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2012 C arl‐ G ustav G roth X eno P rize, and the winner is

2012 C arl‐ G ustav G roth X eno P rize, and the winner is We are very pleased to announce the winner selected by the prize committee to receive the 2012 Carl‐Gustav Groth Xeno Prize: Burlak C, Wang ZY, Chihara RK, Lutz AJ, Wang Y, Estrada JL, Tector AJ. Identification of human preformed antibody targets in GTKO pigs. Xenotransplantation 2012; 19: 92–101. This elegant study analyzed and identified several new targets for natural human IgG and IgM present on porcine galactosyltransferase KO pig cells. These results help us to better understand the remaining antigenicity of genetically modified pig tissues that still needs to be improved. This study was chosen among six papers pre‐selected by the editorial board and presented to the prize committee. The other nominated studies were (by chronological order) as follows: Paris LL, Chihara RK, Sidner RA, Tector AJ, Burlak C. Differences in human and porcine platelet oligosaccharides may influence phagocytosis by liver sinusoidal cells in vitro. Xenotransplantation 2012; 19: 31–39. Kemter E, Lieke T, Kessler B, Kurome M, Wuensch A, Summerfield A, Ayares D, Nagashima H, Baars W, Schwinzer R, Wolf E. Human TNF‐related apoptosis‐inducing ligand‐expressing dendritic cells from transgenic pigs attenuate human xenogeneic T cell responses. Xenotransplantation 2012; 19: 40–51. Wilhite T, Ezzelarab C, Hara H, Long C, Ayares D, Cooper DKC, Ezzelarab M. The effect of Gal expression on pig cells on the human T cell xenoresponse. Xenotransplantation 2012; 19: 56–63. Ezzelarab MB, Ekser B, Echeverri G, Hara H, Ezzelarab C, Long C, Bajona P, Garcia B, Murase N, Ayares D, Cooper DKC. Costimulation blockade in pig artery patch xenotransplantation – a simple model to monitor the adaptive immune response in nonhuman primates. Xenotransplantation 2012; 19: 221–232. Iwase H, Ekser B, Zhou H, Dons EM, Cooper DKC, Ezzelarab MB. Platelet aggregation in humans and nonhuman primates: relevance to xenotransplantation. Xenotransplantation 2012; 19: 233–243. The prize of US $7000 will be presented to the winner at the IXA congress in Osaka, 10–13 November 2013. On behalf of IXA and the publisher of Xenotransplantation (Wiley), we congratulate Dr Burlak and his team. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Xenotransplantation Wiley

2012 C arl‐ G ustav G roth X eno P rize, and the winner is

Hering, Bernhard J.; Buhler, Leo
Xenotransplantation , Volume 20 (2) – Mar 1, 2013
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References (4)

Publisher
Wiley
Copyright
© 2013 John Wiley & Sons A/S
ISSN
0908-665X
eISSN
1399-3089
DOI
10.1111/xen.12029
Publisher site
See Article on Publisher Site

Abstract

We are very pleased to announce the winner selected by the prize committee to receive the 2012 Carl‐Gustav Groth Xeno Prize: Burlak C, Wang ZY, Chihara RK, Lutz AJ, Wang Y, Estrada JL, Tector AJ. Identification of human preformed antibody targets in GTKO pigs. Xenotransplantation 2012; 19: 92–101. This elegant study analyzed and identified several new targets for natural human IgG and IgM present on porcine galactosyltransferase KO pig cells. These results help us to better understand the remaining antigenicity of genetically modified pig tissues that still needs to be improved. This study was chosen among six papers pre‐selected by the editorial board and presented to the prize committee. The other nominated studies were (by chronological order) as follows: Paris LL, Chihara RK, Sidner RA, Tector AJ, Burlak C. Differences in human and porcine platelet oligosaccharides may influence phagocytosis by liver sinusoidal cells in vitro. Xenotransplantation 2012; 19: 31–39. Kemter E, Lieke T, Kessler B, Kurome M, Wuensch A, Summerfield A, Ayares D, Nagashima H, Baars W, Schwinzer R, Wolf E. Human TNF‐related apoptosis‐inducing ligand‐expressing dendritic cells from transgenic pigs attenuate human xenogeneic T cell responses. Xenotransplantation 2012; 19: 40–51. Wilhite T, Ezzelarab C, Hara H, Long C, Ayares D, Cooper DKC, Ezzelarab M. The effect of Gal expression on pig cells on the human T cell xenoresponse. Xenotransplantation 2012; 19: 56–63. Ezzelarab MB, Ekser B, Echeverri G, Hara H, Ezzelarab C, Long C, Bajona P, Garcia B, Murase N, Ayares D, Cooper DKC. Costimulation blockade in pig artery patch xenotransplantation – a simple model to monitor the adaptive immune response in nonhuman primates. Xenotransplantation 2012; 19: 221–232. Iwase H, Ekser B, Zhou H, Dons EM, Cooper DKC, Ezzelarab MB. Platelet aggregation in humans and nonhuman primates: relevance to xenotransplantation. Xenotransplantation 2012; 19: 233–243. The prize of US $7000 will be presented to the winner at the IXA congress in Osaka, 10–13 November 2013. On behalf of IXA and the publisher of Xenotransplantation (Wiley), we congratulate Dr Burlak and his team.

Journal

Xenotransplantation – Wiley

Published: Mar 1, 2013

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