Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

7th Congress of the International Xenotransplantation Association

7th Congress of the International Xenotransplantation Association At the 6th Congress of the International Xenotransplantation Association (IXA) held in Chicago 2001, David Cooper presented a short history of our Association [ 1 ]. Using this as a foundation, I will look to the future and give my views of where xenotransplantation is going. My focus will be on the potential of pig‐to‐human transplantation and will not give due recognition to the excellent science emanating from smaller animal models, which could ultimately improve patient survival. Aims of xenotransplantation It is clear that the enormous success of allotransplantation over the last 40 yr has created a problem in that the demand for organs is greater than the supply. Indeed, only approximately 25% of individuals who require an allograft can receive a kidney, heart or liver transplant and <1% of those requiring a pancreatic islet transplant. The provision of pig organs as xenografts would clearly satisfy this need. As we are progressing, we should consider a second reason why xenotransplantation is required – the slow and steady deterioration in the function of allografts. We should bear this in mind as we have the ability to genetically modify xenograft donors and make ‘human‐acceptable’ organs that will have prolonged survival http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Xenotransplantation Wiley

7th Congress of the International Xenotransplantation Association

Xenotransplantation , Volume 11 (3) – May 1, 2004

Loading next page...
 
/lp/wiley/7th-congress-of-the-international-xenotransplantation-association-NNDg41ZAAH

References (11)

Publisher
Wiley
Copyright
Copyright © 2004 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0908-665X
eISSN
1399-3089
DOI
10.1111/j.1399-3089.2004.00120.x
pmid
15099201
Publisher site
See Article on Publisher Site

Abstract

At the 6th Congress of the International Xenotransplantation Association (IXA) held in Chicago 2001, David Cooper presented a short history of our Association [ 1 ]. Using this as a foundation, I will look to the future and give my views of where xenotransplantation is going. My focus will be on the potential of pig‐to‐human transplantation and will not give due recognition to the excellent science emanating from smaller animal models, which could ultimately improve patient survival. Aims of xenotransplantation It is clear that the enormous success of allotransplantation over the last 40 yr has created a problem in that the demand for organs is greater than the supply. Indeed, only approximately 25% of individuals who require an allograft can receive a kidney, heart or liver transplant and <1% of those requiring a pancreatic islet transplant. The provision of pig organs as xenografts would clearly satisfy this need. As we are progressing, we should consider a second reason why xenotransplantation is required – the slow and steady deterioration in the function of allografts. We should bear this in mind as we have the ability to genetically modify xenograft donors and make ‘human‐acceptable’ organs that will have prolonged survival

Journal

XenotransplantationWiley

Published: May 1, 2004

There are no references for this article.