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Sentinel node biopsy has replaced routine axillary node dissection for women with clinically node-negative breast cancer. The development of nomograms, predictive models that enable individualized risk estimation, has enabled identification of women that are at low or high risk of residual non-sentinel node disease after a positive sentinel node biopsy, and have been widely validated. Furthermore, such models have been shown to predict risk of regional recurrence, risk of non-sentinel node involvement after neoadjuvant chemotherapy, and risk of four or more positive axillary nodes. Together with the panoply of other data, these mathematical models contribute to optimum and individualized decision making for a woman with breast cancer.
Current Breast Cancer Reports – Springer Journals
Published: Jan 12, 2014
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