Access the full text.
Sign up today, get DeepDyve free for 14 days.
GW Moeckel, M Kashgarian, L Racusen, JC Jennette, JL Olson, FG Silva, VD D’Agati (2015)
Ischemic and toxic acute tubular injury and other ischemic injuries
A. Polichnowski, K. Griffin, Hector Licea-Vargas, R. Lan, M. Picken, Jainrui Long, G. Williamson, C. Rosenberger, S. Mathia, M. Venkatachalam, A. Bidani (2020)
Pathophysiology of unilateral ischemia-reperfusion injury: importance of renal counterbalance and implications for the AKI-CKD transition.American journal of physiology. Renal physiology
C. Parikh, Sherry Mansour (2017)
Perspective on Clinical Application of Biomarkers in AKI.Journal of the American Society of Nephrology : JASN, 28 6
C Ronco, R Bellomo, JA Kellum (2019)
Acute kidney injury, 394
H. Gundersen, E. Jensen, K. Kiêu, J. Nielsen (1999)
The efficiency of systematic sampling in stereology — reconsideredJournal of Microscopy, 193
E. Hoste, J. Kellum, N. Selby, A. Zarbock, P. Palevsky, S. Bagshaw, S. Goldstein, J. Cerdá, L. Chawla (2018)
Global epidemiology and outcomes of acute kidney injuryNature Reviews Nephrology, 14
G. Nomura, E. Kinoshita, Y. Yamagata, N. Koga (1984)
Usefulness of Renal Ultrasonography for Assessment of Severity and Course of Acute Tubular NecrosisJournal of Clinical Ultrasound, 12
A. Polichnowski, R. Lan, H. Geng, K. Griffin, M. Venkatachalam, A. Bidani (2014)
Severe renal mass reduction impairs recovery and promotes fibrosis after AKI.Journal of the American Society of Nephrology : JASN, 25 7
Qingqing Wei, Z. Dong (2012)
Mouse model of ischemic acute kidney injury: technical notes and tricks.American journal of physiology. Renal physiology, 303 11
Sarah Ray, J. Mason, P. O’Connor (2019)
Ischemic Renal Injury: Can Renal Anatomy and Associated Vascular Congestion Explain Why the Medulla and Not the Cortex Is Where the Trouble Starts?Seminars in nephrology, 39 6
E. Boesen, G. Crislip, Jennifer Sullivan (2012)
Use of ultrasound to assess renal reperfusion and P-selectin expression following unilateral renal ischemia.American journal of physiology. Renal physiology, 303 9
H. Gundersen, E. Jensen (1987)
The efficiency of systematic sampling in stereology and its prediction *Journal of Microscopy, 147
Azarkish F (2013)
1139Int J Prev Med, 4
S. Vercauteren, D. Ysebaert, K. Greef, E. Eyskens, M. Broe (1999)
Chronic reduction in renal mass in the rat attenuates ischemia/reperfusion injury and does not impair tubular regeneration.Journal of the American Society of Nephrology : JASN, 10 12
R. Lan, H. Geng, A. Polichnowski, P. Singha, P. Saikumar, D. McEwen, K. Griffin, R. Koesters, J. Weinberg, A. Bidani, W. Kriz, M. Venkatachalam (2012)
PTEN loss defines a TGF-β-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis.American journal of physiology. Renal physiology, 302 9
L. Pelander, J. Häggström, A. Larsson, H. Syme, J. Elliott, R. Heiene, I. Ljungvall (2019)
Comparison of the diagnostic value of symmetric dimethylarginine, cystatin C, and creatinine for detection of decreased glomerular filtration rate in dogsJournal of Veterinary Internal Medicine, 33
Li Yang, Tatiana Besschetnova, C. Brooks, J. Shah, J. Bonventre (2010)
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injuryNature Medicine, 16
S. Teo, Z. Endre (2017)
Biomarkers in acute kidney injury (AKI).Best practice & research. Clinical anaesthesiology, 31 3
R. Zager, Ali Johnson, Kirsten Becker (2011)
Acute unilateral ischemic renal injury induces progressive renal inflammation, lipid accumulation, histone modification, and "end-stage" kidney disease.American journal of physiology. Renal physiology, 301 6
F. Husain‐Syed, F. Ferrari, Aashish Sharma, Tommaso Danesi, Pércia Bezerra, Salvador López-Giacoman, S. Samoni, M. Cal, V. Corradi, G. Virzì, S. Rosa, M. Bermejo, C. Estremadoyro, G. Villa, J. Zaragoza, C. Caprara, A. Brocca, H. Birk, H. Walmrath, W. Seeger, F. Nalesso, M. Zanella, A. Brendolan, D. Giavarina, L. Salvador, R. Bellomo, M. Rosner, J. Kellum, C. Ronco (2018)
Persistent decrease of renal functional reserve in patients after cardiac surgery-associated acute kidney injury despite clinical recoveryNephrology Dialysis Transplantation, 34
H. Schiffl, S. Lang, R. Fischer (2012)
Long-term outcomes of survivors of ICU acute kidney injury requiring renal replacement therapy: a 10-year prospective cohort studyClinical Kidney Journal, 5
M. Carattino, F. Cueva, A. Zuccollo, Jose Monti, M. Navarro, O. Catanzaro (1999)
Renal ischemia-induced increase in vascular permeability is limited by hypothermia.Immunopharmacology, 43 2-3
F Azarkish, M Nematbakhsh, M Fazilati, A Talebi, AA Pilehvarian, Z Pezeshki, M Moeini, A Mansouri, T Safari (2013)
N-acetylcysteine prevents kidney and lung disturbances in renal ischemia/reperfusion injury in rat, 4
Fei Fang, George Liu, Xiaohua Zhou, Stuart Yang, H. Reich, Vanessa Williams, A. Hu, J. Pan, A. Konvalinka, G. Oudit, J. Scholey, R. John (2013)
Loss of ACE2 Exacerbates Murine Renal Ischemia-Reperfusion InjuryPLoS ONE, 8
Noninvasive determination of the severity of parenchymal injury in acute kidney injury remains challenging. Edema is an early pathological process following injury, which may correlate with changes in kidney volume. The goal of the present study was to test the hypothesis that “increases in kidney volume measured in vivo using ultrasound correlate with the degree of renal parenchymal injury.” Ischemia-reperfusion (IR) of varying length was used to produce graded tissue injury. We first determined 1) whether regional kidney volume in rats varied with the severity (0, 15, 30, and 45 min) of warm bilateral IR and 2) whether this correlated with tubular injury score. We then determined whether these changes could be measured in vivo using three-dimensional ultrasound. Finally, we evaluated cumulative changes in kidney volume up to 14 days post-IR in rats to determine whether changes in renal volume were predictive of latent tubular injury following recovery of filtration. Experiments concluded that noninvasive ultrasound measurements of change in kidney volume over 2 wk are predictive of tubular injury following IR even in animals in which plasma creatinine was not elevated. We conclude that ultrasound measurements of volume are a sensitive, noninvasive marker of tissue injury in rats and that the use of three-dimensional ultrasound measurements may provide useful information regarding the timing, severity, and recovery from renal tissue injury in experimental studies.
American Journal of Physiology-Renal Physiology – The American Physiological Society
Published: Sep 1, 2020
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.