Access the full text.
Sign up today, get DeepDyve free for 14 days.
B. Nannenga, Dan Shi, A. Leslie, T. Gonen (2014)
High-resolution structure determination by continuous rotation data collection in MicroEDNature methods, 11
I. Nederlof, E. Genderen, Yao-Wang Li, J. Abrahams (2013)
A Medipix quantum area detector allows rotation electron diffraction data collection from submicrometre three-dimensional protein crystalsActa Crystallographica Section D: Biological Crystallography, 69
Mark Feyand, E. Mugnaioli, F. Vermoortele, B. Bueken, Johannes Dieterich, T. Reimer, U. Kolb, D. Vos, N. Stock (2012)
Automated diffraction tomography for the structure elucidation of twinned, sub-micrometer crystals of a highly porous, catalytically active bismuth metal-organic framework.Angewandte Chemie, 51 41
A. Lanza, Jason Potticary, C. Hall, V. Hamilton, S. Hall, G. Santiso‐Quiñones, G. Steinfeld, E. Hovestreydt (2021)
3D electron diffraction for the discovery of new crystal forms of APIsActa Crystallographica Section A Foundations and Advances
T. Gruene, J. Holstein, G. Clever, B. Keppler (2021)
Establishing electron diffraction in chemical crystallographyNature Reviews Chemistry, 5
(1956)
Kinematic theory of intensities in electron diffraction patterns : Part II — Patterns from textures and polycrystalline aggregates
M. Burla, R. Caliandro, B. Carrozzini, G. Cascarano, C. Cuocci, C. Giacovazzo, M. Mallamo, A. Mazzone, G. Polidori (2015)
Crystal structure determination and refinement via SIR2014Journal of Applied Crystallography, 48
E. Mugnaioli, T. Gorelik, U. Kolb (2009)
"Ab initio" structure solution from electron diffraction data obtained by a combination of automated diffraction tomography and precession technique.Ultramicroscopy, 109 6
S. Iijima (2008)
High resolution electron microscopy, 53
J. Wennmacher, C. Zaubitzer, Teng Li, Y. Bahk, Jing Wang, J. Bokhoven, T. Gruene (2019)
3D-structured supports create complete data sets for electron crystallographyNature Communications, 10
M. Gemmi, H. Klein, A. Rageau, P. Strobel, F. Cras (2010)
Structure solution of the new titanate Li4Ti8Ni3O21 using precession electron diffraction.Acta crystallographica. Section B, Structural science, 66 Pt 1
T. Gorelik, C. Czech, Sonja Hammer, M. Schmidt (2016)
Crystal structure of disordered nanocrystalline αII-quinacridone determined by electron diffractionCrystEngComm, 18
R. Martínez-Franco, M. Moliner, Yifeng Yun, Junliang Sun, W. Wan, X. Zou, A. Corma (2013)
Synthesis of an extra-large molecular sieve using proton sponges as organic structure-directing agentsProceedings of the National Academy of Sciences, 110
Christina Birkel, E. Mugnaioli, T. Gorelik, U. Kolb, M. Panthöfer, W. Tremel (2010)
Solution synthesis of a new thermoelectric Zn(1+x)Sb nanophase and its structure determination using automated electron diffraction tomography.Journal of the American Chemical Society, 132 28
M. Clabbers, S. Fisher, M. Coincon, X. Zou, Hongyi Xu (2020)
Visualizing drug binding interactions using microcrystal electron diffractionCommunications Biology, 3
(1936)
La struttura della catena paraffinica studiata mediante i raggi di elettroni
T. Nakane, A. Kotecha, A. Sente, G. McMullan, S. Masiulis, P.M.G.E. Brown, I. Grigoras, L. Malinauskaite, T. Malinauskas, J. Miehling, Lingbo Yu, D. Karia, E. Pechnikova, Erwin Jong, J. Keizer, M. Bischoff, J. McCormack, P. Tiemeijer, S. Hardwick, D. Chirgadze, G. Murshudov, A. Aricescu, S. Scheres (2020)
Single-particle cryo-EM at atomic resolutionNature, 587
D. Marvin (2017)
Fibre diffraction studies of biological macromolecules.Progress in biophysics and molecular biology, 127
M. Gemmi, E. Mugnaioli, T. Gorelik, U. Kolb, L. Palatinus, P. Boullay, S. Hovmöller, J. Abrahams (2019)
3D Electron Diffraction: The Nanocrystallography RevolutionACS Central Science, 5
Dilyana Georgieva, J. Jansen, I. Sikharulidze, Linhua Jiang, H. Zandbergen, J. Abrahams (2011)
Evaluation of Medipix2 detector for recording electron diffraction data in low dose conditionsJournal of Instrumentation, 6
L. McCusker, C. Baerlocher (2012)
Electron crystallography as a complement to X-ray powder diffraction techniques, 228
K. Shankland, Mark Spillman, E. Kabova, David Edgeley, N. Shankland (2013)
The principles underlying the use of powder diffraction data in solving pharmaceutical crystal structures.Acta crystallographica. Section C, Crystal structure communications, 69 Pt 11
I. Rozhdestvenskaya, I. Rozhdestvenskaya, E. Mugnaioli, M. Czank, W. Depmeier, U. Kolb, A. Reinholdt, T. Weirich (2010)
The structure of charoite, (K,Sr,Ba,Mn)15-16(Ca,Na)32[(Si70(O,OH)180)](OH,F)4.0‧nH2O, solved by conventional and automated electron diffractionMineralogical Magazine, 74
(1956)
Structure Analysis by Electron Diffraction
(1967)
3D electron diffraction for structure determination of small-molecule nanocrystals: A possible breakthrough for the pharmaceutical industry
Y. Krysiak, B. Marler, Bastian Barton, S. Plana-Ruiz, H. Gies, R. Neder, U. Kolb (2020)
New zeolite-like RUB-5 and its related hydrous layer silicate RUB-6 structurally characterized by electron microscopyIUCrJ, 7
S. Ito, F. White, E. Okunishi, Y. Aoyama, A. Yamano, Hiroyasu Sato, J. Ferrara, M. Jasnowski, M. Meyer (2021)
Structure determination of small molecule compounds by an electron diffractometer for 3D ED/MicroEDCrystEngComm
Sofia Takki, Hongyi Xu (2017)
Elucidation of the elusive structure and formula of the active pharmaceutical ingredient bismuth subgallate by continuous rotation electron diffraction.Chemical communications, 53 52
M. Clabbers, T. Gruene, J. Parkhurst, J. Abrahams, D. Waterman (2018)
Electron diffraction data processing with DIALSActa Crystallographica. Section D, Structural Biology, 74
U. Kolb, T. Gorelik, E. Mugnaioli, A. Stewart (2010)
Structural Characterization of Organics Using Manual and Automated Electron DiffractionPolymer Reviews, 50
Zhehao Huang, Erik Grape, Jian Li, A. Inge, X. Zou (2021)
3D electron diffraction as an important technique for structure elucidation of metal-organic frameworks and covalent organic frameworksCoordination Chemistry Reviews, 427
Yi Luo, Bin Wang, S. Smeets, Junliang Sun, Weimin Yang, X. Zou (2021)
Exploring Polycrystalline Materials: High-throughput Phase Elucidation Using Serial Rotation Electron Diffraction
M. Lightowler, Shuting Li, X. Ou, X. Zou, M. Lu, Hongyi Xu (2021)
Indomethacin Polymorph δ Revealed To Be Two Plastically Bendable Crystal Forms by 3D Electron Diffraction: Correcting a 47‐Year‐Old MisunderstandingAngewandte Chemie (International Ed. in English), 61
E. Kabova, C. Blundell, K. Shankland (2018)
Pushing the Limits of Molecular Crystal Structure Determination From Powder Diffraction Data in High-Throughput Chemical Environments.Journal of pharmaceutical sciences, 107 8
A. Prabu, V. Chithambaram, M. Antobennet, S. Shanmugan (2020)
A review on various CMOS circuit stylesMaterials Today: Proceedings, 30
I. Andrusenko, V. Hamilton, A. Lanza, C. Hall, E. Mugnaioli, Jason Potticary, A. Buanz, S. Gaisford, A. Piras, Y. Zambito, S. Hall, M. Gemmi (2021)
Structure determination, thermal stability and dissolution rate of δ-indomethacin.International journal of pharmaceutics
Dan Shi, B. Nannenga, M. Cruz, Jin-Ying Liu, S. Sawtelle, G. Calero, F. Reyes, J. Hattne, T. Gonen (2016)
The collection of MicroED data for macromolecular crystallographyNature Protocols, 11
Carina Schlesinger, Sonja Hammer, T. Gorelik, M. Schmidt (2020)
Orientational disorder of monomethyl-quinacridone investigated by Rietveld refinement, structure refinement to the pair distribution function and lattice-energy minimizations.Acta crystallographica Section B, Structural science, crystal engineering and materials, 76 Pt 3
M. Clabbers, E. Genderen, W. Wan, E. Wiegers, T. Gruene, J. Abrahams (2017)
Protein structure determination by electron diffraction using a single three-dimensional nanocrystalActa Crystallographica. Section D, Structural Biology, 73
K. Zinn (1973)
Transmission electron microscopy.International ophthalmology clinics, 13 3
J., Spence, Zuo (2020)
Electron MicrodiffractionCatalysis from A to Z
U. Kolb, T. Gorelik, C. Kübel, M. Otten, D. Hubert (2007)
Towards automated diffraction tomography: part I--data acquisition.Ultramicroscopy, 107 6-7
P. Piccoli, T. Koetzle, A. Schultz (2007)
SINGLE CRYSTAL NEUTRON DIFFRACTION FOR THE INORGANIC CHEMIST – A PRACTICAL GUIDEComments on Inorganic Chemistry, 28
J. Bruhn, G. Scapin, A. Cheng, B. Mercado, D. Waterman, Thejusvi Ganesh, S. Dallakyan, B. Read, Travis Nieusma, Kyle Lucier, Megan Mayer, Nicole Chiang, N. Poweleit, P. McGilvray, Timothy Wilson, Michael Mashore, Camille Hennessy, Sean Thomson, Bo Wang, C. Potter, B. Carragher (2021)
Small Molecule Microcrystal Electron Diffraction for the Pharmaceutical Industry–Lessons Learned From Examining Over Fifty SamplesFrontiers in Molecular Biosciences, 8
Christopher Jones, M. Martynowycz, J. Hattne, Tyler Fulton, B. Stoltz, José Rodríguez, H. Nelson, T. Gonen (2018)
The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure DeterminationACS Central Science, 4
D. Jacques, J. Trewhella (2010)
Small‐angle scattering for structural biology—Expanding the frontier while avoiding the pitfallsProtein Science, 19
G. Sheldrick (2015)
SHELXT – Integrated space-group and crystal-structure determinationActa Crystallographica. Section A, Foundations and Advances, 71
Guillaume Combes, Ana-Marija Vučković, Martina Bakulić, R. Antoine, V. Bonačić‐Koutecký, Katarina Trajković (2021)
Nanotechnology in Tumor Biomarker Detection: The Potential of Liganded Nanoclusters as Nonlinear Optical Contrast Agents for Molecular Diagnostics of CancerCancers, 13
H. Klein, S. Kodjikian, Rémy Philippe, Lei Ding, C. Colin, C. Darie, P. Bordet (2020)
Three different Ge environments in a new Sr5CuGe9O24 phase synthesized at high pressure and high temperature.Acta crystallographica Section B, Structural science, crystal engineering and materials, 76 Pt 5
S. Smeets, X. Zou, W. Wan (2018)
Serial electron crystallography for structure determination and phase analysis of nanocrystalline materialsJournal of Applied Crystallography, 51
M. Gemmi, X. Zou, S. Hovmöller, A. Migliori, M. Vennström, Y. Andersson (2003)
Structure of Ti2P solved by three-dimensional electron diffraction data collected with the precession technique and high-resolution electron microscopy.Acta crystallographica. Section A, Foundations of crystallography, 59 Pt 2
Jin Kim, Sera Park, Dongbo Min, Wankyu Kim (2021)
Comprehensive Survey of Recent Drug Discovery Using Deep LearningInternational Journal of Molecular Sciences, 22
A. Huq (2020)
Powder diffractionNature Reviews Methods Primers, 1
E. Mugnaioli, T. Gorelik (2019)
Structure analysis of materials at the order-disorder borderline using three-dimensional electron diffraction.Acta crystallographica Section B, Structural science, crystal engineering and materials, 75 Pt 4
Jiuxing Jiang, J. Jordá, Jihong Yu, L. Baumes, E. Mugnaioli, M. Díaz-Cabañas, U. Kolb, A. Corma (2011)
Synthesis and Structure Determination of the Hierarchical Meso-Microporous Zeolite ITQ-43Science, 333
S. Nicolopoulos, J. González-Calbet, M. Vallet‐Regí, A. Corma, C. Corell, J. Guil, J. Pérez-Pariente (1995)
DIRECT PHASING IN ELECTRON CRYSTALLOGRAPHY : AB INITIO DETERMINATION OF A NEW MCM-22 ZEOLITE STRUCTUREJournal of the American Chemical Society, 117
W. Wan, Junliang Sun, Jie Su, S. Hovmöller, X. Zou (2013)
Three-dimensional rotation electron diffraction: software RED for automated data collection and data processingJournal of Applied Crystallography, 46
P. Rakowska, M. Ryadnov (2011)
Nano-enabled biomarker discovery and detection.Biomarkers in medicine, 5 3
M. Cichocka, J. Ångström, Bin Wang, X. Zou, S. Smeets (2018)
High-throughput continuous rotation electron diffraction data acquisition via software automationJournal of Applied Crystallography, 51
S. Masiulis, Rooma Desai, T. Uchański, I. Martin, D. Laverty, D. Karia, T. Malinauskas, J. Zivanov, E. Pardon, A. Kotecha, J. Steyaert, K. Miller, A. Aricescu (2019)
GABAA receptor signalling mechanisms revealed by structural pharmacologyNature, 565
D. Dorset, H. Hauptman (1976)
Direct phase determination for quasi-kinematical electron diffraction intensity data from organic microcrystals.Ultramicroscopy, 1 3
E. Grape, V. Rooth, Mathias Nero, T. Willhammar, A. Inge (2021)
Structure of the active pharmaceutical ingredient bismuth subsalicylateNature Communications, 13
Magda Białkowska, W. Chaładaj, I. Deperasińska, Aleksandra Drzewiecka-Antonik, A. Kozioł, A. Makarewicz, B. Kozankiewicz (2017)
Single molecules of terrylene in di-substituted naphthalenes crystallizing in the herringbone patternRSC Advances, 7
T. Welberry, T. Weber (2016)
One hundred years of diffuse scatteringCrystallography Reviews, 22
A. Howie, M. Whelan (1961)
Diffraction contrast of electron microscope images of crystal lattice defects - II. The development of a dynamical theoryProceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences, 263
K. Dierksen, D. Typke, R. Hegerl, A. Koster, W. Baumeister (1992)
Towards automatic electron tomographyUltramicroscopy, 40
郭可信 (2005)
评介“High energy electron diffraction and microscopy”一书
E. Genderen, E. Genderen, M. Clabbers, M. Clabbers, P. Das, A. Stewart, I. Nederlof, K. Barentsen, Q. Portillo, N. Pannu, S. Nicolopoulos, T. Gruene, J. Abrahams, J. Abrahams, J. Abrahams (2016)
Ab initio structure determination of nanocrystals of organic pharmaceutical compounds by electron diffraction at room temperature using a Timepix quantum area direct electron detectorActa Crystallographica. Section A, Foundations and Advances, 72
W. Steurer (2002)
Electron diffraction structure analysis: structural research with low-quality diffraction data
P. Das, I. Andrusenko, E. Mugnaioli, J. Kaduk, S. Nicolopoulos, M. Gemmi, Nicholas Boaz, A. Gindhart, T. Blanton (2021)
Crystal Structure of Linagliptin Hemihydrate Hemiethanolate (C25H28N8O2)2(H2O)(C2H5OH) from 3D Electron Diffraction Data, Rietveld Refinement, and Density Functional Theory OptimizationCrystal Growth & Design, 21
D. Denysenko, M. Grzywa, Markus Tonigold, B. Streppel, I. Krkljuš, M. Hirscher, E. Mugnaioli, U. Kolb, J. Hanss, D. Volkmer (2011)
Elucidating gating effects for hydrogen sorption in MFU-4-type triazolate-based metal-organic frameworks featuring different pore sizes.Chemistry, 17 6
K. Shankland, W. David, D. Sivia (1997)
Routine ab initio structure determination of chlorothiazideby X-ray powder diffraction using optimised data collection and analysisstrategiesJournal of Materials Chemistry, 7
B. Zvyagin (1967)
Electron-Diffraction Analysis of Clay Mineral Structures
Xing Zhang, E. Settembre, Chen Xu, P. Dormitzer, Richard Bellamy, S. Harrison, N. Grigorieff (2008)
Near-atomic resolution using electron cryomicroscopy and single-particle reconstructionProceedings of the National Academy of Sciences, 105
D., H. Wills (2016)
Convergent beam electron diffraction
G. Bellussi, E. Montanari, E. Paola, R. Millini, A. Carati, C. Rizzo, W. Parker, M. Gemmi, E. Mugnaioli, U. Kolb, S. Zanardi (2012)
ECS-3: a crystalline hybrid organic-inorganic aluminosilicate with open porosity.Angewandte Chemie, 51 3
Kenneth Taylor, R. Glaeser (1976)
Electron microscopy of frozen hydrated biological specimens.Journal of ultrastructure research, 55 3
M. Gemmi, Maria-Grazia Placa, A. Galanis, E. Rauch, S. Nicolopoulos (2015)
Fast electron diffraction tomographyActa Crystallographica Section A, 71
I. Andrusenko, V. Hamilton, E. Mugnaioli, A. Lanza, C. Hall, Jason Potticary, S. Hall, M. Gemmi (2019)
The crystal structure of orthocetamol solved by 3D electron diffraction.Angewandte Chemie
S. Kodjikian, H. Klein (2019)
Low-dose electron diffraction tomography (LD-EDT).Ultramicroscopy, 200
U. Kolb, E. Mugnaioli, T. Gorelik (2011)
Automated electron diffraction tomography – a new tool for nano crystal structure analysisCrystal Research and Technology, 46
D. Dorset (1995)
Structural Electron Crystallography
K. Gjønnes, Y. Cheng, B. Berg, V. Hansen (1998)
Corrections for multiple scattering in integrated electron diffraction intensities. Application to determination of structure factors in the [001] projection of AlmFeActa Crystallographica Section A, 54
P. Das, E. Mugnaioli, S. Nicolopoulos, C. Tossi, C. Tossi, M. Gemmi, Athanasios Galanis, G. Borodi, M. Pop (2018)
Crystal Structures of Two Important Pharmaceuticals Solved by 3D Precession Electron Diffraction TomographyOrganic Process Research & Development
T. Gorelik, J. Streek, Andreas Kilbinger, G. Brunklaus, U. Kolb (2012)
Ab-initio crystal structure analysis and refinement approaches of oligo p-benzamides based on electron diffraction data.Acta crystallographica. Section B, Structural science, 68 Pt 2
B. Fultz, J. Howe (2001)
Transmission electron microscopy and diffractometry of materials
T. Weil, T. Vosch, J. Hofkens, K. Peneva, K. Müllen (2010)
The rylene colorant family--tailored nanoemitters for photonics research and applications.Angewandte Chemie, 49 48
D. Dorset (2007)
Electron crystallography of organic materials.Ultramicroscopy, 107 6-7
P. Brázda, L. Palatinus, M. Babor (2019)
Electron diffraction determines molecular absolute configuration in a pharmaceutical nanocrystalScience, 364
T. Uchański, S. Masiulis, B. Fischer, V. Kalichuk, Uriel López-Sánchez, E. Zarkadas, M. Weckener, A. Sente, Philip Ward, Alexandre Wohlkönig, Thomas Zögg, H. Remaut, James Naismith, H. Nury, W. Vranken, A. Aricescu, E. Pardon, J. Steyaert (2019)
Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EMNature Methods, 18
A. F. (1936)
Electron DiffractionNature, 137
R. Glaeser, M. Facciotti, P. Walian, S. Rouhani, J. Holton, A. MacDowell, R. Celestre, D. Cambie, H. Padmore (2000)
Characterization of conditions required for X-Ray diffraction experiments with protein microcrystals.Biophysical journal, 78 6
J. Jansen, D. Tang, H. Zandbergen, H. Schenk (1998)
MSLS, a Least-Squares Procedure for Accurate Crystal Structure Refinement from Dynamical Electron Diffraction PatternsActa Crystallographica Section A, 54
M. Gemmi, P. Oleynikov (2012)
Scanning reciprocal space for solving unknown structures: energy filtered diffraction tomography and rotation diffraction tomography methods, 228
T. Willhammar, Junliang Sun, W. Wan, P. Oleynikov, Daliang Zhang, X. Zou, M. Moliner, Jorge González, C. Martínez, F. Rey, A. Corma (2012)
Structure and catalytic properties of the most complex intergrown zeolite ITQ-39 determined by electron crystallography.Nature chemistry, 4 3
T. Gruene, J. Wennmacher, Christan Zaubitzer, J. Holstein, J. Heidler, Ariane Fecteau-Lefebvre, S. Carlo, Elisabeth Müller, K. Goldie, I. Regeni, Teng Li, G. Santiso‐Quiñones, G. Steinfeld, S. Handschin, E. Genderen, J. Bokhoven, G. Clever, R. Pantelic (2018)
Rapid Structure Determination of Microcrystalline Molecular Compounds Using Electron DiffractionAngewandte Chemie (International Ed. in English), 57
I. Andrusenko, E. Mugnaioli, T. Gorelik, Dominik Koll, M. Panthöfer, W. Tremel, U. Kolb (2011)
Structure analysis of titanate nanorods by automated electron diffraction tomography.Acta crystallographica. Section B, Structural science, 67 Pt 3
R. Bücker, P. Hogan-Lamarre, P. Mehrabi, E. Schulz, Lindsey Bultema, Y. Gevorkov, W. Brehm, O. Yefanov, D. Oberthür, G. Kassier, R. Miller (2019)
Serial protein crystallography in an electron microscopeNature Communications, 11
Xuekui Yu, Xuekui Yu, Lei Jin, Lei Jin, Z. Zhou, Z. Zhou (2008)
3.88 Å structure of cytoplasmic polyhedrosis virus by cryo-electron microscopyNature, 453
T. Weirich (2003)
Electron diffraction structure analysis: structural research with low-quality diffraction dataZeitschrift für Kristallographie - Crystalline Materials, 218
C. Hall, I. Andrusenko, Jason Potticary, Siyu Gao, Xingyu Liu, W. Schmidt, N. Marom, E. Mugnaioli, M. Gemmi, S. Hall (2021)
3D Electron Diffraction Structure Determination of Terrylene, a Promising Candidate for Intermolecular Singlet FissionChemphyschem, 22
K. Urban (2008)
Studying Atomic Structures by Aberration-Corrected Transmission Electron MicroscopyScience, 321
T. Gruene, E. Mugnaioli (2021)
3D Electron Diffraction for Chemical Analysis: Instrumentation Developments and Innovative ApplicationsChemical Reviews, 121
G. Tinti, E. Fröjdh, E. Genderen, T. Gruene, B. Schmitt, D. Winter, B. Weckhuysen, J. Abrahams (2018)
Electron crystallography with the EIGER detectorIUCrJ, 5
Masaki Yamamoto, K. Hirata, K. Yamashita, K. Hasegawa, G. Ueno, H. Ago, T. Kumasaka (2017)
Protein microcrystallography using synchrotron radiationIUCrJ, 4
P. Wagner, O. Terasaki, S. Ritsch, J. Nery, S. Zones, Mark Davis, K. Hiraga (1999)
Electron Diffraction Structure Solution of a Nanocrystalline Zeolite at Atomic ResolutionJournal of Physical Chemistry B, 103
(1968)
Physical principles and certain results of the modern electron diffraction structure analysis
M. Wacker, A. Proykova, Gustavo Santos (2016)
Dealing with nanosafety around the globe-Regulation vs. innovation.International journal of pharmaceutics, 509 1-2
Daliang Zhang, P. Oleynikov, S. Hovmöller, X. Zou (2010)
Collecting 3D electron diffraction data by the rotation method, 225
M. Clabbers, Hongyi Xu (2020)
Microcrystal electron diffraction in macromolecular and pharmaceutical structure determination.Drug discovery today. Technologies, 37
(1964)
Fourier synthesis of potential in electron diffraction structure analysis and its applications to the study of hydrogen atoms
N. Ohnishi, K. Hiraga (1996)
Slow-Scan CCD Camera Analysis of Electron Diffraction and High-Resolution Micrographs of Zeolite TPA/ZSM-5Journal of Electron Microscopy, 45
T. Weirich, J. Portillo, G. Cox, H. Hibst, S. Nicolopoulos (2006)
Ab initio determination of the framework structure of the heavy-metal oxide Cs(x)Nb2.54W2.46O14 from 100 kV precession electron diffraction data.Ultramicroscopy, 106 3
D. Dorset (1989)
Electron crystallography of organic materials.Journal of electron microscopy technique, 11 4
S. Plana-Ruiz, S. Plana-Ruiz, Y. Krysiak, J. Portillo, E. Alig, S. Estradé, F. Peiró, U. Kolb, U. Kolb (2020)
Fast-ADT: A fast and automated electron diffraction tomography setup for structure determination and refinement.Ultramicroscopy, 211
P. Boullay, L. Palatinus, N. Barrier (2013)
Precession electron diffraction tomography for solving complex modulated structures: the case of Bi5Nb3O15.Inorganic chemistry, 52 10
C. Coulson (1953)
Molecular ArchitectureNature, 172
B. Nannenga (2019)
MicroED methodology and developmentStructural Dynamics, 7
D. Rogers (1954)
Determination of Crystal StructuresNature, 174
Yi Jiang, Zhen Chen, Yimo Han, P. Deb, Hui Gao, Saien Xie, P. Purohit, M. Tate, Jiwoong Park, S. Gruner, V. Elser, D. Muller (2018)
Electron ptychography of 2D materials to deep sub-ångström resolutionNature, 559
A. Zhukhlistov, A. Avilov, D. Ferraris, B. Zvyagin, V. Plotnikov (1997)
Statistical distribution of hydrogen over three positions in the brucite Mg(OH) 2 structure from electron diffractometry data, 42
E. Broadhurst, Hongyi Xu, S. Parsons, F. Nudelman (2021)
Revealing the early stages of carbamazepine crystallization by cryoTEM and 3D electron diffractionIUCrJ, 8
Yue‐Biao Zhang, Jie Su, H. Furukawa, Yifeng Yun, F. Gándara, A. Duong, X. Zou, O. Yaghi (2013)
Single-crystal structure of a covalent organic framework.Journal of the American Chemical Society, 135 44
W. Chiu (1986)
Electron microscopy of frozen, hydrated biological specimens.Annual review of biophysics and biophysical chemistry, 15
I. Voigt-martin, D. Yan, A. Yakimansky, D. Schollmeyer, C. Gilmore, G. Bricogne (1995)
Structure determination by electron crystallography using both maximum-entropy and simulation approachesActa Crystallographica Section A, 51
D. Danino (2012)
Cryo-TEM of soft molecular assembliesCurrent Opinion in Colloid and Interface Science, 17
L. Palatinus, G. Chapuis (2007)
SUPERFLIP– a computer program for the solution of crystal structures by charge flipping in arbitrary dimensionsJournal of Applied Crystallography, 40
(1995)
Diffraction physics (3rd ed.)
R. Heidenreich (1964)
Fundamentals of Transmission Electron Microscopy
Youdong Mao, Luis Castillo-Menendez, Liping Wang, Christopher Gu, Alon Herschhorn, A. Désormeaux, A. Finzi, S. Xiang, J. Sodroski (2013)
Molecular architecture of the uncleaved HIV-1 envelope glycoprotein trimerRetrovirology, 10
R. Vincent, P. Midgley (1994)
Double conical beam-rocking system for measurement of integrated electron diffraction intensitiesUltramicroscopy, 53
T. Weirich, R. Ramlau, A. Simon, S. Hovmöller, X. Zou (1996)
A crystal structure determined with 0.02 Å accuracy by electron microscopyNature, 382
R. Černý (2017)
Crystal Structures from Powder Diffraction: Principles, Difficulties and Progress, 7
D. Dorset, W. Roth, C. Gilmore (2005)
Electron crystallography of zeolites--the MWW family as a test of direct 3D structure determination.Acta crystallographica. Section A, Foundations of crystallography, 61 Pt 5
W. David, K. Shankland (2008)
Structure determination from powder diffraction data.Acta crystallographica. Section A, Foundations of crystallography, 64 Pt 1
I. Andrusenko, Jason Potticary, S. Hall, M. Gemmi (2020)
A new olanzapine cocrystal obtained from volatile deep eutectic solvents and determined by 3D electron diffraction.Acta crystallographica Section B, Structural science, crystal engineering and materials, 76 Pt 6
S. Sedlmaier, E. Mugnaioli, O. Oeckler, U. Kolb, W. Schnick (2011)
SrP3N5O: a highly condensed layer phosphate structure solved from a nanocrystal by automated electron diffraction tomography.Chemistry, 17 40
P. Thiessen, T. Schoon (1937)
Elektronenbeugung an natürlichen Flächen organischer EinkristalleZeitschrift für Physikalische Chemie, 36B
T. Schoon (1938)
Polymorphe Formen kristalliner Kohlenstoffverbindungen mit langen gestreckten KettenZeitschrift für Physikalische Chemie, 39B
Nanomedicine is among the most fascinating areas of research. Most of the newly discovered pharmaceutical polymorphs, as well as many new synthesized or isolated natural products, appear only in form of nanocrystals. The development of techniques that allow investigating the atomic structure of nanocrystalline materials is therefore one of the most important frontiers of crystallography. Some unique features of electrons, like their non‐neutral charge and their strong interaction with matter, make this radiation suitable for imaging and detecting individual atoms, molecules, or nanoscale objects down to sub‐angstrom resolution. In the recent years the development of three‐dimensional (3D) electron diffraction (3D ED) has shown that electron diffraction can be successfully used to solve the crystal structure of nanocrystals and most of its limiting factors like dynamical scattering or limited completeness can be easily overcome. This article is a review of the state of the art of this method with a specific focus on how it can be applied to beam sensitive samples like small‐molecule organic nanocrystals.
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology – Wiley
Published: Sep 1, 2022
Keywords: 3D electron diffraction; electron crystallography; pharmaceutics; small‐molecule organics; structure solution
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.