐shell spheres for coculture of WAPs and colon cancer cells, with WAP clusters distributed around cancer cell aggregates, to investigate cellular crosstalk. This efficacious approach is believed to provide a robust and versatile platform for engineering porous‐structured Alg hydrogels for applications as cell carriers and in disease modeling.
Advanced Functional Materials – Wiley
Published: Aug 1, 2023
Keywords: adipose‐cancer interaction; core‐shell; porous hydrogels; spheroids; two‐phase aqueous emulsions
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.