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The P300 ‘face’ speller is resistant to cognitive decline in ALS

The P300 ‘face’ speller is resistant to cognitive decline in ALS AbstractThree different P300 paradigms, the classic matrix-based speller, one employing faces as stimuli, and one with serial stimulus presentation, were used to assess the effects of cognition and visual function on brain–computer interface (BCI) use in 22 patients with amyotrophic lateral sclerosis (ALS) and 13 control participants. The patients in the study, on average, demonstrated lower accuracy than the matched control participants. Patients had a slightly greater incidence of oculomotor limitations, but this did not translate to a measurable difference in task-specific gaze control or performance on any of the tasks. Lower cognitive screen scores were the only clinical characteristic to consistently reduce evoked responses and P300 accuracies across individuals. The late portion of the evoked potential, 500–800 ms after the stimulus, was most strongly associated with cognitive score. The early evoked potential around 170 ms, generated by the face speller, was not as strongly associated with cognition. The results indicate that patients with neurodegenerative disease may fare better using an oddball-based BCI task employing face stimuli due in part to the early evoked response that is less hindered by cognitive impairment. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Brain-Computer Interfaces Taylor & Francis

The P300 ‘face’ speller is resistant to cognitive decline in ALS

Brain-Computer Interfaces , Volume 4 (4): 11 – Oct 2, 2017

The P300 ‘face’ speller is resistant to cognitive decline in ALS

Abstract

AbstractThree different P300 paradigms, the classic matrix-based speller, one employing faces as stimuli, and one with serial stimulus presentation, were used to assess the effects of cognition and visual function on brain–computer interface (BCI) use in 22 patients with amyotrophic lateral sclerosis (ALS) and 13 control participants. The patients in the study, on average, demonstrated lower accuracy than the matched control participants. Patients had a slightly greater incidence of...
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Publisher
Taylor & Francis
Copyright
© 2017 Informa UK Limited, trading as Taylor & Francis Group
ISSN
2326-2621
eISSN
2326-263x
DOI
10.1080/2326263X.2017.1338013
Publisher site
See Article on Publisher Site

Abstract

AbstractThree different P300 paradigms, the classic matrix-based speller, one employing faces as stimuli, and one with serial stimulus presentation, were used to assess the effects of cognition and visual function on brain–computer interface (BCI) use in 22 patients with amyotrophic lateral sclerosis (ALS) and 13 control participants. The patients in the study, on average, demonstrated lower accuracy than the matched control participants. Patients had a slightly greater incidence of oculomotor limitations, but this did not translate to a measurable difference in task-specific gaze control or performance on any of the tasks. Lower cognitive screen scores were the only clinical characteristic to consistently reduce evoked responses and P300 accuracies across individuals. The late portion of the evoked potential, 500–800 ms after the stimulus, was most strongly associated with cognitive score. The early evoked potential around 170 ms, generated by the face speller, was not as strongly associated with cognition. The results indicate that patients with neurodegenerative disease may fare better using an oddball-based BCI task employing face stimuli due in part to the early evoked response that is less hindered by cognitive impairment.

Journal

Brain-Computer InterfacesTaylor & Francis

Published: Oct 2, 2017

Keywords: P300; N170; amyotrophic lateral sclerosis; electroencephalography

References